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ChemicalBook >> CAS DataBase List >>2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine

2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine

2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine Structure
2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine structure
CAS No.
74901-69-2
Chemical Name:
2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine
Synonyms
7-dihydrothieno[3;tert-butyl 3-BroMo-6;2,4-Dichloro-6,7-dihydro-thieno[3,2-;2,4-dichloro-6H,7H-thieno[3,2-d]pyrimidine;2,4-Dichloro-6,7-dihyrothieno[3,2-d]pyrimidine;2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine;2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidi...;Thieno[3,2-d]pyrimidine, 2,4-dichloro-6,7-dihydro-;2, 4-dichloro-6, 7-dihydrothiophene [3, 2-d] pyrimidine;2,4-Dichloro-6,7-dihydrothieno[3,2-D]pyrimidine 5,5-dioxide
CBNumber:
CB31856090
Molecular Formula:
C6H4Cl2N2S
Molecular Weight:
207.08
MDL Number:
MFCD11109461
MOL File:
74901-69-2.mol
Last updated:2025-07-24 18:13:54
Product description Number Pack Size Price
2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine D435538 50mg $45
2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine D435538 100mg $60
2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine FD142208 250mg $80
2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine FD142208 500mg $135
2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine FD142208 1g $237.5
More product size
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2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine Properties

Boiling point 329.4±42.0 °C(Predicted)
Density 1.613±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka -2.53±0.20(Predicted)
Appearance Off-white to light yellow Solid
InChI InChI=1S/C6H4Cl2N2S/c7-5-4-3(1-2-11-4)9-6(8)10-5/h1-2H2
InChIKey CUVQFHMQHBMFCI-UHFFFAOYSA-N
SMILES C1(Cl)=NC(Cl)=C2SCCC2=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26

2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D435538 2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine 74901-69-2 50mg $45 2021-12-16 Buy
TRC D435538 2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine 74901-69-2 100mg $60 2021-12-16 Buy
Biosynth Carbosynth FD142208 2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine 74901-69-2 250mg $80 2021-12-16 Buy
Biosynth Carbosynth FD142208 2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine 74901-69-2 500mg $135 2021-12-16 Buy
Biosynth Carbosynth FD142208 2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine 74901-69-2 1g $237.5 2021-12-16 Buy
Product number Packaging Price Buy
D435538 50mg $45 Buy
D435538 100mg $60 Buy
FD142208 250mg $80 Buy
FD142208 500mg $135 Buy
FD142208 1g $237.5 Buy

2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine Chemical Properties,Uses,Production

Synthesis

6,7-dihydrothieno[3,2-d]pyrimidine-2,4-diol

913581-92-7

2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine

74901-69-2

General procedure for the synthesis of 2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine (VII) from 6,7-dihydrothieno[3,2-d]pyrimidine-2,4-diol (VI): 2.4 g (14.1 mmol) of 6,7-dihydrothieno[3,2-d]pyrimidine-2,4-diol (VI) was suspended in 14 mL of phosphorus oxychloride and added with 4.5 mL (28.2 mmol) of diethylaniline and the mixture was stirred at 80 °C for 22 hours. Upon completion of the reaction, it was cooled to room temperature and the reaction mixture was slowly poured into ice water, the precipitate formed was collected by filtration and washed with cold water. The resulting precipitate was dissolved in dichloromethane and the water was removed by a phase separator. The organic phase was concentrated to dryness under reduced pressure to give 2.5 g of the target product VII in 85% yield.

References

[1] Organic Process Research and Development, 2016, vol. 20, # 5, p. 982 - 988
[2] Patent: WO2006/111549, 2006, A1. Location in patent: Page/Page column 61; 59; 65; 68; 69; 72; 74; 76; 84
[3] Patent: US2007/259846, 2007, A1. Location in patent: Page/Page column 30; 31
[4] Patent: WO2013/26797, 2013, A1. Location in patent: Page/Page column 24-25
[5] Patent: US2013/150341, 2013, A1. Location in patent: Paragraph 0364; 0365; 0366; 0367

2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine Preparation Products And Raw materials

Raw materials

6,7-dihydrothieno[3,2-d]pyrimidine-2,4-diol

Preparation Products

2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine Suppliers

Global( 133)Suppliers
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Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29850 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 8026 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15131 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Accela ChemBio Inc. 		58
Hubei xin bonus chemical co. LTD 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
ANHUI WITOP BIOTECH CO., LTD 		58
Shaanxi Dideu Medichem Co. Ltd 		58
AFINE CHEMICALS LIMITED 		58

View Lastest Price from 2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine pictures 2025-06-25 2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine
74901-69-2
 US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine pictures 2019-07-06 2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine
74901-69-2
US $40.00-1500.00 / KG 1G 98% 100kg Career Henan Chemical Co

2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine Spectrum

2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine(74901-69-2)1HNMR

74901-69-2(2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine)Related Search:

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5-ACETYL-3,4-DIMETHYLTHIENO[2,3-B]THIOPHENE-2-CARBONITRILE 2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine

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2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine 2,4-Dichloro-6,7-dihyrothieno[3,2-d]pyrimidine 7-dihydrothieno[3 tert-butyl 3-BroMo-6 2,4-Dichloro-6,7-dihydro-thieno[3,2- 2,4-dichloro-6H,7H-thieno[3,2-d]pyrimidine 2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidi... Thieno[3,2-d]pyrimidine, 2,4-dichloro-6,7-dihydro- 2,4-Dichloro-6,7-dihydrothieno[3,2-D]pyrimidine 5,5-dioxide FAVORITES COMPARE 2,4-DICHLORO-6,7-DIHYDROTHIENO[3,2-D]PYRIMIDINE 74901-69-2 2,4-dichloro-6,7-dihydrothieno[3,2-d]pyrimidine ISO 9001：2015 REACH 2, 4-dichloro-6, 7-dihydrothiophene [3, 2-d] pyrimidine 74901-69-2 Heterocycle-Pyrimidine series CHIRAL CHEMICALS