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4-(3-BROMOPHENYL)MORPHOLINE

4-(3-BROMOPHENYL)MORPHOLINE structure

CAS No.: 197846-82-5

Chemical Name:: 4-(3-BROMOPHENYL)MORPHOLINE

Synonyms: 4-(3-bromophenyl)morpholino;4-(3-BROMOPHENYL)MORPHOLINE;N-(3-BroMophenyl)Morpholine;1-(3-bromophenyl)-morpholine;Morpholine,4-(3-broMophenyl)-;4-(3-Bromophenyl)morpholine96%;1-BROMO-3-(4-MORPHOLINO)BENZENE;4-(3-Bromophenyl)morpholine 96%;1-Bromo-3-(morpholin-4-yl)benzene

CBNumber:: CB2664877

Molecular Formula:: C10H12BrNO

Molecular Weight:: 242.11

MDL Number:: MFCD04112585

MOL File:: 197846-82-5.mol

Last updated:2025-07-24 18:13:46

Product description	Number	Pack Size	Price
1-bromo-3-(4-morpholino)benzene Aldrich^CPR	CDS003639	250 mg	$73.1
4-(3-Bromophenyl)morpholine	B700298	10mg	$45
4-(3-Bromophenyl)morpholine	B700298	50mg	$60
4-(3-Bromophenyl)morpholine 96%	4H56-9-V8	1g	$24
4-(3-Bromophenyl)morpholine 96%	4H56-9-V8	25g	$392
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4-(3-BROMOPHENYL)MORPHOLINE Properties

Boiling point	341.1±37.0 °C(Predicted)
Density	1.433
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	4.02±0.40(Predicted)
form	liquid
color	Clear, brown
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H332-H335

Precautionary statements

P261-P280-P305+P351+P338

Hazard Codes

Xi,Xn

Risk Statements

Hazard Note

Irritant

HS Code

2934999090

NFPA 704

	0
2		0

4-(3-BROMOPHENYL)MORPHOLINE price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	CDS003639	1-bromo-3-(4-morpholino)benzene Aldrich^CPR		250 mg	$73.1	2025-07-31	Buy
TRC	B700298	4-(3-Bromophenyl)morpholine	197846-82-5	10mg	$45	2021-12-16	Buy
TRC	B700298	4-(3-Bromophenyl)morpholine	197846-82-5	50mg	$60	2021-12-16	Buy
SynQuest Laboratories	4H56-9-V8	4-(3-Bromophenyl)morpholine 96%	197846-82-5	1g	$24	2021-12-16	Buy
SynQuest Laboratories	4H56-9-V8	4-(3-Bromophenyl)morpholine 96%	197846-82-5	25g	$392	2021-12-16	Buy

Product number	Packaging	Price	Buy
CDS003639	250 mg	$73.1	Buy
B700298	10mg	$45	Buy
B700298	50mg	$60	Buy
4H56-9-V8	1g	$24	Buy
4H56-9-V8	25g	$392	Buy

4-(3-BROMOPHENYL)MORPHOLINE Chemical Properties,Uses,Production

Synthesis

110-91-8

108-36-1

197846-82-5

1,3-Dibromobenzene (50 g, 0.21 mol) and morpholine (15.89 mL, 0.19 mol) were used as raw materials, and both were added to the reaction flask with anhydrous toluene (200 mL) via a syringe under argon protection. After thorough mixing, R-BINAP (1.32 g, 0.0021 mol), palladium(0) dibenzylideneacetone (0.640 g, 0.006 mol) and DBU (25.8 mL, 0.17 mol) were added sequentially. The reaction mixture was stirred at 60 °C, followed by the addition of sodium tert-butoxide (30.55 g, 0.32 mol) and the reaction temperature was raised to 100 °C and continued overnight. Upon completion of the reaction, the suspension was diluted with ethyl acetate, filtered through diatomaceous earth and the organic phase was washed sequentially with water and brine. The organic phase was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography with the eluent ethyl acetate:hexane (1:1) to afford the target compound 4-(3-bromophenyl)morpholine as a yellow oil (36.5 g, 71% yield). Mass spectrometry (ES+) showed the molecular ion peak m/z 242 ([M+H]+).

References

[1] Patent: WO2011/144578, 2011, A1. Location in patent: Page/Page column 28
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 14, p. 5522 - 5537
[3] Tetrahedron, 2008, vol. 64, # 13, p. 2938 - 2950
[4] Patent: WO2011/144577, 2011, A1. Location in patent: Page/Page column 25-26

4-(3-BROMOPHENYL)MORPHOLINE Preparation Products And Raw materials

Raw materials

Calcium carbonate N,N-Dimethylformamide Sodium sulfate N,N-Diisopropylethylamine Ethyl acetate

2,2'-Dibromodiethyl ether 3-Bromoaniline Morpholine 1,3-Dibromobenzene 2-Bromoethanol

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Preparation Products

4-(3-BROMOPHENYL)MORPHOLINE Suppliers

Global( 95)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29799	58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.	+86-519-85525359 +86-15995072465	sales@xuanmingchem.com	China	907	58
Unipharm pharmaceutical industry Co., Ltd	536-8266195 +8613953676784	lee@unipharm-sd.com	China	1202	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3148	58
Golden Pharma Co., Limited	+undefined18958062155	sales@zjgoldpharm.com	China	5899	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33338	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.	58
Unipharm pharmaceutical industry Co., Ltd	58
Hangzhou Huarong Pharm Co., Ltd.	58
Golden Pharma Co., Limited	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58

View Lastest Price from 4-(3-BROMOPHENYL)MORPHOLINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-25	4-(3-BROMOPHENYL)MORPHOLINE 197846-82-5	US $1.00 / KG	1KG	99%	200kg	Career Henan Chemical Co

4-(3-BROMOPHENYL)MORPHOLINE
197846-82-5
US $1.00 / KG
99%
Career Henan Chemical Co

4-(3-BROMOPHENYL)MORPHOLINE Spectrum

4-(3-BROMOPHENYL)MORPHOLINE(197846-82-5)¹HNMR

197846-82-5(4-(3-BROMOPHENYL)MORPHOLINE)Related Search:

4-(4'-BROMOPHENYL)MORPHOLINE,N-(4-BROMOPHENYL)MORPHOLINE 4-(3-BROMOPHENYL)MORPHOLINE 2-BROMO-4-MORPHOLIN-4-YL-BENZALDEHYDE 4-BROMO-2-(N-MORPHOLINO)-BENZALDEHYDE 1-(3-Bromo-4-morpholin-4-ylphenyl)ethan-1-one, 4-(4-Acetyl-2-bromophenyl)morpholine

N-(2-bromophenyl)morpholine-4-sulfonamide N-(3-bromophenyl)morpholine-4-sulfonamide N-(2-amino-4-bromophenyl)morpholine-4-sulfonamide N-(4-bromophenyl)morpholine-4-sulfonamide RARECHEM AN KA 2211

RARECHEM AN KC 2208 SPIRO[2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE-5,5'-(9'-BROMO-1',2',4',4A',5',6'-HEXAHYDRO[1',4']OXAZINO[4',3'-A']QUINOLINE)] RARECHEM AN KA 2212 RARECHEM AN KD 2226 RARECHEM AN KD 2227

RARECHEM AN KC 2207 RARECHEM AN KB 2217 RARECHEM AN KB 2216

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1-Bromo-3-(morpholin-4-yl)benzene 4-(3-Bromophenyl)morpholine 96% 1-(3-bromophenyl)-morpholine N-(3-BroMophenyl)Morpholine Morpholine,4-(3-broMophenyl)- 4-(3-Bromophenyl)morpholine96% 4-(3-BROMOPHENYL)MORPHOLINE 1-BROMO-3-(4-MORPHOLINO)BENZENE 4-(3-bromophenyl)morpholino 197846-82-5 C10H12BrNO pharmacetical Aryl Organohalides Halides Phenyls & Phenyl-Het