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ChemicalBook >> CAS DataBase List >>2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)-

2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)-

2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)- Structure
2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)- structure
CAS No.
2495096-26-7
Chemical Name:
2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)-
Synonyms
Lartesertib;ATM Inhibitor-5;Lartesertib (M4076);ATM Inhibitor-5|||M4076;2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)-;(1S)-8-(1,3-Dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-2H-imidazo[4,5-c]quinolin-2-one (ACI)
CBNumber:
CB310258182
Molecular Formula:
C23H21FN6O3
Molecular Weight:
448.46
MDL Number:
MOL File:
2495096-26-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:53:41
Request For Quotation

2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)- Properties

Boiling point 589.3±60.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka 3.51±0.10(Predicted)
form Solid
color White to off-white
FDA UNII KL7B6D38VC

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0534879 Lartesertib 99.94% 2495096-26-7 1mg $173 2026-06-04 Buy
ChemScene CS-0534879 Lartesertib 99.94% 2495096-26-7 5mg $433 2026-06-04 Buy
ChemScene CS-0534879 Lartesertib 99.94% 2495096-26-7 10mg $737 2026-06-04 Buy
ChemScene CS-0534879 Lartesertib 99.94% 2495096-26-7 25mg $1462 2026-06-04 Buy
ChemScene CS-0534879 Lartesertib 99.94% 2495096-26-7 50mg $2383 2026-06-04 Buy
Product number Packaging Price Buy
CS-0534879 1mg $173 Buy
CS-0534879 5mg $433 Buy
CS-0534879 10mg $737 Buy
CS-0534879 25mg $1462 Buy
CS-0534879 50mg $2383 Buy

2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)- Chemical Properties, Uses, Production

Uses

Lartesertib (M4076) is a potent inhibitor of serine/threonine protein kinase ATM (extracted from patent WO2022058351A1)[1].

Biological Activity

ATM Inhibitor-5 [formula (1)] is a potent inhibitor of serine/threonine protein kinase ATM (extracted from patent WO2022058351A1)[1].

IC 50

ATM

References

[1]. Alessandra AMBRUOSI, et al. Pharmaceutical preparation. WO2022058351A1.

2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)- Preparation Products And Raw materials

Raw materials

Preparation Products

2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)- Suppliers

Global Suppliers ( 15)
Supplier Tel Email Country ProdList Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 sales@sun-shinechem.com China 1197 64
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Beijing Solarbio Science & Tecnology Co., Ltd. 17801761073 18101056239 3193328036@qq.com China 28150 68
Nantong Hi-Future Biotechnology Co., Ltd +86-0513; 18051384581 sales@chemhifuture.com China 3075 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-025-66113011 15955137747 cb5@aikonchem.com China 10354 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 4000862158 18117107507 vip@med-life.cn China 4999 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
Qingdao Haizhi Weiyuan Biotechnology Co., Ltd. 18317699790 18317699790 l202008112023@163.com China 7733 58
Supplier Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
Shanghai YuanYe Biotechnology Co., Ltd. 60
Beijing Solarbio Science & Tecnology Co., Ltd. 68
Nantong Hi-Future Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
Shanghai Amole Biotechnology Co., Ltd. 58
Qingdao Haizhi Weiyuan Biotechnology Co., Ltd. 58

2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)- Spectrum

2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)-(2495096-26-7)1HNMR

2495096-26-7 (2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)-) Related Search:

Benzonitrile, 4-[2,3-dihydro-7-methoxy-3-methyl-8-(1-methyl-1H-pyrazol-4-yl)-2-oxo-1H-imidazo[4,5-c]quinolin-1-yl]-3-fluoro- 2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)- 2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl- 2'3'-cGAMP Carbonyl cyanide 3-chlorophenylhydrazone
c[A(2',5')pS[Rp]-A(3',5')pS[Rp]] / Rp,Rp-2'3'-c-diAMPSS

1of2

2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)- ATM Inhibitor-5 ATM Inhibitor-5|||M4076 Lartesertib (M4076) Lartesertib (1S)-8-(1,3-Dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-2H-imidazo[4,5-c]quinolin-2-one (ACI) 2495096-26-7