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Eptaplatin

Eptaplatin Structure
Eptaplatin structure
CAS No.
146665-77-2
Chemical Name:
Eptaplatin
Synonyms
heptaplatin;SUNPLA;SKI 2053R;EPTAPLATIN;(SP-4-2)-[(4R,5R;EPOXYPROGESTERONE;Eptaplatin, >=98%;EPTAPLATIN, SUNPLA;Eptaplatin(SKI-2053R);Eptaplatin(Heptaplatin)
CBNumber:
CB2717771
Molecular Formula:
C11H20N2O6Pt
Molecular Weight:
471.36
MDL Number:
MFCD00931412
MOL File:
146665-77-2.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06
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Eptaplatin Properties

Melting point 43-49°C
storage temp. Refrigerator, Under Inert Atmosphere
solubility DMSO (Slightly), Water (Slightly, Heated)
form Solid
color White to Off-White
FDA UNII 1352HON1DH

Eptaplatin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-E591500-5MG Eptaplatin 146665-77-2 5mg $176 2026-06-03 Buy
TRC TRC-E591500-10MG Eptaplatin 146665-77-2 10mg $275 2026-06-03 Buy
Biosynth FE22772 Eptaplatin 146665-77-2 25mg $285.5 2026-06-04 Buy
Biosynth FE22772 Eptaplatin 146665-77-2 50mg $389.5 2026-06-04 Buy
Biosynth FE22772 Eptaplatin 146665-77-2 100mg $649 2026-06-04 Buy
Product number Packaging Price Buy
TRC-E591500-5MG 5mg $176 Buy
TRC-E591500-10MG 10mg $275 Buy
FE22772 25mg $285.5 Buy
FE22772 50mg $389.5 Buy
FE22772 100mg $649 Buy

Eptaplatin Chemical Properties, Uses, Production

Description

SKI-2053R was launched in Korea for the treatment of patients with advanced gastric adenocarcinoma. It is a third generation platinum complex alkylating agent with less nephrotoxicity than cisplatin. In in vitro experiments, SKI-2053R was highly active against various cell lines including cisplatinresistant tumor cell lines. In mice implanted with L1210 cells, SKI-2053R showed activity comparable or superior to cisplatin or carboplatin. In mice implanted s.c. with human tumor xenograft KATO III (stomach adenocarcinoma), SKI-2053R achieved growth-inhibition rates comparable with those of cisplatin. General pharmacological studies in animals did not display any severe adverse effects on the different systems at antitumour doses. Pharmacokinetic studies after a single iv administration in rats demonstrated that the compound was extensively and rapidly distributed into all tissues except the CNS. In patients with unresectable or metastatic gastric adenocarcinoma, SKI-2053R was active without significant hematological toxicity. Phase III trials with SKI-2053R are currently ongoing for the treatment of various other cancers including lung, head and neck.

Chemical Properties

White Crystalline Powder

Originator

SK Pharma (Korea)

Uses

A coordination compound for treatment of cervix cancer.

brand name

Sunpla

Pharmaceutical Applications

heptaplatin is further examples of platinum-based agents being used in China and South Korea, respectively. Heptaplatin is used in South Korea to treat gastric cancer. It show the typical side effects such as myelosuppression and mild hepatotoxicity. its success is limited and has not led to approval in the EU or by the FDA.

Eptaplatin Preparation Products And Raw materials

Raw materials

Preparation Products

Eptaplatin Suppliers

Global Suppliers ( 102)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6742 52
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
HBCChem, Inc. +1-510-219-6317 sales@hbcchem.com United States 10628 60
Watson Biotechnology Co.,Ltd 027-59207879 1972026995 18140587686 sales@3600chem.com China 4187 55
Shanghai Haozhixiang Biotechnology Co., Ltd 526763801 13301653310 526763801@qq.com China 7982 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Chembest Research Laboratories Limited 61
Wuhan Chemwish Technology Co., Ltd 56
LGM Pharma 70
Chemsky（shanghai）International Co.,Ltd. 50
XiaoGan ShenYuan ChemPharm co,ltd 52
BOC Sciences 65
HBCChem, Inc. 60
Watson Biotechnology Co.,Ltd 55
Shanghai Haozhixiang Biotechnology Co., Ltd 55

View Latest Price from Eptaplatin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Eptaplatin pictures 2026-09-16 Eptaplatin
146665-77-2
 1g 98%-102% 100g WUHAN FORTUNA CHEMICAL CO., LTD
Eptaplatin pictures 2021-07-13 Eptaplatin
146665-77-2
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
Eptaplatin pictures 2021-07-09 Eptaplatin
146665-77-2
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
  • Eptaplatin pictures
  • Eptaplatin
    146665-77-2
  • $0.00
  • 98%-102%
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Eptaplatin pictures
  • Eptaplatin
    146665-77-2
  • $10.00-15.00
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • Eptaplatin pictures
  • Eptaplatin
    146665-77-2
  • $10.00-15.00
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd

146665-77-2 (Eptaplatin) Related Search:

Dichloro(ethylenediamine)platinum(II) Cisplatin Carboplatin cis-Diamminediiodoplatinum Nedaplatin
LOBAPLATIN Picoplatin Satraplatin (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate Dibromo(1,5-cyclooctadiene)platinum(II)
(4R,5R)-4,5-Bis(aminomethyl)-2-isopropyl-1,3-dioxolane Platinum Malonic acid Eptaplatin

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SUNPLA [sp-4-2-[4r-(2a,4a,5b)]]-[2-(1-methylethyl)-1,3-dioxolane-4,5-dimethanamine-n,n'][propanedioato(2-)-o,o']-platinum EPTAPLATIN SKI 2053R EPOXYPROGESTERONE (SP-4-2)-[(4R,5R)-2-ISOPROPYL-1,3-DIOXOLANE-4,5-BIS(METHANAMINE)-N,N''][PROPANEDIOATO(2-)-O,O'']PLATINUM (SP-4-2)-[(4R,5R)-2-(1-Methylethyl-1,3-dioxolane 4,5-dimethanamine-kN4,kN5][propanedioato(2-)-kO1,kO3]platinum cis-[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane](malonate)platinum(II) (SP-4-2)-[(4R,5R)-2-Isopropyl-1,3-dioxolane-4,5- EPTAPLATIN, SUNPLA Eptaplatin(Heptaplatin) Eptaplatin(SKI-2053R) Eptaplatin, >=98% (SP-4-2)-[(4R,5R cis-[(4R,5R)-2-Isopropyl-1,3-dioxolane-4,5-bis(methylamine)-N,N'][malonato(2-)-O,O']platinum Cis-(1,3-malanato)-[(4R,5R)-4,5-bis(aminomethyl)-2isopropyl-1,3-dioxolane]platinum(II) cis-{Pt(II)[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane](3-acetoxyl-cyclobutane-1,1-dicarboxylato)} 9-propan-2-yl-8,10-dioxa-3,5-diaza-4$l^{4}-platinabicyclo[5.3.0]deca-3,4-diene cis-[2-Isopropyl-1,3-dioxolane-4,5-bis(methylamine)-N,N][malonato(2-)-O,O]platinum Heptaplatin (SKI-2053R) Eptaplatin, Heptaplatin, Sunpla heptaplatin 146665-77-2 C11H20N2O6Pt C8H18N2O2C3H2O4Pt C11H16N2O6Pt Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Heterocyclic Compounds Anticancer