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ChemicalBook >> CAS DataBase List >>5,7-dichlorothiazolo[5,4-d]pyrimidine

5,7-dichlorothiazolo[5,4-d]pyrimidine

5,7-dichlorothiazolo[5,4-d]pyrimidine Structure
5,7-dichlorothiazolo[5,4-d]pyrimidine structure
CAS No.
13479-88-4
Chemical Name:
5,7-dichlorothiazolo[5,4-d]pyrimidine
Synonyms
5,7-dichlorothiazolo[5,4-d]pyrimidine;Thiazolo[5,4-d]pyrimidine, 5,7-dichloro-;5,7-dichloro-[1,3]thiazolo[5,4-d]pyriMidine
CBNumber:
CB31483436
Molecular Formula:
C5HCl2N3S
Molecular Weight:
206.05
MDL Number:
MFCD09702027
MOL File:
13479-88-4.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:41
Product description Number Pack Size Price
5,7-Dichlorothiazolo[5,4-d]pyrimidine D436463 100mg $105
5,7-Dichlorothiazolo[5,4-d]pyrimidine FD142325 100mg $142
5,7-Dichlorothiazolo[5,4-d]pyrimidine FD142325 50mg $82
5,7-Dichlorothiazolo[5,4-d]pyrimidine X9888 250mg $262
5,7-Dichlorothiazolo[5,4-d]pyrimidine FD142325 250mg $282.5
More product size
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5,7-dichlorothiazolo[5,4-d]pyrimidine Properties

Melting point 148.5-149.5 °C
Boiling point 281.2±22.0 °C(Predicted)
Density 1.767±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMF: 2 mg/ml,DMSO: 1 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
form A solid
pka -2.68±0.50(Predicted)
color Light yellow to brown
InChI InChI=1S/C5HCl2N3S/c6-3-2-4(11-1-8-2)10-5(7)9-3/h1H
InChIKey XYBGDWLYHQAUQM-UHFFFAOYSA-N
SMILES C1(Cl)=NC(Cl)=C2N=CSC2=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
NFPA 704
0
2 0

5,7-dichlorothiazolo[5,4-d]pyrimidine price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D436463 5,7-Dichlorothiazolo[5,4-d]pyrimidine 13479-88-4 100mg $105 2021-12-16 Buy
Biosynth Carbosynth FD142325 5,7-Dichlorothiazolo[5,4-d]pyrimidine 13479-88-4 100mg $142 2021-12-16 Buy
Biosynth Carbosynth FD142325 5,7-Dichlorothiazolo[5,4-d]pyrimidine 13479-88-4 50mg $82 2021-12-16 Buy
AK Scientific X9888 5,7-Dichlorothiazolo[5,4-d]pyrimidine 13479-88-4 250mg $262 2021-12-16 Buy
Biosynth Carbosynth FD142325 5,7-Dichlorothiazolo[5,4-d]pyrimidine 13479-88-4 250mg $282.5 2021-12-16 Buy
Product number Packaging Price Buy
D436463 100mg $105 Buy
FD142325 100mg $142 Buy
FD142325 50mg $82 Buy
X9888 250mg $262 Buy
FD142325 250mg $282.5 Buy

5,7-dichlorothiazolo[5,4-d]pyrimidine Chemical Properties,Uses,Production

Uses

5,7-Dichlorothiazolo[5,4-d]pyrimidine was used in studies to prepare Kinase inhibitors.

Synthesis

thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione

5082-82-6

5,7-dichlorothiazolo[5,4-d]pyrimidine

13479-88-4

The general procedure for the synthesis of 5,7-dichlorothiazolo[5,4-d]pyrimidine using thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione as starting material was as follows: a 10 mL round bottom flask was charged with intermediate 45.2 (100 mg, 0.59 mmol, 1.00 equiv.), N,N-diisopropylethylamine (DIEA, 0.5 mL) and phosphorus oxychloride (POCl3, 2 mL). The reaction mixture was stirred at 100 °C for 12 hours. After completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The crude product was purified by fast column chromatography to afford intermediate 45.3 (100 mg, 82% yield) as a yellow oil.

References

[1] Heterocycles, 2012, vol. 85, # 7, p. 1721 - 1726
[2] Patent: WO2015/48281, 2015, A1. Location in patent: Paragraph 00472; 00475
[3] Patent: WO2014/15291, 2014, A1. Location in patent: Page/Page column 168; 169
[4] Journal of the American Chemical Society, 1951, vol. 73, p. 3862

5,7-dichlorothiazolo[5,4-d]pyrimidine Preparation Products And Raw materials

Raw materials

thiazolo[5,4-d]pyrimidine-5,7(4H,6H)-dione

Preparation Products

5,7-dichlorothiazolo[5,4-d]pyrimidine Suppliers

Global( 121)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29850 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 3999 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58

View Lastest Price from 5,7-dichlorothiazolo[5,4-d]pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5,7-dichlorothiazolo[5,4-d]pyriMidine pictures 2020-05-17 5,7-dichlorothiazolo[5,4-d]pyriMidine
13479-88-4
 US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
5,7-dichlorothiazolo[5,4-d]pyrimidine pictures 2019-07-06 5,7-dichlorothiazolo[5,4-d]pyrimidine
13479-88-4
 US $1.00 / kg 1kg 97%-99% as request Career Henan Chemical Co

5,7-dichlorothiazolo[5,4-d]pyrimidine Spectrum

5,7-dichlorothiazolo[5,4-d]pyrimidine(13479-88-4)1HNMR

13479-88-4(5,7-dichlorothiazolo[5,4-d]pyrimidine)Related Search:

5,7-dichlorothiazolo[5,4-d]pyrimidine
5,7-dichloro-[1,3]thiazolo[5,4-d]pyriMidine 5,7-dichlorothiazolo[5,4-d]pyrimidine Thiazolo[5,4-d]pyrimidine, 5,7-dichloro- 13479-88-4 Heterocycle-Pyrimidine series