BDM88855
- CAS No.
- 2892824-25-6
- Chemical Name:
- BDM88855
- Synonyms
- BDM88855;Quinoline, 3-chloro-2-(1-piperazinyl)-
- CBNumber:
- CB313732023
- Molecular Formula:
- C13H14ClN3
- Molecular Weight:
- 247.72
- MDL Number:
- MOL File:
- 2892824-25-6.mol
- MSDS File:
- SDS
BDM88855 Chemical Properties, Uses, Production
Uses
BDM88855 is an allosteric inhibitor for the homolog AcrB protein. BDM88855 can boost the antibacterial effect of a panel of antibiotics (eg: Oxacillin (HY-B0925A), Linezolid (HY-10394), Novobiocin (HY-B0425), etc.) on wild-type E. coli[1][2].
References
[1] Plé C, et al. Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps. Nat Commun. 2022 Jan 10;13(1):115. DOI:10.1038/s41467-021-27726-2
[2] Bera A, et al. Exploring transmembrane allostery in the MexB: DB08385 variant as a promising inhibitor-like candidate against Pseudomonas aeruginosa antibiotic resistance: a computational study. Phys DOI:10.1039/d4cp01620c
BDM88855 Preparation Products And Raw materials
Raw materials
Preparation Products
BDM88855 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |




