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Wang-Yu non-directed C-H functionalization ligand

CAS No.
38609-76-6
Chemical Name:
Wang-Yu non-directed C-H functionalization ligand
Synonyms
3,5-Bis(trifluoromethyl)pyridin-2-ol;3,5-Bis(trifluoromethyl)-2(1H)-pyridinone;3,5-bis(trifluoromethyl)-2-hydroxypyridine;2(1H)-Pyridinone, 3,5-bis(trifluoromethyl)-;Wang-Yu non-directed C-H functionalization ligand
CBNumber:
CB25430600
Molecular Formula:
C7H3F6NO
Molecular Weight:
231.1
MDL Number:
MFCD28802532
MOL File:
38609-76-6.mol
MSDS File:
SDS
Last updated:2026-05-28 00:36:19

Wang-Yu non-directed C-H functionalization ligand Properties

Melting point 145 °C
storage temp. -20°C
form powder or crystals
Appearance White to off-white Solid
InChIKey IWSJDZMIJFAEBO-UHFFFAOYSA-N
SMILES FC(F)(F)c1c(ncc(c1)C(F)(F)F)O
UNSPSC Code 12352200
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  WGK 3
HS Code  2933399990
Storage Class 11 - Combustible Solids

Wang-Yu non-directed C-H functionalization ligand price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich ALD00606 Wang−Yu non-directed C−H functionalization ligand 95% 38609-76-6 250MG $375 2026-04-30 Buy
Biosynth NBA60976 3,5-Bis(trifluoromethyl)pyridin-2-ol 38609-76-6 50mg $337.5 2026-06-04 Buy
Biosynth NBA60976 3,5-Bis(trifluoromethyl)pyridin-2-ol 38609-76-6 0.5g $985.3 2026-06-04 Buy
Apolloscientific PC56190 3,5-Bis(trifluoromethyl)-2-hydroxypyridine ≥95% 38609-76-6 100mg $116 2026-06-04 Buy
Apolloscientific PC56190 3,5-Bis(trifluoromethyl)-2-hydroxypyridine ≥95% 38609-76-6 250mg $234 2026-06-04 Buy
Product number Packaging Price Buy
ALD00606 250MG $375 Buy
NBA60976 50mg $337.5 Buy
NBA60976 0.5g $985.3 Buy
PC56190 100mg $116 Buy
PC56190 250mg $234 Buy

Wang-Yu non-directed C-H functionalization ligand Chemical Properties, Uses, Production

Uses

This 2-pyridone ligand developed in the laboratory of Jin-Quan Yu binds to palladium and accelerates non-directed C-H functionalization. Developed for C-H olefination and carboxylation with arene as the limiting reagent, the Wang-Yu ligand enables diversification of drugs, synthetic intermediates, and other bioactive small molecules.

reaction suitability

reaction type: C-C Bond Formation
reagent type: catalyst
reaction type: C-H Activation

Wang-Yu non-directed C-H functionalization ligand Preparation Products And Raw materials

Raw materials

Preparation Products

Wang-Yu non-directed C-H functionalization ligand Suppliers

Global Suppliers ( 18)
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 6746 58
Tianjin heowns Biochemical Technology Co., Ltd. 400-6387771-6039 18920764717 sales@heowns.com China 24650 60
Shanghai Anyinuo Biomedical Technology Co., Ltd. 021-34625901 420970979@qq.com China 5982 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
Jiangsu aikang biomedical research and development co., LTD 025-58859352 17714375163 qzhang@aikonchem.com China 15525 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49299 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39796 58
Chengdu PEIP Pharmaceutical Technology Co., LTD. 028-61715638 18011352545 1242335275@qq.com China 473 58
Bide Pharmatech Ltd. 400-6005915 sales@picasso-e.com China 39662 58

Wang-Yu non-directed C-H functionalization ligand Spectrum

Wang-Yu non-directed C-H functionalization ligand 2(1H)-Pyridinone, 3,5-bis(trifluoromethyl)- 3,5-bis(trifluoromethyl)-2-hydroxypyridine 3,5-Bis(trifluoromethyl)pyridin-2-ol 3,5-Bis(trifluoromethyl)-2(1H)-pyridinone 38609-76-6