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ChemicalBook >> CAS DataBase List >>L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Structure
L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- structure
CAS No.
2306389-02-4
Chemical Name:
L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
Synonyms
JYS005;VH032-C6-NH-Boc;L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
CBNumber:
CB312230397
Molecular Formula:
C35H53N5O6S
Molecular Weight:
671.89
MDL Number:
MOL File:
2306389-02-4.mol
Last updated:2025-04-17 18:22:24
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L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Properties

Boiling point 896.6±65.0 °C(Predicted)
Density 1.173±0.06 g/cm3(Predicted)
pka 12.94±0.46(Predicted)

L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Chemical Properties, Uses, Production

Uses

VH032-C6-NH-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C6-NH-Boc will remove the protecting group under acidic conditions and be directly used in PROTAC molecule synthesis. VH032-C6-NH-Boc is a key intermediate in the synthesis of PROTAC based on VHL ligand.

L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Preparation Products And Raw materials

Raw materials

Preparation Products

L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7917 65
CR Corporation Limited fred.wen@crcorporation.cn China 8642 58
Suzhou Haiben Pharmaceutical Co., Ltd 19353112242 1816280386@qq.com China 8041 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Changsha Fuzhen Biotechnology Co.，LTD 15111215862 18229892877 3062105966@qq.com China 5569 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 13165688766 3504943249@qq.com China 3000 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Zhengzhou Lingzhiyue Technology Co., Ltd +86-0371-55074660 +86-13523716970 Lingzhiyue@aliyun.com China 3137 58
Supplier Advantage
Daicel Chiral Technologies (China)CO.,LTD 65
CR Corporation Limited 58
Suzhou Haiben Pharmaceutical Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Changsha Fuzhen Biotechnology Co.，LTD 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. 58
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 58
Zhengzhou Lingzhiyue Technology Co., Ltd 58

2306389-02-4 (L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-) Related Search:

Thalidomide-NH-PEG2-C2-NH2 hydrochloride Pomalidomide-PEG3-N3 Pentanediamide, N1-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-N5-[19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-4,7,10-trioxa-14-azanonadec-1-yl]- CAS:2722697-82-5 (S,R,S)-AHPC-Me-C6-NH2
-PEG4-amine

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L-Prolinamide, N-[8-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxooctyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- JYS005 VH032-C6-NH-Boc 2306389-02-4