2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride
- CAS No.
- 78667-04-6
- Chemical Name:
- 2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride
- Synonyms
- 2-Chloromethyl-1-methyl-1H-imida;2-CHLOROMETHYL-1-METHYL-1H-IMIDAZOLE HCL;2-(Chloromethyl)-1-methylimidazole hydrochloride;1-Methyl-2-(chloromethyl)imidazole hydrochloride;2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride;2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 95%;1H-IMidazole,2-(chloroMethyl)-1-Methyl-, hydrochloride (1:1)
- CBNumber:
- CB3168271
- Molecular Formula:
- C5H8Cl2N2
- Molecular Weight:
- 167.04
- MDL Number:
- MFCD00234118
- MOL File:
- 78667-04-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| HS Code | 2933299090 | |||||||||
| NFPA 704 |
|
2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS74608 | 2-Chloromethyl-1-methyl-1H-imidazole HCl 98% | 78667-04-6 | 1g | $51 | 2026-06-04 | Buy |
| Activate Scientific | AS74608 | 2-Chloromethyl-1-methyl-1H-imidazole HCl 98% | 78667-04-6 | 5g | $161 | 2026-06-04 | Buy |
| Apolloscientific | OR40445 | 2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 95% | 78667-04-6 | 250mg | $21 | 2026-06-04 | Buy |
| AK Scientific | Y4093 | 2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 98%(GC) | 78667-04-6 | 1g | $35 | 2026-06-04 | Buy |
| AK Scientific | Y4093 | 2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 98%(GC) | 78667-04-6 | 5g | $114 | 2026-06-04 | Buy |
2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride Chemical Properties, Uses, Production
Synthesis
17334-08-6
78667-04-6
General procedure for the synthesis of 2-(chloromethyl)-1-methyl-1H-imidazole hydrochloride (BB7) from 1-methyl-2-hydroxymethyl-1H-imidazole (BB6): to a solution of BB6 (35.5 g, 316.96 mmol) in dichloromethane (DCM, 1500 mL) was slowly added thionyl chloride (SOCl2, 330 mL, 4436 mmol ). The reaction mixture was gradually warmed to room temperature and stirred continuously for 5 hours. Upon completion of the reaction, the mixture was concentrated to remove the solvent. The residue was washed sequentially with dichloromethane (DCM, 2 × 500 mL) and ether (Et2O, 2 × 200 mL) to give the final target product BB7 (50 g, 95% yield) as an off-white solid. Thin-layer chromatography (TLC) showed an Rf value of 0.4 (unfolding agent: ethyl acetate).1H NMR (400 MHz, DMSO-d6) data were as follows: δ 7.76 (1H, apparent double peaks), 7.70 (1H, apparent double peaks), 5.17 (2H, single peak), 3.87 (3H, single peak); mass spectrometry (MS) showed an m/z of 131 ([M+H]+ ).
References
[1] Patent: US2012/322722, 2012, A1
[2] Tetrahedron Letters, 2011, vol. 52, # 41, p. 5308 - 5310
[3] Tetrahedron, 1996, vol. 52, # 48, p. 15171 - 15188
[4] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993, # 19, p. 2291 - 2302
[5] Tetrahedron Letters, 2013, vol. 54, # 45, p. 6087 - 6089
2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Acorn PharmaTech Co., Ltd. | 025-58395930 | sales@acornpharma.com | China | 982 | 60 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Nanjing YiFan Biological Technology Co., Ltd. | 025-025-52700520 18914499889 | sales@yfbiotech.com | China | 494 | 58 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8135 | 55 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Nanjing Chemcn Pharmaceutical Co., Ltd. | 18114022054; 18114022054 | 3317707757@qq.com | China | 301 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
View Latest Price from 2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-03 | 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE
78667-04-6
|
$6.60 | 1KG | 97%-99% | 1kg -1000kg | Career Henan Chemical Co |
-
- 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE
78667-04-6
- $6.60
- 97%-99%
- Career Henan Chemical Co
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