ChemicalBook >> CAS DataBase List >>NG-MONOMETHYL-L-ARGININE ACETATE

NG-MONOMETHYL-L-ARGININE ACETATE

CAS No.
53308-83-1
Chemical Name:
NG-MONOMETHYL-L-ARGININE ACETATE
Synonyms
L-NMMA;NMMA;904;L-NMMA ACETATE;CP47;CP 47;CP-47;ANO 1020;NG<;NG-ME-L-ARG, ACOH
CBNumber:
CB3138560
Molecular Formula:
C7H16N4O2.C2H4O2
Molecular Weight:
248.28
MDL Number:
MFCD00069311
MOL File:
53308-83-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

NG-MONOMETHYL-L-ARGININE ACETATE Properties

Melting point 180-190 °C
alpha D22 +9.5° (c = 0.10 in water)
Boiling point 391.35°C (rough estimate)
Density 1.2162 (rough estimate)
refractive index 1.6300 (estimate)
storage temp. 2-8°C
solubility H2O: 1 mg/mL, clear, colorless
form Powder
color White to Off-white
Water Solubility Soluble in water (50 mM)
BRN 6674255
Stability Store at - 5°C; Desiccate Recommended
InChI 1S/C7H16N4O2.C2H4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13;1-2(3)4/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11);1H3,(H,3,4)/t5-;/m0./s1
InChIKey IKPNWIGTWUZCKM-JEDNCBNOSA-N
SMILES CC(O)=O.CNC(=N)NCCC[C@H](N)C(O)=O
FDA UNII 2FL3530AF2
UNSPSC Code 12352209
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
HS Code  29252900
Storage Class 11 - Combustible Solids

NG-MONOMETHYL-L-ARGININE ACETATE price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M1365 Nω-Monomethyl-L-arginine Acetate >98.0%(T) 53308-83-1 100mg $199 2024-03-01 Buy
Cayman Chemical 10005031 L-NMMA (acetate) ≥99% 53308-83-1 5mg $19 2026-04-30 Buy
Cayman Chemical 10005031 L-NMMA (acetate) ≥99% 53308-83-1 25mg $74 2026-04-30 Buy
Cayman Chemical 10005031 L-NMMA (acetate) ≥99% 53308-83-1 50mg $130 2026-04-30 Buy
Cayman Chemical 10005031 L-NMMA (acetate) ≥99% 53308-83-1 100mg $228 2026-04-30 Buy
Product number Packaging Price Buy
M1365 100mg $199 Buy
10005031 5mg $19 Buy
10005031 25mg $74 Buy
10005031 50mg $130 Buy
10005031 100mg $228 Buy

NG-MONOMETHYL-L-ARGININE ACETATE Chemical Properties,Uses,Production

Description

L-NMMA is the archetypal competitive NOS inhibitor to which other inhibitors are often compared. It is a relatively non-selective inhibitor of all NOS isoforms. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 μM, respectively.

Chemical Properties

White Crystalline Powder

Uses

A potent inhibitor of NO synthase of adrenal glands, brain, and vascular endothelial cells

Uses

Reagent to inhibit nitric oxide production in biological systems.

Uses

Nitric oxide synthase inhibitor

Biological Activity

Competitive, irreversible inhibitor of all three NOS isoforms.

Biochem/physiol Actions

NG-Methyl-L-arginine is an inhibitor of nitric oxide synthase in neurons, endothelial cells, and macrophages. It inhibits endothelium-derived relaxing factor and promotes contraction in pulmonary artery and vein. It stereo selectively inhibits the generation of nitric oxide (NO) from arginine. It promotes epinephrine and glucose levels, contributing to hyperglycemia in central nervous system.

storage

Room temperature

References

[1] O W GRIFFITH  R G K. Nitric oxide synthase inhibitors: amino acids.[J]. Methods in enzymology, 1996, 268: 375-392. DOI: 10.1016/s0076-6879(96)68040-9
[2] C FREY. L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases.[J]. The Journal of Biological Chemistry, 1994, 269 42: 26083-26091.
[3] GARVEY E.P. Purification and Characterization of the Constitutive Nitric-Oxide Synthase from Human Placenta[J]. Archives of biochemistry and biophysics, 1994, 311 2: Pages 235-241. DOI: 10.1006/abbi.1994.1232

NG-MONOMETHYL-L-ARGININE ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

NG-MONOMETHYL-L-ARGININE ACETATE Suppliers

Global( 174)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Ascent Scientific 4401179829988 customerservice@ascentscientific.co.uk United Kingdom 279 60
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shanghai Feibo Chemical Technology Co., Ltd 021-58955608,2250286 15921236618 blinkzeng@gmail.com China 522 62
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75

View Lastest Price from NG-MONOMETHYL-L-ARGININE ACETATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-NMMA acetate pictures 2026-07-27 L-NMMA acetate
53308-83-1
$40.00-98.00 99.80% 10g TargetMol Chemicals Inc.
NoMega-MonoMethyl-L-arginine Acetate pictures 2025-06-25 NoMega-MonoMethyl-L-arginine Acetate
53308-83-1
$1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd

NG-MONOMETHYL-L-ARGININE ACETATE Spectrum

NG-Methyl-L-arginine acetate salt >=95% (HPLC) Ngamma-methyl-L-arginine acetate L-NMMA, NG-Monomethyl-L-arginine acetate salt, Nω-Methyl-L-arginine acetate salt, N5-(Methylamidino)-L-ornithine acetate salt N-Monomethyl-L-arginine Nα-Methyl-L-arginine NG-Monomethyl-L-arginine monoacetate,99% NG-Monomethyl-L-arginine acetate salt L-NG-Monomethylarginine, Acetate Salt (L-NMMA) NG-Monomethyl-L-arginine Acetate NG-Monomethyl-L-arginine, Monoacetate Salt - CAS 53308-83-1 - Calbiochem H-L-Arg(Me)-OH acetate N5-[METHYLAMIDINO]-L-ORNITHINE ACETATE SALT N5-[IMINO(METHYLAMINO)METHYL]-L-ORNITHINE, MONOACETATE N-GAMMA-MONOMETHYL-L-ARGININE ACETATE NG-ME-L-ARG, ACOH NG-MONOMETHYL-L-ARGININE MONACETATE NG-MONOMETHYL-L-ARGININE MONOACETATE NG-MONOMETHYL-L-ARGININE, MONOACETATE SALT NG-MONOMETHYL-L-ARGININE ACETATE NG-METHYL-L-ARGININE ACETATE NG-METHYL-L-ARGININE ACETATE SALT NG-METHYL-L-ARGININE MONOACETATE SALT NMMA ACETATE SALT N-OMEGA-ME-L-ARG, MONOACETATE SALT NOMEGA-MONOMETHYL-L-ARGININE ACETATE N-OMEGA-METHYL-L-ARGININE ACETATE nω-methyl-l-arginine acetate salt N-Monomethyl-L-arginine monoacetate. NW-METHYL-L-ARGININE L-NG-MONOMETHYLARGININE, ACETATE SALT L-NMMA MONOACETATE L-NMMA, MONOACETATE SALT L-NMMA, ACETATE SALT H-ARG(ME)-OH ACOH ANO 1020 N5-[Imino(methylamino)methyl]-L-ornithine Acetate Tilarginine Acetate Nω-Monomethyl-L-arginineAcetate> Methylarginine acetate Nω-Methyl-L-arginine Acetate N-omega-Monomethyl-L-arginine monoacetate, 99% NG-MONOMETHYL-L-ARGININE ACETATE USP/EP/BP (2S)-5-{[(E)-amino(methyliminio)methyl]amino}-2-ammoniopentanoate CP 47 CP47 CP-47 Arginine impurity 25 (acetate) NG< NG-Monomethyl-L-arginine, monoacetate salt (L-NMMA), NOS inhibitor NG-Methyl-L-arginine acetate salt NG-Monomethyl-L-arginine, Monoacetate Salt 904 L-NMMA L-NMMA ACETATE NMMA N-omega-Monomethyl-L-arginine monoacetate 53308-83-1 C7H18N4O2