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4-(Pyridin-3-yloxy)-phenylamine

CAS No.
80650-45-9
Chemical Name:
4-(Pyridin-3-yloxy)-phenylamine
Synonyms
4-(pyridin-3-yloxy)aniline;Albb-005633;TIMTEC-BB SBB010739;IFLAB-BB F2108-0080;4-(Pyridin-3-yloxy);4-(3-pyridyloxy)aniline;ASINEX-REAG BAS 10148925;4-(3-Pyridinyloxy)aniline;4-(3-Pyridinyloxy)phenylamine;[4-(3-pyridyloxy)phenyl]amine
CBNumber:
CB3126664
Molecular Formula:
C11H10N2O
Molecular Weight:
186.21
MDL Number:
MFCD07186369
MOL File:
80650-45-9.mol
Last updated:2026-09-12 18:51:33

4-(Pyridin-3-yloxy)-phenylamine Properties

Melting point 98-105 °C(Solv: ethanol (64-17-5); water (7732-18-5))
Boiling point 346.2±22.0 °C(Predicted)
Density 1+-.0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form solid
pka 4.57±0.10(Predicted)
Appearance Off-white to yellow Solid
InChI 1S/C11H10N2O/c12-9-3-5-10(6-4-9)14-11-2-1-7-13-8-11/h1-8H,12H2
InChIKey ZSLIXJKSPVCNHZ-UHFFFAOYSA-N
SMILES NC1=CC=C(C=C1)OC2=CC=CN=C2
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280
Hazard Codes  Xi
Risk Statements  43
Safety Statements  36/37
HazardClass  IRRITANT
HS Code  2933399990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Skin Sens. 1

4-(Pyridin-3-yloxy)-phenylamine price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CBR00249 4-(Pyridin-3-yloxy)aniline Aldrich 80650-45-9 1g $93.2 2026-04-30 Buy
Apolloscientific OR905968 4-(Pyridin-3-yloxy)-phenylamine 95% 80650-45-9 100mg $29 2026-06-04 Buy
Apolloscientific OR905968 4-(Pyridin-3-yloxy)-phenylamine 95% 80650-45-9 250mg $43 2026-06-04 Buy
Apolloscientific OR905968 4-(Pyridin-3-yloxy)-phenylamine 95% 80650-45-9 1g $60 2026-06-04 Buy
Apolloscientific OR905968 4-(Pyridin-3-yloxy)-phenylamine 95% 80650-45-9 5g $179 2026-06-04 Buy
Product number Packaging Price Buy
CBR00249 1g $93.2 Buy
OR905968 100mg $29 Buy
OR905968 250mg $43 Buy
OR905968 1g $60 Buy
OR905968 5g $179 Buy

4-(Pyridin-3-yloxy)-phenylamine Chemical Properties, Uses, Production

Synthesis

3-(4-nitrophenoxy)pyridine

28232-53-3

4-(PYRIDIN-3-YLOXY)-PHENYLAMINE

80650-45-9

Synthesis of compound 34-2 (0476): To a solution of 34-1 (2.0 g, 9.259 mmol) in methanol (20 mL) was added 10% palladium/carbon (0.2 g) purged with nitrogen. Hydrogen was subsequently passed to displace the nitrogen. The reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to dryness to afford 34-2 (1.7 g, 99% yield) as a brown solid.

References

[1] Patent: US9138427, 2015, B2. Location in patent: Page/Page column 309
[2] Patent: WO2014/176258, 2014, A1. Location in patent: Page/Page column 30
[3] Patent: WO2004/85399, 2004, A1. Location in patent: Page 168
[4] Patent: WO2005/4863, 2005, A1. Location in patent: Page/Page column 128
[5] Patent: WO2004/19941, 2004, A1. Location in patent: Page/Page column 154

4-(Pyridin-3-yloxy)-phenylamine Preparation Products And Raw materials

4-(Pyridin-3-yloxy)-phenylamine Suppliers

Global Suppliers ( 59)
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Hangzhou Molcore Biopharmatech Co.,Ltd 400-711-5280 86-571-81025280 sales@molcore.com China 9957 58

4-(Pyridin-3-yloxy)-phenylamine Spectrum

ASINEX-REAG BAS 10148925 IFLAB-BB F2108-0080 TIMTEC-BB SBB010739 4-(3-Pyridinyloxy)phenylamine Albb-005633 4-(pyridin-3-yloxy)aniline(SALTDATA: FREE) [4-(3-pyridyloxy)phenyl]amine 4-(3-pyridyloxy)aniline Benzenamine,4-(3-pyridinyloxy)- 4-(Pyridin-3-yloxy) 4-(pyridin-3-yloxy)aniline 4-(Pyridin-3-yloxy)-phenylamine 4-(3-Pyridinyloxy)aniline 80650-45-9