(E,Z)-1-Methoxy-2-methyl-3- (trimethylsilyloxy)-1,3-pentadiene
- CAS No.
- 72486-93-2
- Chemical Name:
- (E,Z)-1-Methoxy-2-methyl-3- (trimethylsilyloxy)-1,3-pentadiene
- Synonyms
- TRANS-1-METHOXY-2-METHYL-3-(TRIMETHYLSI&;(1E 3Z)-1-METHOXY-2-METHYL-3-(TRIMETHYL&;1-Methoxy-2-methyl-3-(trimethylsilyloxy)-1,3-pentadiene;[(1-(2-Methoxy-1-methylvinyl)propenyloxy]trimethylsilan;(1e,3z)-1-methoxy-2-methyl-3-(trimethylsilyloxy)-1,3-pentadiene;(1e,3z)-1-methoxy-2-methyl-3-[(trimethylsilyl)oxy]-penta-1,3-diene;(1E,3Z)-1-Methoxy-2-methyl-3-(trimethylsilyloxy)-1,3-pentadiene;Silane, [[(1Z)-1-[(1E)-2-methoxy-1-methylethenyl]-1-propen-1-yl]oxy]trimethyl-;[(1-(2-Methoxy-1-methylvinyl)propenyloxy]trimethylsilan, (1E,3Z)-1-Methoxy-2-methyl-3-[(trimethylsilyl)oxy]-penta-1,3-diene
- CBNumber:
- CB2505347
- Molecular Formula:
- C10H20O2Si
- Molecular Weight:
- 200.35
- MDL Number:
- MFCD10567404
- MOL File:
- 72486-93-2.mol
- MSDS File:
- SDS
| Boiling point | 65 °C/6 mmHg (lit.) |
|---|---|
| Density | 0.899 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 178 °F |
| storage temp. | 2-8°C |
| InChI | 1S/C10H20O2Si/c1-7-10(9(2)8-11-3)12-13(4,5)6/h7-8H,1-6H3/b9-8+,10-7- |
| InChIKey | SSGAQVOLXCOJGN-AZRUORMVSA-N |
| SMILES | CO\C=C(C)\C(O[Si](C)(C)C)=C\C |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Acute Tox. 4 Oral |
(E,Z)-1-Methoxy-2-methyl-3- (trimethylsilyloxy)-1,3-pentadiene price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 640697 | (1E,3Z)-1-Methoxy-2-methyl-3-(trimethylsilyloxy)-1,3-pentadiene | 72486-93-2 | 1g | $173 | 2023-01-07 | Buy |
| American Custom Chemicals Corporation | ORS0000795 | (1E,3Z)-1-METHOXY-2-METHYL-3-(TRIMETHYLSILYLOXY)-1,3-PENTADIENE 95.00% | 72486-93-2 | 1G | $732.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0000795 | (1E,3Z)-1-METHOXY-2-METHYL-3-(TRIMETHYLSILYLOXY)-1,3-PENTADIENE 95.00% | 72486-93-2 | 5G | $1274 | 2021-12-16 | Buy |
(E,Z)-1-Methoxy-2-methyl-3- (trimethylsilyloxy)-1,3-pentadiene Chemical Properties,Uses,Production
Uses
(1E,3Z)-1-Methoxy-2-methyl-3-(trimethylsilyloxy)-1,3-pentadiene used as a reactant for:Preparation of migrastatin analog as cell migration inhibitor for treatment of tumor metastasis2Preparation of dihydropyridinones by chlorosilane-promoted aza-Diels-Alder addition3Synthesis on non-proteinogenic amino esters via stereoselective Lewis acid-catalyzed aza-Diels-Alder cycloaddition with conjugated (cyclo)dienes4
Uses
Danishefsky diene used as a reactant for:
Preparation of migrastatin analog as cell migration inhibitor for treatment of tumor metastasis
Preparation of dihydropyridinones by chlorosilane-promoted aza-Diels-Alder addition
Synthesis on non-proteinogenic amino esters via stereoselective Lewis acid-catalyzed aza-Diels-Alder cycloaddition with conjugated (cyclo)dienes
Synthesis
(1E,3Z)-1-Methoxy-2-Methyl-3-(triMethylsilyloxy)-1,3-pentadiene is prepared in multigram quantities as a colorless or slightly yellow liquid from 3- pentanone and ethyl formate via a three-step procedure (ca. 40% overall yield).
(E,Z)-1-Methoxy-2-methyl-3- (trimethylsilyloxy)-1,3-pentadiene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Supplier | Advantage |
|---|---|
| Energy Chemical | 61 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 57 |
| Sigma-Aldrich | 80 |
