ChemicalBook >> CAS DataBase List >>(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one structure

CAS No.: 957-66-4

Chemical Name:: (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one

Synonyms: Isolinderalactone;Reaxys ID: 5276986;3,4-b']difuran-2(3H)-one;Isolinderalactone, 10 mM in DMSO;(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b;(3aS)-4β-Vinyl-3a,4,5,8bβ-tetrahydro-4,8-dimethyl-3-methylenebenzo[1,2-b:3,4-b']difuran-2(3H)-one;(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b]difuran-2(3H)-one;(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one;(3aS,4R,8bR)-4,8-Dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one;Benzo[1,2-b:3,4-b']difuran-2(3H)-one, 4-ethenyl-3a,4,5,8b-tetrahydro-4,8-dimethyl-3-methylene-, (3aS,4R,8bR)-

CBNumber:: CB32424359

Molecular Formula:: C15H16O3

Molecular Weight:: 244.29

MDL Number:

MOL File:: 957-66-4.mol

MSDS File:: SDS

Last updated:2025-04-18 09:52:04

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(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Properties

Melting point	118-121℃
Boiling point	378.8±42.0 °C(Predicted)
Density	1.16±0.1 g/cm3 (20 ºC 760 Torr)
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
color	White to off-white

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	300486	Isolinderalactone	957-66-4	20mg	$509	2021-12-16	Buy
AvaChem	4262	Isolinderalactone	957-66-4	20mg	$690	2021-12-16	Buy
AvaChem	4262	Isolinderalactone	957-66-4	1mg	$119	2021-12-16	Buy
Arctom	CFN99762	Isolinderalactone	957-66-4	5mg	$238	2021-12-16	Buy
DC Chemicals	DCZ-124	Isolinderalactone >98%	957-66-4	20mg	$280	2021-12-16	Buy

Product number	Packaging	Price	Buy
300486	20mg	$509	Buy
4262	20mg	$690	Buy
4262	1mg	$119	Buy
CFN99762	5mg	$238	Buy
DCZ-124	20mg	$280	Buy

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Chemical Properties,Uses,Production

Uses

Isolinderalactone suppresses human glioblastoma growth and angiogenic activity through the inhibition of VEGFR2 activation in endothelial cells[1]. Isolinderalactone suppresses the expression of B-cell lymphoma 2 (Bcl-2), survi

Definition

ChEBI: Isolinderalactone is a member of benzofurans. It has a role as a metabolite.

IC 50

VEGFR2; Bcl-2

References

[1] Park JH, et al. Isolinderalactone suppresses human glioblastoma growth and angiogenic activity in 3D microfluidic chip and in vivo mouse models.?Cancer Lett. 2020;478:71-81. DOI:10.1016/j.canlet.2020.03.009
[2] Hwang JY, et al. Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model.?Cancer Lett. 2019;443:25-33. DOI:10.1016/j.canlet.2018.11.027

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Suppliers

Global( 69)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	3772	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32268	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10244	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38663	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
Chemwill Asia Co.,Ltd.	86-21-51086038	chemwill_asia@126.com	CHINA	23912	58

Supplier	Advantage
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Shanghai Standard Technology Co., Ltd.	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58
Chemwill Asia Co.,Ltd.	58

View Lastest Price from (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-05-02	Isolinderalactone 957-66-4	US $71.00-286.00 / mg		99.62%	10g	TargetMol Chemicals Inc.
	2023-02-24	Isolinderalactone 957-66-4	US $0.00 / mg	20mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.

Isolinderalactone
957-66-4
US $71.00-286.00 / mg
99.62%
TargetMol Chemicals Inc.

Isolinderalactone
957-66-4
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Spectrum

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one(957-66-4)¹HNMR (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one(957-66-4)¹³CNMR

957-66-4((3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one)Related Search:

3-Methyl-1-butanol Polycaprolactone

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one (3aS)-4β-Vinyl-3a,4,5,8bβ-tetrahydro-4,8-dimethyl-3-methylenebenzo[1,2-b:3,4-b']difuran-2(3H)-one (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b 3,4-b']difuran-2(3H)-one Isolinderalactone Reaxys ID: 5276986 Benzo[1,2-b:3,4-b']difuran-2(3H)-one, 4-ethenyl-3a,4,5,8b-tetrahydro-4,8-dimethyl-3-methylene-, (3aS,4R,8bR)- (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b]difuran-2(3H)-one (3aS,4R,8bR)-4,8-Dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Survivin,VEGFR,Isolinderalactone,Vascular endothelial growth factor receptor,Inhibitor,IAP,Bcl-2 Family,inhibit (3aS,4R,8bR)-4,8-Dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one , Isolinderalactone Isolinderalactone, 10 mM in DMSO 957-66-4 Sesquiterpenoids