ChemicalBook >> CAS DataBase List >>Butyrophenone

Butyrophenone

CAS No.
495-40-9
Chemical Name:
Butyrophenone
Synonyms
1-Phenylbutan-1-one;Butanophenone;1-PHENYL-1-BUTANONE;Propyl phenyl ketone;BUTYROPHENONE;Buterophenone;Buthrophenone;Butyrylbenzene;N-BUTYROPHENONE;N-BUTANOPHENONE
CBNumber:
CB3167698
Molecular Formula:
C10H12O
Molecular Weight:
148.2
MDL Number:
MFCD00009397
MOL File:
495-40-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 16:31:51
Product description Number Pack Size Price
Butyrophenone ≥99% 124338 25g $64.7
Butyrophenone ≥99% 124338 100g $238
Butyrophenone >99.0%(GC) B0769 25mL $38
Butyrophenone >99.0%(GC) B0769 100mL $116
Butyrophenone analytical standard 16704 1ml $92
More product size

Butyrophenone Properties

Melting point 11-13 °C(lit.)
Boiling point 228-230 °C(lit.)
Density 1.021 g/mL at 25 °C(lit.)
FLAVIS Number 07.193 | 1-Phenylbutan-1-one
refractive index n20/D 1.520(lit.)
Flash point 192 °F
storage temp. Store below +30°C.
solubility Chloroform (Slightly), Methanol (Slightly)
form Liquid
color Clear colorless to yellow
Specific Gravity 0.988
Odor at 100.00 %. camphor cherry walnut hazelnut
Odor Type camphoreous
biological source synthetic
Water Solubility Insoluble in water.
BRN 508305
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions PERFUMING
InChI 1S/C10H12O/c1-2-6-10(11)9-7-4-3-5-8-9/h3-5,7-8H,2,6H2,1H3
InChIKey FFSAXUULYPJSKH-UHFFFAOYSA-N
SMILES CCCC(=O)c1ccccc1
LogP 2.770
CAS DataBase Reference 495-40-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 186I11WB5B
NIST Chemistry Reference 1-Butanone, 1-phenyl-(495-40-9)
EPA Substance Registry System 1-Butanone, 1-phenyl- (495-40-9)
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H317-H318-H227
Precautionary statements  P210-P370+P378-P403+P235-P501-P280-P305+P351+P338-P305+P351+P338+P310-P333+P313-P210e-P280a-P370+P378a-P501a
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  41-43
Safety Statements  26-36/37/39-24/25-23
WGK Germany  3
TSCA  TSCA listed
HS Code  29143900
Storage Class 10 - Combustible liquids
NFPA 704
2
0 0

Butyrophenone price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 124338 Butyrophenone ≥99% 495-40-9 25g $64.7 2026-04-30 Buy
Sigma-Aldrich 124338 Butyrophenone ≥99% 495-40-9 100g $238 2026-04-30 Buy
TCI Chemical B0769 Butyrophenone >99.0%(GC) 495-40-9 25mL $38 2026-04-30 Buy
TCI Chemical B0769 Butyrophenone >99.0%(GC) 495-40-9 100mL $116 2026-04-30 Buy
Sigma-Aldrich 16704 Butyrophenone analytical standard 495-40-9 1ml $92 2026-04-30 Buy
Product number Packaging Price Buy
124338 25g $64.7 Buy
124338 100g $238 Buy
B0769 25mL $38 Buy
B0769 100mL $116 Buy
16704 1ml $92 Buy

Butyrophenone Chemical Properties,Uses,Production

Description

Butyrophenone is a chemical compound with the formula C10H12O. Butyrophenone has been used to study the relationship between the electrolyte counter-ion concentration and the critical micelle concentration for several surfactants. It has been used to generate PhCO+ ions by 70 eV electron ionization. Some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics. They can interfere with neurotransmitter functions, usually blocking dopamine receptors, and induce behavioral, endocrine, motor-kinetic effects. Examples of butyrophenones include: Haloperidol, the most widely used classical antipsychotic drug in this class; Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine).

References

1. https://en.wikipedia.org/wiki/Butyrophenone
2. http://www.rightdiagnosis.com/medical/butyrophenone.htm
3. http://www.sigmaaldrich.com/catalog/product/aldrich/124338?lang=en&region=CA

Chemical Properties

colourless to yellow liquid

Uses

Butyrophenone is used as intermediates of Liquid Crystals

Uses

Intermediates of Liquid Crystals

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 376, 1996 DOI: 10.1021/JO951500R
Tetrahedron Letters, 30, p. 6357, 1989 DOI: 10.1016/S0040-4039(01)93893-6

Biochem/physiol Actions

Butyrophenones constitutes neuroleptic drugs and interacts with the opiate receptor by inhibiting the stereospecific binding of 3H-naloxone.

622-76-4
495-40-9
Synthesis of Butyrophenone from 1-PHENYL-1-BUTYNE
Global( 275)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29817 58
QINGDAO HONG JIN CHEMCIAL CO.,LTD.
+86-86-532-83657313 +86-18663969289 hjt@hong-jin.com China 225 58
Jinan Shengqi pharmaceutical Co,Ltd
86+18663751872 christine@shengqipharm.com CHINA 491 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
Shanghai Longyu Biotechnology Co., Ltd.
+8619521488211 info@longyupharma.com China 2542 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58

View Lastest Price from Butyrophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Butyrophenone pictures 2026-05-11 Butyrophenone
495-40-9
US $0.00 / removed 99.84% 10g TargetMol Chemicals Inc.
Butyrophenone pictures 2026-03-20 Butyrophenone
495-40-9
US $10.00 / KG 1KG 99.5% 100 Hebei Chuanghai Biotechnology Co., Ltd
Butyrophenone, Phenyl n-propyl ketone pictures 2021-07-02 Butyrophenone, Phenyl n-propyl ketone
495-40-9
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • Butyrophenone pictures
  • Butyrophenone
    495-40-9
  • US $0.00 / removed
  • 99.84%
  • TargetMol Chemicals Inc.
  • Butyrophenone pictures
  • Butyrophenone
    495-40-9
  • US $10.00 / KG
  • 99.5%
  • Hebei Chuanghai Biotechnology Co., Ltd
1-PHENYL-1-BUTANONE 1-Butanone,1-phenyl- 1-phenyl-1-butanon 1-phenyl-butan-1-one 1-Phenylbutan-1-one Butyrylbenzene Propyl phenyl ketone N-BUTANOPHENONE N-BUTYROPHENONE N-PROPYL PHENYL KETONE PHENYL PROPYL KETONE PHENYL N-PROPYL KETONE BUTYROPHENONE, 99+% N-BUTYROPHENONE 99% n-butyrophenone, phenyl-n-propyl ketone BUTYROPHENONE Butanophenone n-Butyrophenone,99% 1-Phenylbutan-1-one, Phenyl propyl ketone n-Butyrophenone, 99% 100ML Buterophenone Butyrophenone, Phenyl n-propyl ketone Naproxen Impurity 9 Butyrophenone > BUTYROPHENONE FOR SYNTHESIS 250 ML BUTYROPHENONE FOR SYNTHESIS 25 ML Naproxen Impurity 37 Butyrophenone, puriss, 99%+ Butyrophenone, puriss Butyrophenone (6CI, 8CI) BORON TRIBROMIDE 1M in N-Heptane Butyrophenone, 99% (Custom work) Buthrophenone Butyrophenone, ≥ 99.0% n-Butyrophenone Solution in Methanol benzenebutylone 495-40-9 C6H5COCH2CH2CH3 C2H5CH2COC6H5 C3H7COC6H5 CH3CH2CH2COC6H5 Organic Building Blocks Ketones Building Blocks Carbonyl Compounds C10 KETONE Building Blocks C10 Carbonyl Compounds Chemical Synthesis Ketones Organic Building Blocks Pharmaceutical Intermediates Aromatic Ketones (substituted) ketone