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CPNQ

CPNQ Structure
CPNQ structure
CAS No.
115687-05-3
Chemical Name:
CPNQ
Synonyms
B2;CPNQ;SIRT2-IN-8;SIRT2 Inhibitor, B2;Linazolamide intermediate B impurity 2;5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline;(4-chlorophenyl)-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone;Methanone, (4-chlorophenyl)[4-(8-nitro-5-quinolinyl)-1-piperazinyl]-;Sirtuin,Parkinson’s diseases,Huntington’s diseases,Inhibitor,B2,inhibit,B-2
CBNumber:
CB9972382
Molecular Formula:
C20H17ClN4O3
Molecular Weight:
396.83
MDL Number:
MFCD02039810
MOL File:
115687-05-3.mol
Last updated:2026-02-02 18:10:39
Product description Number Pack Size Price
CPNQ ≥98% (HPLC), solid C3118 5mg $168
CPNQ ≥98% (HPLC), solid C3118 25mg $719
B2 B820015 1mg $200
B2 254701 10mg $403
CPNQ 95.00% API0008461 10MG $673.08
Request For Quotation

CPNQ Properties

Melting point 174-176°C
Boiling point 645.5±55.0 °C(Predicted)
Density 1.412±0.06 g/cm3(Predicted)
storage temp. Store at +4°C
solubility H2O: insoluble <2mg/mL
pka 2.30±0.29(Predicted)
form solid
color brown
Water Solubility H2O: insoluble <2mg/mL
DMSO: >5mg/mL
InChI 1S/C20H17ClN4O3/c21-15-5-3-14(4-6-15)20(26)24-12-10-23(11-13-24)17-7-8-18(25(27)28)19-16(17)2-1-9-22-19/h1-9H,10-13H2
InChIKey KLNPVNZJCWIQSK-UHFFFAOYSA-N
SMILES [O-][N+](=O)c1ccc(N2CCN(CC2)C(=O)c3ccc(Cl)cc3)c4cccnc14
UNSPSC Code 12352202
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319-H335
Precautionary statements  P301+P310+P330-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes  T
Risk Statements  25-36/37/38
Safety Statements  26-45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

CPNQ price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C3118 CPNQ ≥98% (HPLC), solid 115687-05-3 5mg $168 2025-07-31 Buy
Sigma-Aldrich C3118 CPNQ ≥98% (HPLC), solid 115687-05-3 25mg $719 2021-12-16 Buy
TRC B820015 B2 115687-05-3 1mg $200 2021-12-16 Buy
Usbiological 254701 B2 115687-05-3 10mg $403 2021-12-16 Buy
American Custom Chemicals Corporation API0008461 CPNQ 95.00% 115687-05-3 10MG $673.08 2021-12-16 Buy
Product number Packaging Price Buy
C3118 5mg $168 Buy
C3118 25mg $719 Buy
B820015 1mg $200 Buy
254701 10mg $403 Buy
API0008461 10MG $673.08 Buy

CPNQ Chemical Properties,Uses,Production

Uses

B2 is a cell permeable inhibitor of SIRT2 (sirtuin 2). Multidrug resistance protein 4 (MRP4) inhibitor in tumors such as neuroblastoma and colorectal cancer.

Definition

ChEBI: (4-chlorophenyl)-[4-(8-nitro-5-quinolinyl)-1-piperazinyl]methanone is a N-arylpiperazine.

Biological Activity

Promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease. Prevents huntingtin-mediated proteasome dysfunction and reduces α -synuclein-mediated toxicity.

IC 50

SIRT2

CPNQ Preparation Products And Raw materials

Raw materials

Preparation Products

CPNQ Suppliers

Global( 55)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32470 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15838 69
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 12952 65
Bide Pharmatech Ltd. 400-400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Zhengzhou Guancheng Laboratory equipment Sales 0371-88888888 272369594 2723695949@qq.com China 4981 50
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Supplier Advantage
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
BOC Sciences 65
Bide Pharmatech Ltd. 60
Zhengzhou Guancheng Laboratory equipment Sales 50
EMMX Biotechnology LLC 60
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60

View Lastest Price from CPNQ manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
B2 pictures 2026-02-02 B2
115687-05-3
 US $41.00-103.00 / mg 99.66% 10g TargetMol Chemicals Inc.
  • B2 pictures
  • B2
    115687-05-3
  • US $41.00-103.00 / mg
  • 99.66%
  • TargetMol Chemicals Inc.

CPNQ Spectrum

CPNQ(115687-05-3)1HNMR

115687-05-3(CPNQ)Related Search:

Oseltamivir phosphate 1-[4-(4-AMINO-PHENYL)-PIPERAZIN-1-YL]-ETHANONE CPNQ 4-(4-BENZYLPIPERAZINO)ANILINE 1-BENZYL-4-(4-NITROPHENYL)PIPERAZINE
(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE 1-Acetyl-4-(4-nitrophenyl)piperazine 1-(4-Nitrophenyl)piperazine

1of2

5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline B2 Linazolamide intermediate B impurity 2 (4-chlorophenyl)-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone SIRT2 Inhibitor, B2 Methanone, (4-chlorophenyl)[4-(8-nitro-5-quinolinyl)-1-piperazinyl]- Sirtuin,Parkinson’s diseases,Huntington’s diseases,Inhibitor,B2,inhibit,B-2 SIRT2-IN-8 CPNQ 115687-05-3