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1-(2,6-DICHLOROBENZYL)PIPERAZINE

1-(2,6-DICHLOROBENZYL)PIPERAZINE Structure
1-(2,6-DICHLOROBENZYL)PIPERAZINE structure
CAS No.
102292-50-2
Chemical Name:
1-(2,6-DICHLOROBENZYL)PIPERAZINE
Synonyms
SBB009351;AKOS B014424;BAS 03082541;Oprea1_042275;Oprea1_177202;657832_ALDRICH;AG-670/40681823;BUTTPARK 36\08-57;ART-CHEM-BB B014424;TIMTEC-BB SBB009351
CBNumber:
CB2682167
Molecular Formula:
C11H14Cl2N2
Molecular Weight:
245.15
MDL Number:
MFCD02736281
MOL File:
102292-50-2.mol
MSDS File:
SDS
Last updated:2026-05-28 00:50:38
Product description Number Pack Size Price
1-(2,6-Dichlorobenzyl)piperazine 97% 657832 1g $55.1
1-(2,6-Dichlorobenzyl)piperazine 97% 657832 5g $184
1-(2,6-Dichlorobenzyl)piperazine >98% D67390 5g $70
1-(2,6-Dichlorobenzyl)piperazine >98% D67390 10g $140
1-(2,6-Dichlorobenzyl)piperazine 97% V146185 25G $230
More product size
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1-(2,6-DICHLOROBENZYL)PIPERAZINE Properties

Melting point 54-62 °C
Boiling point 332.4±37.0 °C(Predicted)
Density 1.252±0.06 g/cm3(Predicted)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form solid
pka 9.02±0.10(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C11H14Cl2N2/c12-10-2-1-3-11(13)9(10)8-15-6-4-14-5-7-15/h1-3,14H,4-8H2
InChIKey WQTPGHSKQDVCQQ-UHFFFAOYSA-N
SMILES N1(CC2=C(Cl)C=CC=C2Cl)CCNCC1
CAS DataBase Reference 102292-50-2(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
HazardClass  IRRITANT
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

1-(2,6-DICHLOROBENZYL)PIPERAZINE price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 657832 1-(2,6-Dichlorobenzyl)piperazine 97% 102292-50-2 1g $55.1 2023-06-20 Buy
Sigma-Aldrich 657832 1-(2,6-Dichlorobenzyl)piperazine 97% 102292-50-2 5g $184 2023-01-07 Buy
Synthonix D67390 1-(2,6-Dichlorobenzyl)piperazine >98% 102292-50-2 5g $70 2026-05-06 Buy
Synthonix D67390 1-(2,6-Dichlorobenzyl)piperazine >98% 102292-50-2 10g $140 2026-05-06 Buy
ACHEMBLOCK V146185 1-(2,6-Dichlorobenzyl)piperazine 97% 102292-50-2 25G $230 2026-05-27 Buy
Product number Packaging Price Buy
657832 1g $55.1 Buy
657832 5g $184 Buy
D67390 5g $70 Buy
D67390 10g $140 Buy
V146185 25G $230 Buy

1-(2,6-DICHLOROBENZYL)PIPERAZINE Chemical Properties,Uses,Production

Synthesis

Piperazine

110-85-0

2,6-Dichlorobenzyl bromide

20443-98-5

1-(2,6-DICHLOROBENZYL)PIPERAZINE

102292-50-2

1. Dissolve piperazine (112 mmol, 6.0 eq.) in THF (180 mL) at 0 °C to prepare a solution. 2. 2,6-dichlorobenzyl bromide (4.5 g, 18.8 mmol) was dissolved in THF (20 mL) to prepare a solution and slowly added dropwise to the THF solution of piperazine over 10 minutes. 3. After the dropwise addition was completed, the reaction mixture was slowly warmed to room temperature and stirred continuously for 24 hours. 4. Upon completion of the reaction, the THF solvent was removed by distillation under reduced pressure. 5. The crude product was resuspended in a mixture of dichloromethane (DCM) and water and extracted twice with DCM. 6. The organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated. 7. The crude product was purified using combiflash fast chromatography eluting with a gradient of 0 to 20% methanol in DCM to afford the target compound 1-(2,6-dichlorobenzyl)piperazine (2.3 g, 50% yield). 8. The structure of the product was confirmed by 1H NMR, 13C NMR and HRMS. 1H NMR (400 MHz, methanol-d4) δ 7.62-7.30 (m, 2H), 7.23 (dd, J = 8.7, 7.4 Hz, 1H), 3.74 (s, 2H), 2.92-2.69 (m, 4H), 2.56 (t, J = 4.9 Hz, 4H). 13C NMR (101 MHz, MeOD) δ 136.76, 133.67, 129.18, 128.24, 56.55, 53.41, 44.95. HRMS (m/z): [M+] calculated value C11H14Cl2N2 245.15, measured value 245.06.

References

[1] Patent: WO2015/184349, 2015, A2. Location in patent: Paragraph 0221
[2] Patent: WO2016/176338, 2016, A1. Location in patent: Paragraph 0132
[3] European Journal of Medicinal Chemistry, 2019, vol. 161, p. 22 - 38

1-(2,6-DICHLOROBENZYL)PIPERAZINE synthesis

110-85-0
2014-83-7
102292-50-2
Synthesis of 1-(2,6-DICHLOROBENZYL)PIPERAZINE from Piperazine and 2,6-Dichlorobenzyl chloride

1-(2,6-DICHLOROBENZYL)PIPERAZINE Preparation Products And Raw materials

Raw materials

2,6-Dichlorobenzyl chloride 2,6-Dichlorobenzyl bromide Piperazine

Preparation Products

1-(2,6-DICHLOROBENZYL)PIPERAZINE Suppliers

Global( 90)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
Alfa Chemistry 		+1-5166625404; Info@alfa-chemistry.com United States 20405 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Labnetwork lnc. 		58
Alfa Chemistry 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58

View Lastest Price from 1-(2,6-DICHLOROBENZYL)PIPERAZINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(2,6-DICHLOROBENZYL)PIPERAZINE pictures 2020-01-09 1-(2,6-DICHLOROBENZYL)PIPERAZINE
102292-50-2
 US $1.00 / KG 1KG 99% 100KG Career Henan Chemical Co

1-(2,6-DICHLOROBENZYL)PIPERAZINE Spectrum

1-(2,6-DICHLOROBENZYL)PIPERAZINE(102292-50-2)1HNMR

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TIMTEC-BB SBB009351 AKOS B014424 BUTTPARK 36\08-57 ART-CHEM-BB B014424 1-(2,6-DICHLORO-BENZYL)-PIERPAZINE 1-(2,6-DICHLOROBENZYL)-PIPERAZINE >98% 1-(2,6-DICHLOROBENZYL)PIPERAZINE 1-(2,6-dichlorobenzyl)piperazine(SALTDATA: FREE) 6-Dichloro-benzyl)-pierpazine 1-[(2,6-dichlorophenyl)methyl]piperazine 657832_ALDRICH AG-670/40681823 BAS 03082541 Oprea1_042275 Oprea1_177202 SBB009351 Piperazine, 1-[(2,6-dichlorophenyl)methyl]- Dextropropoxyphene Hydrochloride Impurity 12 102292-50-2 Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Piperazines Piperaizine Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Piperazines PiperazinesHeterocyclic Building Blocks