HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
- CAS No.
- 29400-42-8
- Chemical Name:
- HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
- Synonyms
- fumigacin;Helvolic acid, Mycotoxin;Helvolic acid (Fumigacin);HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS;6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)--alph;17(20),24-trien-21-oicacid,6,16-bis(acetyloxy)-3,7-dioxo-29-nordammara-(4;(8α,9β,13α,14β,17Z)-6β,16β-Diacetoxy-3,7-dioxo-29-nor-5α-dammara-1,17(20),24-trien-21-oic acid;(8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid;(4α,8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid;29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4α,6β,8α,9β,13α,14β,16β,17Z)-
- CBNumber:
- CB2503570
- Molecular Formula:
- C33H44O8
- Molecular Weight:
- 568.7
- MDL Number:
- MFCD32689348
- MOL File:
- 29400-42-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 215° |
|---|---|
| alpha | D25 -121° (chloroform) |
| Boiling point | 552.56°C (rough estimate) |
| Density | 1.1062 (rough estimate) |
| refractive index | 1.4900 (estimate) |
| storage temp. | 2-8°C |
| solubility |
DMF:30.0(Max Conc. mg/mL);52.75(Max Conc. mM) DMSO:20.0(Max Conc. mg/mL);35.17(Max Conc. mM) Ethanol:20.0(Max Conc. mg/mL);35.17(Max Conc. mM) |
| form | A crystalline solid |
| pka | 4.05±0.41(Predicted) |
| color | White to off-white |
| FDA UNII | MZX54GS8AH |
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21580 | Helvolic Acid ≥98% | 29400-42-8 | 1mg | $80 | 2026-04-30 | Buy |
| Cayman Chemical | 21580 | Helvolic Acid ≥98% | 29400-42-8 | 5mg | $255 | 2026-04-30 | Buy |
| Biosynth | BH162732 | Helvolic acid | 29400-42-8 | 5mg | $708.4 | 2026-06-04 | Buy |
| Biosynth | BH162732 | Helvolic acid | 29400-42-8 | 10mg | $1181.3 | 2026-06-04 | Buy |
| Biosynth | BH162732 | Helvolic acid | 29400-42-8 | 50mg | $3935.5 | 2026-06-04 | Buy |
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Chemical Properties,Uses,Production
Description
Helvolic acid is a mycotoxin originally isolated from A. fumigatus that has broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. At 4-16 mg/L, it acted synergistically with erythromycin (500-2,000 mg/L) in vitro on five multi-drug resistant strains of S. aureus. At 10 mg/kg/d, it reduced tumor growth and prolonged survival synergistically with cyclophosphamide (20 mg/kg/d) in a mouse model of sarcoma but had no effect when administered alone.
Uses
Helvolic acid is a mycotoxin with antibacterial activity.
Definition
ChEBI: A steroid C-21 acid having a 29-nordammarane skeleton substituted with an acetoxy group at C-16 and oxo groups at C-3 and -7, with double bonds at C-1, -17(20) and -24.
References
[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[2] PAMODA B RATNAWEERA. Helvolic acid, an antibacterial nortriterpenoid from a fungal endophyte, Xylaria sp. of orchid Anoectochilus setaceus endemic to Sri Lanka.[J]. Mycology, 2014, 5 1: 23-28. DOI: 10.1080/21501203.2014.892905
[3] LING QIN. In vitro synergistic antibacterial activities of helvolic acid on multi-drug resistant Staphylococcus aureus.[J]. Natural Product Research, 2009, 23 4: 309-318. DOI: 10.1080/14786410801972813
[4] JIAN-HUI XIAO. Synergistic antitumor efficacy of antibacterial helvolic acid from Cordyceps taii and cyclophosphamide in a tumor mouse model.[J]. Experimental Biology and Medicine, 2017, 242 2: 214-222. DOI: 10.1177/1535370216668051
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Preparation Products And Raw materials
Raw materials
Preparation Products
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Asperillum Ltm | 15920419256 | huangxishan13@foxmail.com | China | 177 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 10000 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4578 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4372 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
View Lastest Price from HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Helvolic acid
29400-42-8
|
$180.00-578.00 | 10g | TargetMol Chemicals Inc. |
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- Helvolic acid
29400-42-8
- $180.00-578.00
- TargetMol Chemicals Inc.
