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H-SER-PHE-LEU-LEU-ARG-OH

CAS No.
141685-53-2
Chemical Name:
H-SER-PHE-LEU-LEU-ARG-OH
Synonyms
SFLLR;SER-PHE-LEU-LEU-ARG;H-SER-PHE-LEU-LEU-ARG-OH;Thrombin Receptor Activator for Peptide 5 (TRAP-5);L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginine;L-Arginine, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-;SFLLR, Coagulation Factor II Receptor (1-5) (huMan), PAR-1 (1-5) (huMan), ThroMbin Receptor (1-5) (huMan), ThroMbin Receptor Activator Peptide 5, Proteinase Activated Receptor 1 (1-5) (huMan)
CBNumber:
CB3151835
Molecular Formula:
C30H50N8O7
Molecular Weight:
634.77
MDL Number:
MFCD00238174
MOL File:
141685-53-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:30
Product description Number Pack Size Price
TRAP-5 trifluoroacetate salt FT108440 2000ug $900
H-Ser-Phe-Leu-Leu-Arg-OH PAR-3936-PI 1mg $150
TRAP-5 trifluoroacetate salt FT108440 1000ug $900
H-Ser-Phe-Leu-Leu-Arg-OH PAR-3936-PI 5mg $389.5
TRAP-5 trifluoroacetate salt FT108440 500ug $900

H-SER-PHE-LEU-LEU-ARG-OH Properties

Density 1.32±0.1 g/cm3(Predicted)
storage temp. -15°C
solubility insoluble in EtOH; ≥14.63 mg/mL in H2O; ≥63.5 mg/mL in DMSO
form solid
pka 3.34±0.10(Predicted)

H-SER-PHE-LEU-LEU-ARG-OH price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FT108440 TRAP-5 trifluoroacetate salt 141685-53-2 2000ug $900 2026-06-04 Buy
Biosynth PAR-3936-PI H-Ser-Phe-Leu-Leu-Arg-OH 141685-53-2 1mg $150 2026-06-04 Buy
Biosynth FT108440 TRAP-5 trifluoroacetate salt 141685-53-2 1000ug $900 2026-06-04 Buy
Biosynth PAR-3936-PI H-Ser-Phe-Leu-Leu-Arg-OH 141685-53-2 5mg $389.5 2026-06-04 Buy
Biosynth FT108440 TRAP-5 trifluoroacetate salt 141685-53-2 500ug $900 2026-06-04 Buy
Product number Packaging Price Buy
FT108440 2000ug $900 Buy
PAR-3936-PI 1mg $150 Buy
FT108440 1000ug $900 Buy
PAR-3936-PI 5mg $389.5 Buy
FT108440 500ug $900 Buy

H-SER-PHE-LEU-LEU-ARG-OH Chemical Properties,Uses,Production

Uses

Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD).

Biological Activity

thrombin receptor activator for peptide 5 (trap-5),(c30h50n8o7), a peptide with the sequence nh2-ser-phe-leu-leu-arg-cooh, mw= 634.76. coagulation factor ii (thrombin) receptor is a g protein-coupled receptor involved in the regulation of thrombotic response. proteolytic cleavage leads to the activation of the receptor(1). thrombin signalling in platelets contributes to hemostasis and thrombosis. endothelial pars participate in the regulation of vascular tone and permeability while in vascular smooth muscle they mediate contraction, proliferation, and hypertrophy. pars contribute to the pro-inflammatory response observed in atherosclerosis and restenosis. recent research has also implicated these novel receptors in muscle growth and bone cell differentiation and proliferation(2). in t cells, activation of par1, par2 and par3 induce tyrosine phosphorylation of vav1. activation of pars also led to an increase in tyrosine phosphorylation of zap-70 and slp-76, two key proteins in t cell receptor (tcr) signalling(3).figure1 formula of thrombin receptor activator for peptide 5 (trap-5)figure2 structure of thrombin receptor

References

1. Bahou WF, Nierman WC, Durkin AS, Potter CL, Demetrick DJ (September 1993). "Chromosomal assignment of the human thrombin receptor gene: localization to region q13 of chromosome 5". Blood 82 (5): 1532–7.2. Martorell L, Martínez-González J, Rodríguez C, Gentile M, Calvayrac O, Badimon L (February 2008). "Thrombin and protease-activated receptors (PARs) in atherothrombosis". Thromb. Haemost. 99 (2): 305–15.3. Bar-Shavit R, Maoz M, Yongjun Y, Groysman M, Dekel I, Katzav S (January 2002). "Signalling pathways induced by protease-activated receptors and integrins in T cells". Immunology 105 (1): 35–46.

H-SER-PHE-LEU-LEU-ARG-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-SER-PHE-LEU-LEU-ARG-OH Suppliers

Global( 105)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10403 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19853 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471; sales@sarms4muscle.com China 10473 58
Hangzhou Go Top Peptide Biotech
0571-88211921 sales1@gotopbio.com CHINA 2609 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Alfa Chemistry
+1-5166625404; Info@alfa-chemistry.com United States 20405 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
Henan Aochuang Chemical Co.,Ltd.
+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9333 58

View Lastest Price from H-SER-PHE-LEU-LEU-ARG-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-SER-PHE-LEU-LEU-ARG-OH pictures 2025-04-04 H-SER-PHE-LEU-LEU-ARG-OH
141685-53-2
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
 H-SER-PHE-LEU-LEU-ARG-OH pictures 2020-02-14 H-SER-PHE-LEU-LEU-ARG-OH
141685-53-2
$7.00 1KG 99% 100kg Career Henan Chemical Co

H-SER-PHE-LEU-LEU-ARG-OH Spectrum

H-SER-PHE-LEU-LEU-ARG-OH SFLLR, Coagulation Factor II Receptor (1-5) (huMan), PAR-1 (1-5) (huMan), ThroMbin Receptor (1-5) (huMan), ThroMbin Receptor Activator Peptide 5, Proteinase Activated Receptor 1 (1-5) (huMan) SFLLR SER-PHE-LEU-LEU-ARG Thrombin Receptor Activator for Peptide 5 (TRAP-5) L-Arginine, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl- L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginine 141685-53-2 C30H50N8O7 Peptide Cardiovescular