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TAK-020

TAK-020 Structure
TAK-020 structure
CAS No.
1627603-21-7
Chemical Name:
TAK-020
Synonyms
TAK-020;TAK-020, 10 mM in DMSO;3H-1,2,4-Triazol-3-one, 1,2-dihydro-5-[1-[[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]oxy]-3-isoquinolinyl]-
CBNumber:
CB29709863
Molecular Formula:
C18H17N5O3
Molecular Weight:
351.36
MDL Number:
MOL File:
1627603-21-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:31
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TAK-020 Properties

Density 1.47±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 16.67 mg/mL (47.44 mM; ultrasonic and warming and heat to 60°C)
form Solid
pka 6.41±0.20(Predicted)
color White to off-white
FDA UNII U3T5W003VP

TAK-020 Chemical Properties,Uses,Production

Uses

TAK-020 is a covalent Btk inhibitor, which becomes the clinical candidate.

References

[1] Sabat M, et al. Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 (S)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, by Fragment-Based Drug Design. J Med Chem. 2021 Sep 9;64(17):12893-12902. DOI:10.1021/acs.jmedchem.1c01026

TAK-020 Preparation Products And Raw materials

Raw materials

Preparation Products

TAK-020 Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3505 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 86249 60
Chunchuang (Wuhan) Technology Co., Ltd 15727060112 yutianchun2007@126.com China 9858 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24960 58
Suzhou Haiben Pharmaceutical Co., Ltd 19353112242 1816280386@qq.com China 8045 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11972 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 5001 58
Suzhou Meidi Senuo Pharmaceutical Technology Co., Ltd. 13771642864 snhuyu_2008@126.com China 1190 58
Nantong Hanfang Biotechnology Co. , Ltd. hanfangpharma@126.com; 18616537568 hanfangpharma@126.com China 25801 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9835 58
Supplier Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Chunchuang (Wuhan) Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
Suzhou Haiben Pharmaceutical Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
Suzhou Meidi Senuo Pharmaceutical Technology Co., Ltd. 58
Nantong Hanfang Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58

TAK-020 Spectrum

TAK-020(1627603-21-7)1HNMR

1627603-21-7(TAK-020)Related Search:

TAK-659 (hydrochloride) Tak-715 N-Des(aMinocarbonyl) AZ-TAK1 Inhibitor
TAK-020 3H-1,2,4-Triazol-3-one, 1,2-dihydro-5-[1-[[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]oxy]-3-isoquinolinyl]- TAK-020, 10 mM in DMSO 1627603-21-7