1-(2-Chloroethoxy)-4-nitrobenzene
- CAS No.
- 3383-72-0
- Chemical Name:
- 1-(2-Chloroethoxy)-4-nitrobenzene
- Synonyms
- β-chloro-4-nitrophenethole;BETA-CHLORO-4-NITROPHENETHOLE;4-(2-Chloroethoxy)nitrobenzene;2-(4-NITROPHENOXY)ETHYL CHLORIDE;4-Nitro-1-(2-chloroethoxy)benzene;1-(2-CHLOROETHOXY)-4-NITROBENZENE;2-CHLOROETHYL-4-NITROPHENYL ETHER;Benzene, 1-(2-chloroethoxy)-4-nitro-;1-(2-Chloroethoxy)-4-nitrobenzene,97%;1-(2-CHLOROETHOXY)4-NITROBENZENE, 98+%
- CBNumber:
- CB3136632
- Molecular Formula:
- C8H8ClNO3
- Molecular Weight:
- 201.61
- MDL Number:
- MFCD00674505
- MOL File:
- 3383-72-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-(2-Chloroethoxy)-4-nitrobenzene >98.0%(GC) | C3523 | 1g | $80 |
| 1-(2-Chloroethoxy)-4-nitrobenzene >98.0%(GC) | C3523 | 5g | $240 |
| 1-(2-Chloroethoxy)-4-nitrobenzene Asreported | 269193 | 1g | $396 |
| 1-(2-Chloroethoxy)-4-nitrobenzene Asreported | 269193 | 2g | $623 |
| 1-(2-Chloroethoxy)-4-nitrobenzene Asreported | 269193 | 5g | $941 |
| More product size | |||
| Melting point | 67-68 °C |
|---|---|
| Boiling point | 204-206 °C(Press: 25 Torr) |
| Density | 1.316±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| color | White to Light yellow |
| InChI | InChI=1S/C8H8ClNO3/c9-5-6-13-8-3-1-7(2-4-8)10(11)12/h1-4H,5-6H2 |
| InChIKey | OBCFOPGCTNULTG-UHFFFAOYSA-N |
| SMILES | C1(OCCCl)=CC=C([N+]([O-])=O)C=C1 |
| CAS DataBase Reference | 3383-72-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H335-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 9-21 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2909309090 | |||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
1-(2-Chloroethoxy)-4-nitrobenzene price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C3523 | 1-(2-Chloroethoxy)-4-nitrobenzene >98.0%(GC) | 3383-72-0 | 1g | $80 | 2026-04-30 | Buy |
| TCI Chemical | C3523 | 1-(2-Chloroethoxy)-4-nitrobenzene >98.0%(GC) | 3383-72-0 | 5g | $240 | 2026-04-30 | Buy |
| Usbiological | 269193 | 1-(2-Chloroethoxy)-4-nitrobenzene Asreported | 3383-72-0 | 1g | $396 | 2026-06-03 | Buy |
| Usbiological | 269193 | 1-(2-Chloroethoxy)-4-nitrobenzene Asreported | 3383-72-0 | 2g | $623 | 2026-06-03 | Buy |
| Usbiological | 269193 | 1-(2-Chloroethoxy)-4-nitrobenzene Asreported | 3383-72-0 | 5g | $941 | 2026-06-03 | Buy |
1-(2-Chloroethoxy)-4-nitrobenzene Chemical Properties,Uses,Production
Synthesis
100-02-7
107-04-0
3383-72-0
1-(2-Chloroethoxy)-4-nitrobenzene was synthesized as follows: cesium carbonate (28.7 mmol) was added to a solution of 4-nitrophenol (28.7 mmol) in anhydrous ethanol (15 mL), followed by 1-bromo-2-chloroethane (86.2 mmol). The reaction mixture was heated to reflux at 80 °C for 8 hours. Upon completion of the reaction, the mixture was cooled, the reaction was quenched with water and extracted with ethyl acetate (EtOAc). The organic layers were combined, washed sequentially with water and brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to give an orange residue. Grinding of the residue with ethanol (EtOH) gave 1-(2-chloroethoxy)-4-nitrobenzene in 66% yield. Mass spectrum (MS) (m/z): (M+1)+ 202.2.
References
[1] Patent: WO2007/38669, 2007, A2. Location in patent: Page/Page column 170
[2] Journal of Medicinal Chemistry, 2006, vol. 49, # 16, p. 4981 - 4991
[3] Patent: WO2005/68452, 2005, A1. Location in patent: Page/Page column 41
[4] Journal of Medicinal Chemistry, 2008, vol. 51, # 6, p. 1637 - 1648
[5] Patent: WO2004/5282, 2004, A1. Location in patent: Page 39
1-(2-Chloroethoxy)-4-nitrobenzene Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 340 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3989 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9631 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
View Lastest Price from 1-(2-Chloroethoxy)-4-nitrobenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-24 | 1-(2-Chloroethoxy)-4-nitrobenzene
3383-72-0
|
1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | ||
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2019-09-02 | 1-(2-Chloroethoxy)-4-nitrobenzene
3383-72-0
|
$7.00 | 1KG | 99% | Career Henan Chemical Co |
-

- 1-(2-Chloroethoxy)-4-nitrobenzene
3383-72-0
- $0.10
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-

- 1-(2-Chloroethoxy)-4-nitrobenzene
3383-72-0
- $7.00
- 99%
- Career Henan Chemical Co





