1 10-Phenanthroline-5 6-dione 97
- CAS No.
- 27318-90-7
- Chemical Name:
- 1 10-Phenanthroline-5 6-dione 97
- Synonyms
- 1,10-Phenanthroline-5,6-dione;1,10-Phenanthroline-5,6-quinone;11,10-Phenanthroline-5,6-dione, 98%;phen-5,6-dione;Stahl phd oxidant;Phenanthroline-5,6-;dipyridobenzoquinone;Stahl phd oxidant phd;1,10-Phenthroline-5,6-dione;1,10-Phenanthrolin-5,6-dione
- CBNumber:
- CB2499459
- Molecular Formula:
- C12H6N2O2
- Molecular Weight:
- 210.19
- MDL Number:
- MFCD00014473
- MOL File:
- 27318-90-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 260 °C (dec.)(lit.) |
|---|---|
| Boiling point | 456.1±20.0 °C(Predicted) |
| Density | 1.444±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 0.26±0.20(Predicted) |
| form | powder to crystal |
| color | Light yellow to Amber to Dark green |
| Water Solubility | Insoluble in water. |
| λmax | 251nm(MeOH)(lit.) |
| InChI | InChI=1S/C12H6N2O2/c15-11-7-3-1-5-13-9(7)10-8(12(11)16)4-2-6-14-10/h1-6H |
| InChIKey | KCALAFIVPCAXJI-UHFFFAOYSA-N |
| SMILES | N1C2=C(C(=O)C(=O)C3=C2N=CC=C3)C=CC=1 |
| FDA UNII | 8JD7KXA2W0 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
1 10-Phenanthroline-5 6-dione 97 price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 496383 | 1,10-Phenanthroline-5,6-dione 97% | 27318-90-7 | 1g | $227 | 2026-04-30 | Buy |
| TCI Chemical | P1973 | 1,10-Phenanthroline-5,6-dione >98.0%(HPLC)(T) | 27318-90-7 | 1g | $108 | 2026-04-30 | Buy |
| TCI Chemical | P1973 | 1,10-Phenanthroline-5,6-dione >98.0%(HPLC)(T) | 27318-90-7 | 5g | $315 | 2026-04-30 | Buy |
| Usbiological | 288437 | 1,10-Phenanthroline-5,6-dione Asreported | 27318-90-7 | 250mg | $315 | 2026-06-03 | Buy |
| Usbiological | 288437 | 1,10-Phenanthroline-5,6-dione Asreported | 27318-90-7 | 500mg | $435 | 2026-06-03 | Buy |
1 10-Phenanthroline-5 6-dione 97 Chemical Properties, Uses, Production
Chemical Properties
Yellow solid
Uses
1,10-Phenanthroline-5,6-dione is a Bifunctional quinone oxidant which, when used in conjunction with Zn2+ catalysts, is used to affect the aerobic oxidation of secondary amines to a variety of value added motifs, including indoles.
General Description
1,10-Phenanthroline-5,6-dione (phendio) forms Cu(II) and Ag(I) phendio complexes, which show potent anti-fungal and anti-cancer activity. The modification of glassy carbon (GC) electrodes with phendio complexes of transition metals leads to the catalytic oxidation of NADH at low overpotential.
Synthesis
66-71-7
27318-90-7
1. Add 35 mL of concentrated H2SO4 to a 250 mL three-necked flask at 0 °C. 2. 2. 1,10-phenanthroline (2.5 g, 28 mmol) was added slowly to the three-necked flask. 3. KBr (5 g, 42 mmol) and HNO3 (17.5 mL) were added sequentially at 5 °C. 4. Stir the reaction mixture at room temperature for 20 minutes. 5. Warm the reaction system to 130 °C and hold for 2 hours. 6. Slowly pour the hot yellow reaction solution into 150 g of ice water. 7. Neutralize to pH=7 with Na2CO3. 8. Extract the reaction mixture with CHCl3. 9. Combine the organic phases and dry with anhydrous Na2SO4. 10. Concentrate the organic phase under pressure. 11. purify the crude product by recrystallization from anhydrous ethanol to give 2.4 g (96% yield) of 1,10-phenanthroline-5,6-dione.
References
[1] Dalton Transactions, 2016, vol. 45, # 41, p. 16366 - 16378
[2] Chemistry - A European Journal, 2012, vol. 18, # 50, p. 16061 - 16072
[3] Russian Journal of Organic Chemistry, 2005, vol. 41, # 11, p. 1690 - 1693
[4] Journal of the American Chemical Society,
[5] Journal of the American Chemical Society, 2009, vol. 131, p. 4 - 5
1 10-Phenanthroline-5 6-dione 97 Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9ding chemical ( Shanghai) Limited | 021-021-52271985 17721149837 | sales@9dingchem.com | China | 19780 | 60 |
| Linyi Azelasi Biological Co., Ltd. | 17753923223; | 2805221329@qq.com | China | 1472 | 58 |
| Wuhan Roche Technology Development Co., Ltd., | 18986168071; 18986168071 | 18986168071@163.com | China | 97 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
View Latest Price from 1 10-Phenanthroline-5 6-dione 97 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | 1,10-phenanthroline-5,6-dione
27318-90-7
|
1g | 98%min | 10kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-17 | 1,10-Phenanthroline-5,6-dione
27318-90-7
|
$55.00-743.00 | 1g | 0.98 | 10kg | Shanghai UCHEM Inc. | |
 |
2026-05-28 | 1 10-PHENANTHROLINE-5 6-DIONE 97
27318-90-7
|
$100.60 | 1KG | 98% | 5000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 1,10-phenanthroline-5,6-dione
27318-90-7
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 1,10-Phenanthroline-5,6-dione
27318-90-7
- $55.00-743.00
- 0.98
- Shanghai UCHEM Inc.
-
- 1 10-PHENANTHROLINE-5 6-DIONE 97
27318-90-7
- $100.60
- 98%
- Hebei Chuanghai Biotechnology Co,.LTD
27318-90-7 (1 10-Phenanthroline-5 6-dione 97) Related Search:
1of4
