HEXAMETHONIUM CHLORIDE
- CAS No.
- 60-25-3
- Chemical Name:
- HEXAMETHONIUM CHLORIDE
- Synonyms
- HEXAMETHONIUM DICHLORIDE;depressin;hexonchloride;hiohexchloride;hexonechloride;esomidchloride;methiumchloride;chloor-hexaviet;bistriumchloride;hestriumchloride
- CBNumber:
- CB3125713
- Molecular Formula:
- C12H30Cl2N2
- Molecular Weight:
- 273.29
- MDL Number:
- MFCD00031563
- MOL File:
- 60-25-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Hexamethonium chloride solid (hygroscopic) | H2138 | 5g | $37.4 |
| Hexamethonium chloride solid (hygroscopic) | H2138 | 25g | $154 |
| Hexamethonium Chloride Dihydrate >99.0%(T) | H0090 | 25g | $114 |
| Hexamethonium Chloride Dihydrate >99.0%(T) | H0090 | 100g | $287 |
| Hexamethonium chloride ≥98% | CS-0013618 | 500mg | $27 |
| Melting point | 292°C(dec.)(lit.) |
|---|---|
| Boiling point | 423.36°C (rough estimate) |
| Density | 1.0558 (rough estimate) |
| refractive index | 1.6400 (estimate) |
| solubility | H2O: soluble |
| form | solid (hygroscopic) |
| color | white |
| Water Solubility | almost transparency |
| BRN | 3714806 |
| InChI | 1S/C12H30N2.2ClH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2 |
| InChIKey | PYIHTIJNCRKDBV-UHFFFAOYSA-L |
| SMILES | [Cl-].[Cl-].C[N+](C)(C)CCCCCC[N+](C)(C)C |
| CAS DataBase Reference | 60-25-3 |
| FDA UNII | TIV4Q933FU |
| EPA Substance Registry System | 1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, dichloride (60-25-3) |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| RTECS | BQ8650000 |
| TSCA | TSCA listed |
| HS Code | 2923.90.0100 |
| Storage Class | 11 - Combustible Solids |
HEXAMETHONIUM CHLORIDE price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H2138 | Hexamethonium chloride solid (hygroscopic) | 60-25-3 | 5g | $37.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | H2138 | Hexamethonium chloride solid (hygroscopic) | 60-25-3 | 25g | $154 | 2026-04-30 | Buy |
| TCI Chemical | H0090 | Hexamethonium Chloride Dihydrate >99.0%(T) | 60-25-3 | 25g | $114 | 2025-07-31 | Buy |
| TCI Chemical | H0090 | Hexamethonium Chloride Dihydrate >99.0%(T) | 60-25-3 | 100g | $287 | 2025-07-31 | Buy |
| ChemScene | CS-0013618 | Hexamethonium chloride ≥98% | 60-25-3 | 500mg | $27 | 2026-06-04 | Buy |
HEXAMETHONIUM CHLORIDE Chemical Properties,Uses,Production
Chemical Properties
White, crystalline, hygroscopic powder; faint odor. Very soluble in water; soluble in alcohol, methanol, and n-propanol; insoluble in chloroform and ether. Available commercially as unhydrated form or as dihydrate.
Uses
Hexamethonium Chloride is a ganglionic nicotinic receptor blocker.
Uses
Hexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons.
Uses
Medicine (antihypertensive).
General Description
Nicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction.
Biochem/physiol Actions
Hexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia, crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognitive impairment. nAChR antagonist is used to study the effect of loss of receptor function. Hexamethonium has a peripheral action over blocking the nAChR.
HEXAMETHONIUM CHLORIDE Preparation Products And Raw materials
HEXAMETHONIUM CHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Chemsigma International Co., Ltd. | +86-2558742998 +86-19951791336 | info@chemsigma.com | China | 1824 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 | info@fortunachem.com | China | 5998 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| CD Chemical Group Limited | +86-13651442114 | info@codchem.com | China | 17253 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9322 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49859 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
View Lastest Price from HEXAMETHONIUM CHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-26 | Hexamethonium chloride
60-25-3
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-05-11 | Hexamethonium chloride
60-25-3
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-04-04 | HEXAMETHONIUM CHLORIDE
60-25-3
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- Hexamethonium chloride
60-25-3
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Hexamethonium chloride
60-25-3
- $1520.00-2500.00
- TargetMol Chemicals Inc.
-
- HEXAMETHONIUM CHLORIDE
60-25-3
- 98%
- Henan Aochuang Chemical Co.,Ltd.
