ChemicalBook >> CAS DataBase List >>5,7-dichlorothiazolo[5,4-d]pyrimidine

5,7-dichlorothiazolo[5,4-d]pyrimidine

5,7-dichlorothiazolo[5,4-d]pyrimidine structure

CAS No.: 13479-88-4

Chemical Name:: 5,7-dichlorothiazolo[5,4-d]pyrimidine

Synonyms: 5,7-dichlorothiazolo[5,4-d]pyrimidine;Thiazolo[5,4-d]pyrimidine, 5,7-dichloro-;5,7-dichloro-[1,3]thiazolo[5,4-d]pyriMidine

CBNumber:: CB31483436

Molecular Formula:: C5HCl2N3S

Molecular Weight:: 206.05

MDL Number:: MFCD09702027

MOL File:: 13479-88-4.mol

MSDS File:: SDS

Last updated:2026-05-28 00:57:59

Request For Quotation

5,7-dichlorothiazolo[5,4-d]pyrimidine Properties

Melting point	148.5-149.5 °C
Boiling point	281.2±22.0 °C(Predicted)
Density	1.767±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMF: 2 mg/ml,DMSO: 1 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
form	A solid
pka	-2.68±0.50(Predicted)
color	Light yellow to brown
InChI	InChI=1S/C5HCl2N3S/c6-3-2-4(11-1-8-2)10-5(7)9-3/h1H
InChIKey	XYBGDWLYHQAUQM-UHFFFAOYSA-N
SMILES	C1(Cl)=NC(Cl)=C2N=CSC2=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H332-H335

Precautionary statements

P261-P280-P305+P351+P338

NFPA 704

	0
2		0

5,7-dichlorothiazolo[5,4-d]pyrimidine price More Price(59)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	36489	5,7-Dichlorothiazolo[5,4-d]pyrimidine ≥95%	13479-88-4	50mg	$70	2026-04-30	Buy
Cayman Chemical	36489	5,7-Dichlorothiazolo[5,4-d]pyrimidine ≥95%	13479-88-4	100mg	$124	2026-04-30	Buy
Cayman Chemical	36489	5,7-Dichlorothiazolo[5,4-d]pyrimidine ≥95%	13479-88-4	250mg	$240	2026-04-30	Buy
Cayman Chemical	36489	5,7-Dichlorothiazolo[5,4-d]pyrimidine ≥95%	13479-88-4	500mg	$443	2026-04-30	Buy
ChemScene	CS-W018716	5,7-Dichlorothiazolo[5,4-d]pyrimidine ≥95%	13479-88-4	250mg	$24	2026-06-04	Buy

Product number	Packaging	Price	Buy
36489	50mg	$70	Buy
36489	100mg	$124	Buy
36489	250mg	$240	Buy
36489	500mg	$443	Buy
CS-W018716	250mg	$24	Buy

5,7-dichlorothiazolo[5,4-d]pyrimidine Chemical Properties, Uses, Production

Uses

5,7-Dichlorothiazolo[5,4-d]pyrimidine was used in studies to prepare Kinase inhibitors.

Synthesis

thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione

5082-82-6

13479-88-4

The general procedure for the synthesis of 5,7-dichlorothiazolo[5,4-d]pyrimidine using thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione as starting material was as follows: a 10 mL round bottom flask was charged with intermediate 45.2 (100 mg, 0.59 mmol, 1.00 equiv.), N,N-diisopropylethylamine (DIEA, 0.5 mL) and phosphorus oxychloride (POCl3, 2 mL). The reaction mixture was stirred at 100 °C for 12 hours. After completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The crude product was purified by fast column chromatography to afford intermediate 45.3 (100 mg, 82% yield) as a yellow oil.

References

[1] Heterocycles, 2012, vol. 85, # 7, p. 1721 - 1726
[2] Patent: WO2015/48281, 2015, A1. Location in patent: Paragraph 00472; 00475
[3] Patent: WO2014/15291, 2014, A1. Location in patent: Page/Page column 168; 169
[4] Journal of the American Chemical Society, 1951, vol. 73, p. 3862

5,7-dichlorothiazolo[5,4-d]pyrimidine Preparation Products And Raw materials

Raw materials

thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione

Preparation Products

5,7-dichlorothiazolo[5,4-d]pyrimidine Suppliers

Global Suppliers ( 125)

Supplier	Tel	Email	Country	ProdList	Advantage
Nantong MYBio-pharm. Co., Ltd.	0513-85921823 18662920231	sales@ntminyanmedical.com	China	4563	58
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
China Langchem Inc.	0086-21-58956006		China	7798	57
Wuhan ariel chemical Co., LTD.	18986259541 18986259541	sales@3stc.com	China	3828	58
Chiba Pharmaceutical Science and technology Co, Ltd.	0531-81313138 13066006660	chibapharm@foxmail.com	China	3996	55
Shanghai Topbiochem Technology Co., Ltd	021-58170097	info@topbiochem.com	China	9509	58

Supplier	Advantage
Nantong MYBio-pharm. Co., Ltd.	58
Beijing Ouhe Technology Co., Ltd	60
Pure Chemistry Scientific Inc.	62
Accela ChemBio Co.,Ltd.	64
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
China Langchem Inc.	57
Wuhan ariel chemical Co., LTD.	58
Chiba Pharmaceutical Science and technology Co, Ltd.	55
Shanghai Topbiochem Technology Co., Ltd	58

View Latest Price from 5,7-dichlorothiazolo[5,4-d]pyrimidine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-05-17	5,7-dichlorothiazolo[5,4-d]pyriMidine 13479-88-4	$1.00	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd
	2019-07-06	5,7-dichlorothiazolo[5,4-d]pyrimidine 13479-88-4	$1.00	1kg	97%-99%		Career Henan Chemical Co

5,7-dichlorothiazolo[5,4-d]pyriMidine
13479-88-4
$1.00
99%
Shaanxi Dideu Medichem Co. Ltd

5,7-dichlorothiazolo[5,4-d]pyrimidine
13479-88-4
$1.00
97%-99%
Career Henan Chemical Co

5,7-dichlorothiazolo[5,4-d]pyrimidine Spectrum

5,7-dichlorothiazolo[5,4-d]pyrimidine(13479-88-4)¹HNMR

13479-88-4 (5,7-dichlorothiazolo[5,4-d]pyrimidine) Related Search:

5,7-dichlorothiazolo[5,4-d]pyrimidine 7-chlorothiazolo[5,4-d]pyrimidine 7-Chloro-5-methylthiazolo[5,4-d]pyrimidine 3,5-dichloro-8-methyl-9-thia-2,4,7-triazabicyclo[4.3.0]nona-2,4,7,10-tetraene Thiazolo[5,4-d]pyrimidine, 2-bromo-5,7-dichloro-

2,7-Dichlorothiazolo[5,4-d]pyrimidine

1of2

5,7-dichloro-[1,3]thiazolo[5,4-d]pyriMidine 5,7-dichlorothiazolo[5,4-d]pyrimidine Thiazolo[5,4-d]pyrimidine, 5,7-dichloro- 13479-88-4 Heterocycle-Pyrimidine series