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ChemicalBook >> CAS DataBase List >>Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy-

Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy-

Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Structure
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- structure
CAS No.
2446664-72-6
Chemical Name:
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy-
Synonyms
FGFR3-IN-5;Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy-
CBNumber:
CB312905341
Molecular Formula:
C24H24FN7O3
Molecular Weight:
477.49
MDL Number:
MOL File:
2446664-72-6.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
Request For Quotation

Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Properties

Density 1.43±0.1 g/cm3(Predicted)
pka 0.45±0.19(Predicted)
form Solid
color White to off-white

Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0640675 FGFR3-IN-5 99.16% 2446664-72-6 1mg $401 2026-06-04 Buy
ChemScene CS-0640675 FGFR3-IN-5 99.16% 2446664-72-6 5mg $867 2026-06-04 Buy
ChemScene CS-0640675 FGFR3-IN-5 99.16% 2446664-72-6 10mg $1300 2026-06-04 Buy
ChemScene CS-0640675 FGFR3-IN-5 99.16% 2446664-72-6 25mg $2340 2026-06-04 Buy
ChemScene CS-0640675 FGFR3-IN-5 99.16% 2446664-72-6 50mg $3510 2026-06-04 Buy
Product number Packaging Price Buy
CS-0640675 1mg $401 Buy
CS-0640675 5mg $867 Buy
CS-0640675 10mg $1300 Buy
CS-0640675 25mg $2340 Buy
CS-0640675 50mg $3510 Buy

Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Chemical Properties,Uses,Production

Uses

FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer[1].

IC 50

FGFR3: 3 nM (IC50); FGFR2: 44 nM (IC50); FGFR1: 289 nM (IC50)

References

[1] James FB, et, al. Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of fgfr tyrosine kinases. WO2020131627.

Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Preparation Products And Raw materials

Raw materials

Preparation Products

Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Afflon Pharmaceutical (Sichuan) Co., Ltd. 17336178085 1684779048@qq.com China 2263 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Afflon Pharmaceutical (Sichuan) Co., Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Lastest Price from Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FGFR3-IN-5 pictures 2026-07-27 FGFR3-IN-5
2446664-72-6
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • FGFR3-IN-5 pictures
  • FGFR3-IN-5
    2446664-72-6
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.

2446664-72-6(Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy-)Related Search:

FGFR-1 alpha (iiic) protein, human (biotinylated, HEK293, His-AVI) FGFR-2 BETA (IIIB) Protein, HUMAN (HEK293, HIS) FGFR-3 beta (iiic) protein, human (biotinylated, HEK293, His-AVI) FGFR-4 Protein, HUMAN (HEK293, HIS) Futibatinib
Formononetin

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Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-[1-[1-[[3-fluoro-1-(1-oxo-2-propen-1-yl)-3-azetidinyl]carbonyl]-4-piperidinyl]-1H-pyrazol-4-yl]-4-methoxy- FGFR3-IN-5 2446664-72-6