5,7-DIHYDROXY-3-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE
- CAS No.
- 20869-95-8
- Chemical Name:
- 5,7-DIHYDROXY-3-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE
- Synonyms
- ERMANIN;5,7-DIHYDROXY-3,4'-DIMETHOXYFLAVONE;NSC 31882;Ermanin, 10 mM in DMSO;3,4'-Dimethoxykaempferol;KAEMPFEROL-3,4'-DIMETHYL ETHER;Kaempferol 3,4'-di-O-methyl ether;3,4'-DIMETHOXY-5,7-DIHYDROXYFLAVONE;5,7-dihydroxy-3-methoxy-2-(4-methoxyphenyl)-4-benzopyrone;5,7-DIHYDROXY-3-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE
- CBNumber:
- CB2682172
- Molecular Formula:
- C17H14O6
- Molecular Weight:
- 314.29
- MDL Number:
- MFCD00017440
- MOL File:
- 20869-95-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ermanin ≥98% | 37535 | 5mg | $40 |
| Ermanin ≥98% | 37535 | 10mg | $76 |
| Ermanin ≥98% | 37535 | 25mg | $179 |
| Ermanin ≥98% | 37535 | 50mg | $315 |
| Ermanin ≥98% | 380234 | 10mg | $638 |
| Melting point | 234 °C |
|---|---|
| Boiling point | 552.0±50.0 °C(Predicted) |
| Density | 1.46±0.1 g/cm3(Predicted) |
| solubility |
DMF: 20 mg/ml DMSO: 15 mg/ml |
| pka | 6.32±0.40(Predicted) |
| LogP | 2.400 (est) |
| FDA UNII | 850D90YJN3 |
5,7-DIHYDROXY-3-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 37535 | Ermanin ≥98% | 20869-95-8 | 5mg | $40 | 2026-04-30 | Buy |
| Cayman Chemical | 37535 | Ermanin ≥98% | 20869-95-8 | 10mg | $76 | 2026-04-30 | Buy |
| Cayman Chemical | 37535 | Ermanin ≥98% | 20869-95-8 | 25mg | $179 | 2026-04-30 | Buy |
| Cayman Chemical | 37535 | Ermanin ≥98% | 20869-95-8 | 50mg | $315 | 2026-04-30 | Buy |
| Usbiological | 380234 | Ermanin ≥98% | 20869-95-8 | 10mg | $638 | 2026-06-03 | Buy |
5,7-DIHYDROXY-3-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Chemical Properties,Uses,Production
Uses
Ermanin is a useful research chemical used in HIV-1 integrase inhibition. Ermanin exhibits actioxidant properties against peroxyl and hydroxyl radicals.
Definition
ChEBI: 3,4'-dimethylkaempferol is a dimethoxyflavone that is kaempferol in which the hydroxy groups at position 3 and 4' have been replaced by methoxy groups. It is a component of bee glue and isolated from several plant species including Tanacetum microphyllum. It has a role as an anti-inflammatory agent, an antimycobacterial drug, an apoptosis inducer, an antineoplastic agent and a plant metabolite. It is a dihydroxyflavone and a dimethoxyflavone. It is functionally related to a kaempferol.
IC 50
iNOS; Bacterial; COX-2
References
[1] QIONG DING . The critical role of glutathione redox homeostasis towards oxidation in ermanin-induced melanogenesis[J]. Free Radical Biology and Medicine, 2021, 176: Pages 392-405. DOI: 10.1016/j.freeradbiomed.2021.09.017
[2] JOSÉ ANTONIO GUERRA. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids isolated from Tanacetum microphyllum[J]. International immunopharmacology, 2006, 6 11: Pages 1723-1728. DOI: 10.1016/j.intimp.2006.08.012
[3] NADINE DE MEYER. 4’-Hydroxy-3-methoxyflavones with potent antipicornavirus activity[J]. Journal of Medicinal Chemistry, 1991, 34 2: 736-746. DOI: 10.1021/jm00106a039
5,7-DIHYDROXY-3-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
5,7-DIHYDROXY-3-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +86-18080483897 | sales@biopurify.com | China | 4616 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89667 | 60 |
| Shanghai Yihe Biological Technology Co., Ltd. | 021-68882955 17721395025 | 2423903095@qq.com | China | 5000 | 58 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 18080489829@163.com | China | 8379 | 60 |
