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ChemicalBook >> CAS DataBase List >>5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole Structure
5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole structure
CAS No.
524-81-2
Chemical Name:
5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
Synonyms
Mebhydroline;MEBHYDROLIN;Mebhydrin.;Mebhydrolin, 10 mM in DMSO;N-Methyl-9-benzyltetrahydro-γ-carboline;Mebhydrolin,inhibit,Histamine Receptor,Inhibitor;3-Benzyl-6-methyl-1,2,3,4-tetrahydro-gamma-carboline;5-benzyl-2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indole;5-benzyl-1,2,3,4-tetrahydro-2-methylpyrido(4,3-b)indole;5-Benzyl-1,3,4,5-tetrahydro-2-methyl-2H-pyrido[4,3-b]indole
CBNumber:
CB3167173
Molecular Formula:
C19H20N2
Molecular Weight:
276.38
MDL Number:
MFCD00865679
MOL File:
524-81-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:51:44
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5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole Properties

Melting point 95°
Boiling point bp1 207-215°
Density 1.0246 (rough estimate)
refractive index 1.5640 (estimate)
storage temp. Store at -20°C
solubility DMSO : 83.33 mg/mL (301.51 mM)
form Solid
pka pKa 2.55 ± 0.18;7.63± 0.04(H2O,t undefined,I=0.30(NaCl)) (Uncertain)
color White to off-white
FDA UNII 9SUK9B7XVY
ATC code R06AX15

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
REACH Registrations Active

5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth AAA52481 Mebhydrolin 524-81-2 2.5g $500 2026-06-04 Buy
ChemScene CS-0013654 Mebhydrolin 99.33% 524-81-2 100mg $52 2026-06-04 Buy
ChemScene CS-0013654 Mebhydrolin 99.33% 524-81-2 500mg $173 2026-06-04 Buy
Matrix Scientific 310565 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 524-81-2 1.00g $58 2026-05-19 Buy
Matrix Scientific 310565 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 524-81-2 5.00g $208 2026-05-19 Buy
Product number Packaging Price Buy
AAA52481 2.5g $500 Buy
CS-0013654 100mg $52 Buy
CS-0013654 500mg $173 Buy
310565 1.00g $58 Buy
310565 5.00g $208 Buy

5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole Chemical Properties,Uses,Production

Uses

Mebhydrolin is a specific histamine H1 receptor antagonist.

Definition

ChEBI: Mebhydrolin is a member of indoles.

References

[1] O'Neill PA, et al. Chlorpromazine-a specific effect on breathlessness Br J Clin Pharmacol. 1985 Jun;19(6):793-7. DOI:10.1111/j.1365-2125.1985.tb02716.x
[2] Franks HM, et al. Interaction between ethanol and antihistamines: 3. Mebhydrolin. Med J Aust. 1981 Oct 31;2(9):477-9. DOI:10.5694/j.1326-5377.1981.tb112944.x

5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole synthesis

34737-83-2
614-31-3
524-81-2
Synthesis of 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole from 1-Methyl-4-piperidinol hydrochloride and 1-Benzyl-1-phenylhydrazine

5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole Preparation Products And Raw materials

Raw materials

1-Benzyl-1-phenylhydrazine 1-Methyl-4-piperidinol hydrochloride Benzyl chloride 1-Methyl-4-piperidone

Preparation Products

5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole Suppliers

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Shanghai Brain Biotechnology Co., Ltd. 13564638271 shhjiang1977@163.com China 2985 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Changzhou Hopschain Chemical Co.,Ltd. 85528066 13775048983 sales@hopschem.com China 31548 55
Dayang Chem (Hangzhou) Co.,Ltd. +86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
AFINE CHEMICALS LIMITED +86-571-85134551 +86-18958018566 info@afinechem.com China 15030 58
Shanghai TenSus Biotechnology Co., Ltd. 021-50895067 18616507272;13681616114;15020344067 tensus@163.com China 8029 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Shaanxi Dideu Medichem Co. Ltd +86-29-87569266 +86-17392581500 1015@dideu.com China 3861 58
Shanghai Luofa Biochemical Technology Co., Ltd. 021-51111890 15317326293 sales@molnova.com China 4183 58
Supplier Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai Brain Biotechnology Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Changzhou Hopschain Chemical Co.,Ltd. 55
Dayang Chem (Hangzhou) Co.,Ltd. 58
AFINE CHEMICALS LIMITED 58
Shanghai TenSus Biotechnology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shaanxi Dideu Medichem Co. Ltd 58
Shanghai Luofa Biochemical Technology Co., Ltd. 58

View Lastest Price from 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE pictures 2026-06-30 5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE
524-81-2
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd

5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole Spectrum

5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE(524-81-2)1HNMR

524-81-2(5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole)Related Search:

Benzene/toluene Mesitylene 1,2,4-Trimethylbenzene Tosyl chloride 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
1-Methyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine 2-Methyl-3-N,N-dimethylaminomethylindole Mebhydrolin napadisylate (1-Methyl-1H-indol-3-yl)-methylamine 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indole

1of2

2,3,4,5-Tetrahydro-2-methyl-5-(phenylmethyl)-1H-pyrido[4,3-b]indole 2,3,4,5-Tetrahydro-2-methyl-5-phenylmethyl-1H-pyrido[4,3-b]indole N-Methyl-9-benzyltetrahydro-γ-carboline 1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2-methyl-5-(phenylmethyl)- 3-Benzyl-6-methyl-1,2,3,4-tetrahydro-gamma-carboline 5-Benzyl-1,3,4,5-tetrahydro-2-methyl-2H-pyrido[4,3-b]indole 5-benzyl-1,2,3,4-tetrahydro-2-methylpyrido(4,3-b)indole 5-benzyl-2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indole Mebhydrolin,inhibit,Histamine Receptor,Inhibitor Mebhydrolin, 10 mM in DMSO Mebhydrin. MEBHYDROLIN Mebhydroline 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 524-81-2 Intermediates of Sertraline