GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA
- CAS No.
- 99026-77-4
- Chemical Name:
- GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA
- Synonyms
- GKGAGLSLSRFSWGA;[ALA107]-MBP (104-118);[ALA107]-MBP FRAGMENT 104-118;[Ala107]-MBP (104-118) acetate Salt;[Ala107]-Myelin Basic Protein (104-118);[ALA107]-MYELIN BASIC PROTEIN FRAGMENT 104-118;[Ala107]-Myelin Basic Protein Fragment 104-118;GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA;L-Alanine, glycyl-L-lysylglycyl-L-alanylglycyl-L-leucyl-L-seryl-L-leucyl-L-seryl-L-arginyl-L-phenylalanyl-L-seryl-L-tryptophylglycyl- (9CI);(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[(2S)-6-amino-2-[(2-aminoacetyl)amino]hexanoyl]amino]acetyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]acetyl]amino]propanoic acid
- CBNumber:
- CB3236444
- Molecular Formula:
- C67H104N20O19
- Molecular Weight:
- 1493.67
- MDL Number:
- MFCD00273540
- MOL File:
- 99026-77-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| [Ala107]-MBP(104-118) | 1900 | 1 | $137 |
| [Ala107]-MBP(104-118) | B5218 | 1mg | $308 |
| [ALA107]-MYELIN BASIC PROTEIN (104-118) 95.00% | KIN0000844 | 1MG | $697.34 |
| [ALA107]-MYELIN BASIC PROTEIN (104-118) 95.00% | KIN0000844 | 5MG | $1206.98 |
| storage temp. | −20°C |
|---|---|
| solubility | Soluble to 1 mg/ml in 10% acetonitrile |
| form | solid |
| color | White |
| biological source | human |
| Sequence | H-Gly-Lys-Gly-Ala-Gly-Leu-Ser-Leu-Ser-Arg-Phe-Ser-Trp-Gly-Ala-OH |
| InChIKey | PKKMMDDHSZRJTF-NBRSAOMZSA-N |
| UNSPSC Code | 12352200 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 1900 | [Ala107]-MBP(104-118) | 99026-77-4 | 1 | $137 | 2021-12-16 | Buy |
| ApexBio Technology | B5218 | [Ala107]-MBP(104-118) | 99026-77-4 | 1mg | $308 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000844 | [ALA107]-MYELIN BASIC PROTEIN (104-118) 95.00% | 99026-77-4 | 1MG | $697.34 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000844 | [ALA107]-MYELIN BASIC PROTEIN (104-118) 95.00% | 99026-77-4 | 5MG | $1206.98 | 2021-12-16 | Buy |
GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA Chemical Properties,Uses,Production
Uses
[Ala107]MBP(104-118) is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 46-145 μM[1].
Biological Activity
[ala107]-mbp (104-118) is a non-competitive inhibitor of pkc and synthetic peptide analog of bovine myelin basic protein (mbp) with ic50 value of 46 - 145 mm.1. substrate specificity of phospholipid/ca2+ dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein. turner et al. j.biol.chem., 1985;260:115032. synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase c). su et al. biochem.biophys.res.commun., 1986;134:78
Biochem/physiol Actions
[Ala107]-Myelin Basic Protein Fragment 104-118 is an inhibitor of protein kinase C.
IC 50
PKC: 46-145 μM (IC50)
References
[1] Su HD, et, al. Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C). Biochem Biophys Res Commun. 1986 Jan 14; 134(1): 78-84. DOI:10.1016/0006-291x(86)90529-2
GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA Preparation Products And Raw materials
Raw materials
Preparation Products
GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
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| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
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| Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5218 | 58 |
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| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13913916777 | info@chemlin.com.cn | China | 16027 | 64 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |




