Butyrophenone
- CAS No.
- 495-40-9
- Chemical Name:
- Butyrophenone
- Synonyms
- 1-Phenylbutan-1-one;1-PHENYL-1-BUTANONE;Butanophenone;1-phenyl-1-butanon;Propyl phenyl ketone;BUTYROPHENONE;Buterophenone;Buthrophenone;Butyrylbenzene;N-BUTYROPHENONE
- CBNumber:
- CB3167698
- Molecular Formula:
- C10H12O
- Molecular Weight:
- 148.2
- MDL Number:
- MFCD00009397
- MOL File:
- 495-40-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 11-13 °C(lit.) |
|---|---|
| Boiling point | 228-230 °C(lit.) |
| Density | 1.021 g/mL at 25 °C(lit.) |
| refractive index |
n |
| FLAVIS Number | 07.193 | 1-Phenylbutan-1-one |
| Flash point | 192 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Liquid |
| Specific Gravity | 0.988 |
| color | Clear colorless to yellow |
| Odor | at 100.00 %. camphor cherry walnut hazelnut |
| Odor Type | camphoreous |
| biological source | synthetic |
| Water Solubility | Insoluble in water. |
| BRN | 508305 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Cosmetics Ingredients Functions | PERFUMING |
| InChI | 1S/C10H12O/c1-2-6-10(11)9-7-4-3-5-8-9/h3-5,7-8H,2,6H2,1H3 |
| InChIKey | FFSAXUULYPJSKH-UHFFFAOYSA-N |
| SMILES | CCCC(=O)c1ccccc1 |
| LogP | 2.770 |
| CAS DataBase Reference | 495-40-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 186I11WB5B |
| NIST Chemistry Reference | 1-Butanone, 1-phenyl-(495-40-9) |
| EPA Substance Registry System | 1-Butanone, 1-phenyl- (495-40-9) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H317-H318-H227 | |||||||||
| Precautionary statements | P210-P370+P378-P403+P235-P501-P280-P305+P351+P338-P305+P351+P338+P310-P333+P313-P210e-P280a-P370+P378a-P501a | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 41-43 | |||||||||
| Safety Statements | 26-36/37/39-24/25-23 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29143900 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
Butyrophenone price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 124338 | Butyrophenone ≥99% | 495-40-9 | 25g | $64.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 124338 | Butyrophenone ≥99% | 495-40-9 | 100g | $238 | 2026-04-30 | Buy |
| TCI Chemical | B0769 | Butyrophenone >99.0%(GC) | 495-40-9 | 25mL | $38 | 2026-04-30 | Buy |
| TCI Chemical | B0769 | Butyrophenone >99.0%(GC) | 495-40-9 | 100mL | $116 | 2026-04-30 | Buy |
| Biosynth | FP66953 | Phenyl-N-propyl ketone | 495-40-9 | 0.1kg | $217.68 | 2026-06-04 | Buy |
Butyrophenone Chemical Properties, Uses, Production
Description
Butyrophenone is a chemical compound with the formula C10H12O. Butyrophenone has been used to study the relationship between the electrolyte counter-ion concentration and the critical micelle concentration for several surfactants. It has been used to generate PhCO+ ions by 70 eV electron ionization. Some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics. They can interfere with neurotransmitter functions, usually blocking dopamine receptors, and induce behavioral, endocrine, motor-kinetic effects. Examples of butyrophenones include: Haloperidol, the most widely used classical antipsychotic drug in this class; Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine).
References
1. https://en.wikipedia.org/wiki/Butyrophenone
2. http://www.rightdiagnosis.com/medical/butyrophenone.htm
3. http://www.sigmaaldrich.com/catalog/product/aldrich/124338?lang=en®ion=CA
Chemical Properties
colourless to yellow liquid
Uses
Butyrophenone is used as intermediates of Liquid Crystals
Uses
Intermediates of Liquid Crystals
Synthesis Reference(s)
The Journal of Organic Chemistry, 61, p. 376, 1996 DOI: 10.1021/JO951500R
Tetrahedron Letters, 30, p. 6357, 1989 DOI: 10.1016/S0040-4039(01)93893-6
Biochem/physiol Actions
Butyrophenones constitutes neuroleptic drugs and interacts with the opiate receptor by inhibiting the stereospecific binding of 3H-naloxone.
Butyrophenone Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Weifang QianJin Fine Chemical Co., Ltd. | 18753684562 | 1577399715@qq.COM | China | 1772 | 55 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
View Latest Price from Butyrophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | Butyrophenone
495-40-9
|
$1.00 | 300g | 99.8% | 20 TONS | .GZ HONESTCHEM CO.,LTD | |
 |
2026-05-11 | Butyrophenone
495-40-9
|
99.84% | 10g | TargetMol Chemicals Inc. | |||
 |
2026-03-20 | Butyrophenone
495-40-9
|
$10.00 | 1KG | 99.5% | 100 | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Butyrophenone
495-40-9
- $1.00
- 99.8%
- .GZ HONESTCHEM CO.,LTD
-
- Butyrophenone
495-40-9
- $0.00
- 99.84%
- TargetMol Chemicals Inc.
-
- Butyrophenone
495-40-9
- $10.00
- 99.5%
- Hebei Chuanghai Biotechnology Co., Ltd
