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BDM88855

CAS No.
2892824-25-6
Chemical Name:
BDM88855
Synonyms
BDM88855;Quinoline, 3-chloro-2-(1-piperazinyl)-
CBNumber:
CB313732023
Molecular Formula:
C13H14ClN3
Molecular Weight:
247.72
MDL Number:
MOL File:
2892824-25-6.mol
MSDS File:
SDS
Last updated:2025-05-19 13:47:27

BDM88855 Properties

Boiling point 414.131±40.00 °C(Press: 760.00 Torr)(predicted)
Density 1.257±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 8.309±0.10(predicted)

BDM88855 Chemical Properties, Uses, Production

Uses

BDM88855 is an allosteric inhibitor for the homolog AcrB protein. BDM88855 can boost the antibacterial effect of a panel of antibiotics (eg: Oxacillin (HY-B0925A), Linezolid (HY-10394), Novobiocin (HY-B0425), etc.) on wild-type E. coli[1][2].

References

[1] Plé C, et al. Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps. Nat Commun. 2022 Jan 10;13(1):115. DOI:10.1038/s41467-021-27726-2
[2] Bera A, et al. Exploring transmembrane allostery in the MexB: DB08385 variant as a promising inhibitor-like candidate against Pseudomonas aeruginosa antibiotic resistance: a computational study. Phys DOI:10.1039/d4cp01620c

BDM88855 Preparation Products And Raw materials

Raw materials

Preparation Products

BDM88855 Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
BDM88855 Quinoline, 3-chloro-2-(1-piperazinyl)- 2892824-25-6