ChemicalBook >> CAS DataBase List >>N-Methylolacrylamide
N-Methylolacrylamide
- CAS No.
- 924-42-5
- Chemical Name:
- N-Methylolacrylamide
- Synonyms
- N-(HYDROXYMETHYL)ACRYLAMIDE;METHYLOLACRYLAMIDE;N-MAN;N-MAN PC;N-Methanolacrylamide;HINT;NM-AMD;PRKCNH1;uraminet80;Rocagil BT
- CBNumber:
- CB3182194
- Molecular Formula:
- C4H7NO2
- Molecular Weight:
- 101.1
- MDL Number:
- MFCD00004597
- MOL File:
- 924-42-5.mol
- MSDS File:
- SDS
Last updated:2026-06-24 18:39:39
| Melting point | 74-75°C |
|---|---|
| Boiling point | 277°C(lit.) |
| Density | 1.082 g/mL at 20 °C |
| vapor pressure | 31 hPa (25 °C) |
| refractive index |
n |
| Flash point | 100°C |
| storage temp. | Store at <= 20°C. |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 13.25±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| Specific Gravity | 1.074 |
| PH | 6.0-7.0 (H2O, 20°C) |
| Water Solubility | <0.1 g/100 mL at 20.5 ºC |
| BRN | 506646 |
| Stability | Light Sensitive, Moisture Sensitive |
| InChI | 1S/C4H7NO2/c1-2-4(7)5-3-6/h2,6H,1,3H2,(H,5,7) |
| InChIKey | CNCOEDDPFOAUMB-UHFFFAOYSA-N |
| SMILES | OCNC(=O)C=C |
| LogP | -1.81 at 20℃ and pH7 |
| Toxicology and Carcinogenesis | Toxicology and Carcinogenesis Studies of N-Methylolacrylamide (CASRN 924-42-5) in F344/N Rats and B6C3F1 Mice |
| Substances of Very High Concern (SVHC) Candidate List | N-(hydroxymethyl)acrylamide (924-42-5) |
| FDA 21 CFR | 175.105; 176.170; 176.180;177.1010; 177.2260 |
| Indirect Additives used in Food Contact Substances | N-METHYLOLACRYLAMIDE |
| CAS DataBase Reference | 924-42-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | W8W68JL80Q |
| Proposition 65 List | n-Methylolacrylamide |
| NIST Chemistry Reference | 2-Propenamide, n-(hydroxymethyl)-(924-42-5) |
| IARC | 3 (Vol. 60) 1994 |
| EPA Substance Registry System | N-Methylolacrylamide (924-42-5) |
| UNSPSC Code | 12352111 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H317-H340-H350-H361-H372-H373 | |||||||||
| Precautionary statements | P202-P260-P264-P280-P301+P310-P302+P352 | |||||||||
| target organs | Peripheral nervous system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn,T | |||||||||
| Risk Statements | 22-36/37/38-62-48/20/21/22-43-46-45 | |||||||||
| Safety Statements | 26-45-36/37-53 | |||||||||
| RIDADR | 2810 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AS3600000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 4.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29241990 | |||||||||
| Storage Class | 6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Carc. 1B Muta. 1B Repr. 2 Skin Sens. 1 STOT RE 1 STOT RE 2 Oral |
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| Hazardous Substances Data | 924-42-5(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
N-Methylolacrylamide price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.20675 | N-(Hydroxymethyl)acrylamide (48% aqueous solution) (stabilised with hydroquinone monomethyl ether) for synthesis | 924-42-5 | 100mL | $44.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 245801 | N-(Hydroxymethyl)acrylamide solution 48 wt. % in H2O | 924-42-5 | 100g | $98.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 245801 | N-(Hydroxymethyl)acrylamide solution 48 wt. % in H2O | 924-42-5 | 1kg | $171 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.20675 | N-(Hydroxymethyl)acrylamide (48% aqueous solution) (stabilised with hydroquinone monomethyl ether) for synthesis | 924-42-5 | 1L | $69.2 | 2024-03-01 | Buy |
| TCI Chemical | M0574 | N-(Hydroxymethyl)acrylamide >98.0%(T) | 924-42-5 | 25g | $27 | 2026-04-30 | Buy |
N-Methylolacrylamide Chemical Properties, Uses, Production
Chemical Properties
White solid
Uses
N-(Hydroxymethyl)acrylamide can be used as:
- A monomer in the development of polymer gel dosimeters specifically designed for radiation therapy applications. The incorporation of NHMA enhances the sensitivity of the dosimeter to radiation doses.
- A monomer in the development of thermo-responsive polymeric gates, which exhibits thermo-responsive behavior. The incorporation of NHMA enhances the overall properties of the polymer, allowing for better control over the release mechanisms in response to temperature changes.
- A key monomer in the synthesis of double-hydrophilic and amphiphilic block glycopolymers, contributing to their self-assembly properties, biocompatibility, and functionalization potential. These characteristics make NHMA-based glycopolymers valuable for various biomedical applications, including drug delivery systems, biosensors, and tissue engineering.
Definition
ChEBI: N-Methylolacrylamide is a secondary carboxamide.
General Description
A colorless or yellow aqueous solution.
Air & Water Reactions
Soluble in water.
Reactivity Profile
N-Methylolacrylamide may be sensitive to prolonged exposure to light. Polymerization and generation of heat and flames may occur on exposure to to heat or contaminants. Incompatible with strong oxidizers.
Fire Hazard
Literature sources indicate that N-Methylolacrylamide is nonflammable.
Synthesis
(1), the acrylamide is added to the reaction kettle containing solvent acetone, the polymerization blocking agent is added, and the temperature is raised to 4245;
(2), adding catalyst sodium methanol, adjusting the pH value in the reaction solution to 8.88;
(3), adding formaldehyde, adjusting the pH of the reaction solution to 8.5, and reacting at constant temperature for 1 hour;
(4), add phthalic acid, adjust its reaction solution pH to 7.2;
(5), cooling, crystallization, filtration to get the finished product N-hydroxymethacrylamide.
N-Methylolacrylamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 464)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Baidu Chemical Co., Ltd | 027-59106051 13627137652 | 1438180055@qq.com | China | 8469 | 58 |
| Jinan Aoxiang Chemical Industry Co. , Ltd. | 18354135979 | 970731907@qq.com | China | 87 | 58 |
| Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. | 13396369453 18678026865 | sdfantai@163.com | China | 904 | 58 |
| Shandong Xinlonghui Chemical Import and Export Co., Ltd. | 15866633566 | 395636713@qq.com | China | 74 | 58 |
| Jinan Leihe Trading Co., Ltd | 0531-88773819 13305412878 | 849314057@qq.com | China | 108 | 58 |
| Hubei Qifei Pharmaceutical Chemical Co., Ltd | 027-59322506 18071128681 | 1438082200@qq.com | China | 9554 | 58 |
| FoShan BeiSi Chemical Co., Ltd. | 19584229548 15218144393 | 3418849028@qq.com | China | 1116 | 58 |
| Shandong Mingyao Chemical Co., Ltd. | 13287741688 | 1726061144@qq.com | China | 154 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
View Latest Price from N-Methylolacrylamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | N-Methylolacrylamide
924-42-5
|
$2.00-6.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-06-30 | N-Methylolacrylamide
924-42-5
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-05-28 | N-Methylolacrylamide
924-42-5
|
$1.00 | 10kg | 99 % | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- N-Methylolacrylamide
924-42-5
- $2.00-6.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- N-Methylolacrylamide
924-42-5
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- N-Methylolacrylamide
924-42-5
- $1.00
- 99 %
- Hebei Chuanghai Biotechnology Co,.LTD
924-42-5 (N-Methylolacrylamide ) Related Search:
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N-(HYDROXYMETHYL)ACRYLAMIDE
N-Methanolacrylamide
N-Methylolacrylamide (NMA)
924-42-5
942-42-5
2473-57-4
C4H7O2N
CH2CHCONHCH2OH
H2CCCH3CONHOH
AMINE
fine chemicals
Acrylamide and Methacrylamide
Acrylic Monomers
Monomers
924-42-5
