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3,4-Dimethoxybenzyl bromide

3,4-Dimethoxybenzyl bromide Structure
3,4-Dimethoxybenzyl bromide structure
CAS No.
21852-32-4
Chemical Name:
3,4-Dimethoxybenzyl bromide
Synonyms
4-(BroMoMethyl)-1,2-diMethoxybenzene;Veratryl bromide;3,4-Dimethoxybenzyl bromide;Pinaverium Bromide Impurity 22;Toluene, α-bromo-3,4-dimethoxy-;4-(Bromomethyl)-1,2-Dimethoxybenzen;Benzene, 4-(broMoMethyl)-1,2-diMethoxy-;3,4-DiMethoxybenzyl BroMide Discontinued due to stability
CBNumber:
CB31010256
Molecular Formula:
C9H11BrO2
Molecular Weight:
231.09
MDL Number:
MFCD09833606
MOL File:
21852-32-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:51:31
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3,4-Dimethoxybenzyl bromide Properties

Melting point 56-58℃
Boiling point 273℃
Density 1.384
Flash point 116℃
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility CDCl3;
form Solid
color Off-white
InChI InChI=1S/C9H11BrO2/c1-11-8-4-3-7(6-10)5-9(8)12-2/h3-5H,6H2,1-2H3
InChIKey AKPSLMUFDIXDJJ-UHFFFAOYSA-N
SMILES C1(OC)=CC=C(CBr)C=C1OC

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H335-H301
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501

3,4-Dimethoxybenzyl bromide price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FD22198 3,4-Dimethoxybenzyl bromide 21852-32-4 0.5g $163.27 2026-06-04 Buy
Biosynth FD22198 3,4-Dimethoxybenzyl bromide 21852-32-4 1g $244.9 2026-06-04 Buy
Biosynth FD22198 3,4-Dimethoxybenzyl bromide 21852-32-4 2g $380.98 2026-06-04 Buy
Biosynth FD22198 3,4-Dimethoxybenzyl bromide 21852-32-4 5g $725.6 2026-06-04 Buy
Biosynth FD22198 3,4-Dimethoxybenzyl bromide 21852-32-4 10g $997.8 2026-06-04 Buy
Product number Packaging Price Buy
FD22198 0.5g $163.27 Buy
FD22198 1g $244.9 Buy
FD22198 2g $380.98 Buy
FD22198 5g $725.6 Buy
FD22198 10g $997.8 Buy

3,4-Dimethoxybenzyl bromide Chemical Properties,Uses,Production

Uses

3,4-DIMETHOXYBENZYL BROMIDE used in the dimethoxybenzyl alkylations.

Uses

Reagent used in the dimethoxybenzyl alkylations.

Preparation

3,4-Dimethoxybenzyl Bromide is synthesized from commercially available 3,4-dimethoxybenzyl alcohol and PBr3 or HBr.[2-3]

General Description

3,4-Dimethoxybenzyl Bromide (DMBBr) is used as a reagent for introduction of 3,4-dimethoxybenzyl protecting group, which can be cleaved selectively under conditions of benzylic oxidation.[1]

Synthesis

3,4-Dimethoxybenzyl alcohol

93-03-8

3,4-DIMETHOXYBENZYL BROMIDE

21852-32-4

The general procedure for the synthesis of 3,4-dimethoxybenzyl bromide from 3,4-dimethoxybenzyl alcohol: 3,4-dimethoxybenzyl alcohol (1 mmol) was dissolved in anhydrous benzene (15 mL) under anhydrous conditions, phosphorus tribromide (0.5 mL) was added and the reaction was stirred at room temperature. Upon completion of the reaction, the target product 3,4-dimethoxybenzyl bromide was obtained in quantitative yield by conventional post-treatment steps.

storage

3,4-Dimethoxybenzyl Bromide reactions are usually carried out in polar solvents such as THF or DMF. The reagent is quite unstable and is best prepared fresh or stored at low temperature under nitrogen. It is a lachrymator.

References

1. (a) Horita, K.; Yoshioka, T.; Tanaka, T.; Oikawa, Y.; Yonemitsu, O. T 1986, 42, 3021. (b) Oikawa, Y.; Tanaka, T.; Horita, K.; Yoshioka, T.; Yonemitsu, O. TL 1984, 25, 5393.
2. Lakhlifi, T.; Sedqui, A.; Laude, B.; Dinh An, N.; Vebrel, J. CJC 1991, 69, 1156.
3. Coote, S. J.; Davies, S. G.; Middlemiss, D.; Naylor, A. JCS(P1) 1989, 2223.

3,4-Dimethoxybenzyl bromide Preparation Products And Raw materials

Raw materials

3,4-Dimethoxybenzyl alcohol Phosphorus tribromide Benzene

Preparation Products

Veratrylamine 4-trans-propenylveratrole Benzene, 1,1'-(1,2-ethanediyl)bis[3,4-diMethoxy- α-Tosyl-(3,4-dimethoxybenzyl)isocyanide 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)-3-((3,4-dimethoxyphenyl )methyl)dihydro-, (3R-trans)-

3,4-Dimethoxybenzyl bromide Suppliers

Global( 123)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangsu Chromene New Material Technology Co., Ltd 15358977508 lengyan1114@126.com China 21 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Beijing Donghualituo Techonlogy Development Co.,Ltd. 010-88425576 sales@dhltchem.com China 793 59
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Shanghai yirong biology science and technology co., ltd 18049974220 3060526242@qq.com China 999 60
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2853 52
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Supplier Advantage
Jiangsu Chromene New Material Technology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Beijing Donghualituo Techonlogy Development Co.,Ltd. 59
Adamas Reagent, Ltd. 59
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky (shanghai) International Co.,Ltd 60
Shanghai yirong biology science and technology co., ltd 60
Hangzhou Sage Chemical Co., Ltd. 58
Shanghai Witofly Chemical Co.,Ltd 52
Shanghai Raise Chemical Technology Co.,Ltd 55

View Lastest Price from 3,4-Dimethoxybenzyl bromide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4-DIMETHOXYBENZYL BROMIDE pictures 2020-02-05 3,4-DIMETHOXYBENZYL BROMIDE
21852-32-4
 $3.00 1KG 98% 100KG Career Henan Chemical Co

3,4-Dimethoxybenzyl bromide Spectrum

3,4-DIMETHOXYBENZYL BROMIDE(21852-32-4)1HNMR

21852-32-4(3,4-Dimethoxybenzyl bromide)Related Search:

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3,4-DiMethoxybenzyl BroMide Discontinued due to stability Veratryl bromide Benzene, 4-(broMoMethyl)-1,2-diMethoxy- Toluene, α-bromo-3,4-dimethoxy- 4-(Bromomethyl)-1,2-Dimethoxybenzen Pinaverium Bromide Impurity 22 4-(BroMoMethyl)-1,2-diMethoxybenzene 3,4-Dimethoxybenzyl bromide 21852-32-4 Aromatics Miscellaneous Reagents