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ChemicalBook >> CAS DataBase List >>(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone

(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone

(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone Structure
(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone structure
CAS No.
23027-91-0
Chemical Name:
(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone
Synonyms
Physalin A;(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone;1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,8aH)-tetrone, 2,3,6,6a,9,10,10a,10b,14,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,6a,10b-trimethyl-3-methylene-, (1S,2S,6R,6aS,8aR,10aS,10bR,16R,16aS,17R,18aR)-
CBNumber:
CB32174403
Molecular Formula:
C28H30O10
Molecular Weight:
526.53
MDL Number:
MOL File:
23027-91-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Request For Quotation

(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone Properties

Boiling point 838.3±65.0 °C(Predicted)
Density 1.55±0.1 g/cm3(Predicted)
pka 9.82±0.70(Predicted)
form Solid
color White to off-white
InChIKey VELDODQHYQSJOF-RKWIMMEGSA-N

(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 583052 Physalin A ≥98% 23027-91-0 5mg $585 2026-06-03 Buy
ChemScene CS-0226282 Physalin A 99.63% 23027-91-0 1mg $390 2026-06-04 Buy
ChemScene CS-0226282 Physalin A 99.63% 23027-91-0 5mg $997 2026-06-04 Buy
ChemScene CS-0226282 Physalin A 99.63% 23027-91-0 10mg $1603 2026-06-04 Buy
Biorbyt Ltd orb1681906 Physalin A 99.71% 23027-91-0 1mg $340 2026-05-06 Buy
Product number Packaging Price Buy
583052 5mg $585 Buy
CS-0226282 1mg $390 Buy
CS-0226282 5mg $997 Buy
CS-0226282 10mg $1603 Buy
orb1681906 1mg $340 Buy

(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone Chemical Properties, Uses, Production

Uses

Physalin A is a bioactive withanolide which induces apoptosis via p-53-Noxa-mediated ROS generation.

in vivo

Physalin A (40-80 mg/kg; Intraperitoneal injection; 10 days) has antitumor effect in H292 xenograft tumor model[3].
Physalin A (2 μL 20 μM; Injection of nucleus pulposus of the disc; Single dose) has a protective effect in a rat model of disc degeneration[4].

Animal Model:Male BALB/c mice[3]
Dosage:40 and 80 mg/kg
Administration:Intraperitoneal injection (i.p.); 10 days
Result:Significantly reduced the mean tumor volume and tumor weight, had the least effect on the weight of mice.
Decreased Tyr705-p-STAT3 levels, and increased caspase-3 activation.
Animal Model:Male Sprague-Dawley rats aged 6-8 weeks old (220±20 g) with intervertebral disc degeneration[4]
Dosage:2 μL 20 μM
Administration:Injection of nucleus pulposus of the disc; Single dose
Result:Alleviated disc degradation.
Reduced inflammation and fibrosis.

(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone Preparation Products And Raw materials

Raw materials

Preparation Products

(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone Suppliers

Global Suppliers ( 31)
Supplier Tel Email Country ProdList Advantage
Chengdu Bioanseis Phytochemicals Co., Ltd. 13518187787 632977132@qq.com China 315 58
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Chengdu Push Bio-Technology Co., Ltd. 028-85370565-229 18080489829 18080489829@163.com China 8379 60
Shanghai Standard Technology Co.,Ltd. 021-021-57127007-6622-6622 17621252073 luzh@nature-standard.com China 3021 58
Nanjing Digger Medical Technology Co. Ltd. 025-025-51191215 18013836722 2399235533@qq.com China 4932 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shandong WorldSun Biological Technology Co., Ltd. 0531-88723173 18596073690 1047208234@qq.com China 8174 58
Shanghai Hewu Biotechnology Co., LTD 021-57886085 17317861055 shhebio@126.com CHINA 7971 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Supplier Advantage
Chengdu Bioanseis Phytochemicals Co., Ltd. 58
Wuhan ChemFaces Biochemical Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Chengdu Push Bio-Technology Co., Ltd. 60
Shanghai Standard Technology Co.,Ltd. 58
Nanjing Digger Medical Technology Co. Ltd. 58
TargetMol Chemicals Inc. 58
Shandong WorldSun Biological Technology Co., Ltd. 58
Shanghai Hewu Biotechnology Co., LTD 58
Energy Chemical 58

View Latest Price from (16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Physalin A pictures 2026-07-27 Physalin A
23027-91-0
 $297.00-1220.00 99.71% 10g TargetMol Chemicals Inc.
  • Physalin A pictures
  • Physalin A
    23027-91-0
  • $297.00-1220.00
  • 99.71%
  • TargetMol Chemicals Inc.

(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone Spectrum

(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone(23027-91-0)1HNMR

23027-91-0 ((16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone) Related Search:

(16β,22R)-14α,17-Epoxy-13,14,20,22-tetrahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone physalin F Physalin G physalin B (13S,14R,22R,25S)-1,15-Dioxo-5-chloro-6β,13,20,22-tetrahydroxy-14,17α:14,27-diepoxy-16β,24-cyclo-13,14-seco-5α-ergosta-2-ene-18,26-dioic acid 18,20:26,22-dilactone
1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,8aH)-tetrone, 2,3,6,6a,9,10,10a,10b,14,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,3,6a,10b-tetramethyl-, (1S,2S,3S,6R,6aS,8aR,10aS,10bR,16R,16aS,17R,18aR)- PHYSALIN D

1of2

(16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone 1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,8aH)-tetrone, 2,3,6,6a,9,10,10a,10b,14,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,6a,10b-trimethyl-3-methylene-, (1S,2S,6R,6aS,8aR,10aS,10bR,16R,16aS,17R,18aR)- Physalin A 23027-91-0