ficellomycin
- CAS No.
- 59458-27-4
- Chemical Name:
- ficellomycin
- Synonyms
- U 47929;ficellomycin;Antibiotic U 47929;Glycine, valyl-2-[4-[(aminoiminomethyl)amino]-1-azabicyclo[3.1.0]hex-2-yl]-
- CBNumber:
- CB31385037
- Molecular Formula:
- C13H24N6O3
- Molecular Weight:
- 312.37
- MDL Number:
- MFCD01939598
- MOL File:
- 59458-27-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| EWG's Food Scores | 1 |
|---|
ficellomycin Chemical Properties, Uses, Production
Uses
Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases[1].
Definition
ChEBI: Ficellomycin is a dipeptide antibiotic containing an azabicyclohexane ring system that exhibits potent in vitro activity against Penicillium oxalicum and Staphylococcus aureus. It inhibits semi-conservative DNA replication by causing accumulation of 34S DNA species. It has a role as an antibacterial agent, a DNA synthesis inhibitor and a bacterial metabolite. It is a dipeptide, a member of pyrrolidines, a member of aziridines and an alkaloid. It contains a guanidino group and a L-valine.
References
[1] He X, et al. Ficellomycin: an aziridine alkaloid antibiotic with potential therapeutic capacity. Appl Microbiol Biotechnol. 2018 May;102(10):4345-4354. DOI:10.1007/s00253-018-8934-4
ficellomycin Preparation Products And Raw materials
Raw materials
Preparation Products
ficellomycin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Zhejiang Huida Biotech Co., LTD | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
