4-Benzyloxyphenylacetic acid methyl ester
- CAS No.
- 68641-16-7
- Chemical Name:
- 4-Benzyloxyphenylacetic acid methyl ester
- Synonyms
- methyl 2-(4-(benzyloxy)phenyl)acetate;METHYL 4-BENZYLOXYPHENYLACETATE;methyl 2-(4-phenylmethoxyphenyl)acetate;4-Benzyloxyphenylacetic acid methyl ester;4-Benzyloxyphenylacetic Acid Methyl Ester,>97%;Benzeneacetic acid, 4-(phenylmethoxy)-, methyl ester
- CBNumber:
- CB2698384
- Molecular Formula:
- C16H16O3
- Molecular Weight:
- 256.3
- MDL Number:
- MFCD00157061
- MOL File:
- 68641-16-7.mol
- MSDS File:
- SDS
| Melting point | 53 °C |
|---|---|
| Boiling point | 375.0±22.0 °C(Predicted) |
| Density | 1.129±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| Appearance | White to light yellow Solid |
| CAS DataBase Reference | 68641-16-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H400 |
| Precautionary statements | P273-P391-P501 |
4-Benzyloxyphenylacetic acid methyl ester price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 69317 | METHYL 4-BENZYLOXYPHENYLACETATE 95% | 68641-16-7 | 5G | $17 | 2026-04-30 | Buy |
| AstaTech | 69317 | METHYL 4-BENZYLOXYPHENYLACETATE 95% | 68641-16-7 | 10G | $33 | 2026-04-30 | Buy |
| AstaTech | 69317 | METHYL 4-BENZYLOXYPHENYLACETATE 95% | 68641-16-7 | 25G | $59 | 2026-04-30 | Buy |
| Biosynth | FB70559 | 4-(Benzyloxyphenyl)acetic acid methyl ester | 68641-16-7 | 10g | $150 | 2026-06-04 | Buy |
| Biosynth | FB70559 | 4-(Benzyloxyphenyl)acetic acid methyl ester | 68641-16-7 | 25g | $150 | 2026-06-04 | Buy |
4-Benzyloxyphenylacetic acid methyl ester Chemical Properties, Uses, Production
Synthesis
14199-15-6
100-44-7
68641-16-7
To a suspension of acetone (50 mL) containing potassium carbonate (K2CO3, 20.7 g, 150 mmol) was sequentially added methyl 4-hydroxyphenylacetate (5.0 g, 30 mmol) and benzyl chloride (10.4 mL, 90 mmol). The reaction mixture was heated to reflux for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature, filtered to remove insoluble solids and the filtrate was concentrated. The residue was purified by silica gel column chromatography with 10% ethyl acetate/hexane as eluent to afford methyl 4-benzyloxyphenylacetate (7.7 g, 100% yield) as a white solid. Its 1H NMR (300 MHz, CDCl3) data were as follows: δ 7.40 (m, 5H), 7.21 (d, J = 6.6 Hz, 2H), 6.95 (d, J = 6.6 Hz, 2H), 5.05 (s, 2H), 3.70 (s, 3H), 3.59 (s, 2H).
References
[1] Patent: EP1218005, 2004, B1. Location in patent: Page 26
[2] Patent: WO2014/69963, 2014, A1. Location in patent: Paragraph 464-466
[3] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 4, p. 1209 - 1213
[4] Journal of Organic Chemistry, 1982, vol. 47, # 15, p. 2846 - 2851
[5] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 4, p. 525 - 528
4-Benzyloxyphenylacetic acid methyl ester Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Beijing Taiya Jie Technology Development Co., Ltd. | 021-33690831-8001 13552411790;18616022633 | postmaster@tyjchem.cn | China | 1541 | 55 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Beijing FYF Chemicals Co., Ltd | 010-57903446 15869909019 | 168931144@qq.com | China | 2876 | 58 |
View Latest Price from 4-Benzyloxyphenylacetic acid methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-01-15 | methyl2-(4-phenylmethoxyphenyl)acetate
68641-16-7
|
1KG | 99.2% | 100 tons | Honest Joy Holdings Limited | ||
 |
2020-03-06 | 4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER
68641-16-7
|
$8.00 | 1g | ≥98% | Career Henan Chemical Co |
-
- methyl2-(4-phenylmethoxyphenyl)acetate
68641-16-7
- $0.00
- 99.2%
- Honest Joy Holdings Limited
-
- 4-BENZYLOXYPHENYLACETIC ACID METHYL ESTER
68641-16-7
- $8.00
- ≥98%
- Career Henan Chemical Co
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