Yangambin
- CAS No.
- 13060-14-5
- Chemical Name:
- Yangambin
- Synonyms
- C10894;YANGAMBIN;(+)-Yangabin;Yangambin, 10 mM in DMSO;Lrioresinol B dimethyl ether;Lirioresinol B dimethyl ether;(+)-O,O-Dimethyl lirioresinol B;yangambin/Lrioresinol B dimethyl ether;inhibit,Calcium Channel,Yangambin,Ca channels,Ca2+ channels,Inhibitor;(1β,5β)-2β,6β-Bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane
- CBNumber:
- CB31246402
- Molecular Formula:
- C24H30O8
- Molecular Weight:
- 446.49
- MDL Number:
- MFCD04307767
- MOL File:
- 13060-14-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 105-106 °C |
|---|---|
| Boiling point | 556.1±50.0 °C(Predicted) |
| Density | 1.183±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| color | White to off-white |
| InChIKey | HRLFUIXSXUASEX-RZTYQLBFSA-N |
| SMILES | O1C[C@]2([H])[C@@H](C3=CC(OC)=C(OC)C(OC)=C3)OC[C@]2([H])[C@H]1C1=CC(OC)=C(OC)C(OC)=C1 |
Yangambin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 44937 | Lirioresinol B dimethyl ether ≥98% | 13060-14-5 | 1mg | $85 | 2026-04-30 | Buy |
| Cayman Chemical | 44937 | Lirioresinol B dimethyl ether ≥98% | 13060-14-5 | 5mg | $361 | 2026-04-30 | Buy |
| Cayman Chemical | 44937 | Lirioresinol B dimethyl ether ≥98% | 13060-14-5 | 10mg | $595 | 2026-04-30 | Buy |
| Cayman Chemical | 44937 | Lirioresinol B dimethyl ether ≥98% | 13060-14-5 | 25mg | $956 | 2026-04-30 | Buy |
| Usbiological | 592523 | Lirioresinol B dimethylether | 13060-14-5 | 1mg | $674 | 2026-06-03 | Buy |
Yangambin Chemical Properties, Uses, Production
Uses
Yangambin is one of the active ingredients of Radix Stellerae Chamaejasmes, which is bitter in nature and taste, and is highly toxic. It has the effects of severe diarrhea, prevent decay, and swelling. It is clinically used for erysipelas, mammary carbuncle, swollen mumps (mumps), yellow water sores, and acne.
Definition
ChEBI: Yangambin is a lignan.
Biological Activity
Yangambin is a furofuran lignan that has been isolated from plants such as the Annonaceae family, including: R. pickeli, R. exalbida and R. mucosa and Magnolia biondii. Yangambin is a selective PAF receptor antagonist that inhibits Ca2+ influx by modulating Ca2+ channels, resulting in a decrease in [Ca2+] in vascular smooth muscle cells and subsequent peripheral vasodilation. Yangambin exhibits anti-allergic activity against β-hexosaminidase with IC50 of 33.8 μM and anti-inflammatory activity with IC50 of 37.4 μM.
Yangambin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Danding Pharmaceutical Technology Co., Ltd | 17701422019 17701422019 | 181646821@qq.com | China | 2421 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Winherb Medical Technology Co., Ltd. | 17301719108 13341702378 | winherb@126.com | China | 1245 | 58 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| Shanghai Haozhixiang Biotechnology Co., Ltd | 526763801 13301653310 | 526763801@qq.com | China | 7580 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Yihe Biological Technology Co., Ltd. | 021-68882955 17721395025 | 2423903095@qq.com | China | 4999 | 58 |
| Shanghai Uteam Biotechnology Co., Ltd. | 021-36031160 13311776681 | 3338195766@QQ.com | China | 5091 | 55 |
| Shanghai Biological Technology Development Co., Ltd. | 021-69955236-807 13918189704 | chinaruji@chinaruji.com | China | 5093 | 55 |
