ChemicalBook >> CAS DataBase List >>(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one structure

CAS No.: 957-66-4

Chemical Name:: (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one

Synonyms: Isolinderalactone;Reaxys ID: 5276986;3,4-b']difuran-2(3H)-one;Isolinderalactone, 10 mM in DMSO;(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b;(3aS)-4β-Vinyl-3a,4,5,8bβ-tetrahydro-4,8-dimethyl-3-methylenebenzo[1,2-b:3,4-b']difuran-2(3H)-one;(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b]difuran-2(3H)-one;(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one;(3aS,4R,8bR)-4,8-Dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one;Benzo[1,2-b:3,4-b']difuran-2(3H)-one, 4-ethenyl-3a,4,5,8b-tetrahydro-4,8-dimethyl-3-methylene-, (3aS,4R,8bR)-

CBNumber:: CB32424359

Molecular Formula:: C15H16O3

Molecular Weight:: 244.29

MDL Number:

MOL File:: 957-66-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-27 17:00:41

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(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Properties

Melting point	118-121℃
Boiling point	378.8±42.0 °C(Predicted)
Density	1.16±0.1 g/cm3 (20 ºC 760 Torr)
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
color	White to off-white

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	AAA95766	Isolinderalactone	957-66-4	25mg	$1205.5	2026-06-04	Buy
Biosynth	AAA95766	Isolinderalactone	957-66-4	50mg	$1677.5	2026-06-04	Buy
Biosynth	AAA95766	Isolinderalactone	957-66-4	100mg	$2685	2026-06-04	Buy
ChemScene	CS-0022898	Isolinderalactone 98.79%	957-66-4	5mg	$217	2026-06-04	Buy
ChemScene	CS-0022898	Isolinderalactone 98.79%	957-66-4	10mg	$357	2026-06-04	Buy

Product number	Packaging	Price	Buy
AAA95766	25mg	$1205.5	Buy
AAA95766	50mg	$1677.5	Buy
AAA95766	100mg	$2685	Buy
CS-0022898	5mg	$217	Buy
CS-0022898	10mg	$357	Buy

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Chemical Properties, Uses, Production

Chemical Properties

Off-white needle-like crystals, soluble in methanol, ethanol, DMSO and other organic solvents, from Camphoraceae (Lauraceae) Uva Ursi Lindera strychnifolia Vill. root fine trace Neolitsea aciculata Koidz. root, trunk NANRENSHAN NEW WOOD JIANG ZI Neolitsea Roots of Neolitsea villosa (Blume) Merr.

Uses

Isolinderalactone suppresses human glioblastoma growth and angiogenic activity through the inhibition of VEGFR2 activation in endothelial cells[1]. Isolinderalactone suppresses the expression of B-cell lymphoma 2 (Bcl-2), survi

Definition

ChEBI: Isolinderalactone is a member of benzofurans. It has a role as a metabolite.

IC 50

VEGFR2; Bcl-2

References

[1] Park JH, et al. Isolinderalactone suppresses human glioblastoma growth and angiogenic activity in 3D microfluidic chip and in vivo mouse models.Cancer Lett. 2020;478:71-81. DOI:10.1016/j.canlet.2020.03.009
[2] Hwang JY, et al. Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model.Cancer Lett. 2019;443:25-33. DOI:10.1016/j.canlet.2018.11.027

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Suppliers

Global Suppliers ( 86)

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu Biopurify Phytochemicals Ltd.	+86-028-82633397 18982077548	cwb1@biopurify.cn	China	2376	60
Shanghai Tauto Biotech Co., Ltd.	021-51320588	tauto@tautobiotech.com	China	3984	66
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2774	58
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58
AdooQ Bioscience CHINA	025-58849295	info@adooq.cn	China	2981	60
Wuhan ChemFaces Biochemical Co., Ltd.	18607101326 15172504745	aileen@chemfaces.com	China	6904	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Shanghai Uteam Biotechnology Co., Ltd.	021-36031160 13311776681	3338195766@QQ.com	China	5091	55
Shanghai Biological Technology Development Co., Ltd.	021-69955236-807 13918189704	chinaruji@chinaruji.com	China	5093	55

Supplier	Advantage
Chengdu Biopurify Phytochemicals Ltd.	60
Shanghai Tauto Biotech Co., Ltd.	66
AdooQ BioScience, LLC	58
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
AdooQ Bioscience CHINA	60
Wuhan ChemFaces Biochemical Co., Ltd.	55
EMMX Biotechnology LLC	60
Shanghai YuanYe Biotechnology Co., Ltd.	60
Shanghai Uteam Biotechnology Co., Ltd.	55
Shanghai Biological Technology Development Co., Ltd.	55

View Latest Price from (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-27	Isolinderalactone 957-66-4	$67.00-272.00		98.76%	10g	TargetMol Chemicals Inc.
	2023-02-24	Isolinderalactone 957-66-4		20mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.

Isolinderalactone
957-66-4
$67.00-272.00
98.76%
TargetMol Chemicals Inc.

Isolinderalactone
957-66-4
$0.00
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Spectrum

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one(957-66-4)¹HNMR (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one(957-66-4)¹³CNMR

957-66-4 ((3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one) Related Search:

Polycaprolactone 3-Methyl-1-butanol (R,10E)-4,8,9,12-Tetrahydro-3,11-dimethyl-6H-4,7-methenofuro[3,2-c]oxacycloundecin-6-one Dasycarpol Naphtho[2,3-b]furan-6-ol, 4,4a,5,6,7,8,8a,9-octahydro-3,8a-dimethyl-5-methylene-, 6-acetate, (4aR,6S,8aR)-

Linderene acetate

1of2

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one (3aS)-4β-Vinyl-3a,4,5,8bβ-tetrahydro-4,8-dimethyl-3-methylenebenzo[1,2-b:3,4-b']difuran-2(3H)-one (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b 3,4-b']difuran-2(3H)-one Reaxys ID: 5276986 Benzo[1,2-b:3,4-b']difuran-2(3H)-one, 4-ethenyl-3a,4,5,8b-tetrahydro-4,8-dimethyl-3-methylene-, (3aS,4R,8bR)- (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b]difuran-2(3H)-one (3aS,4R,8bR)-4,8-Dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one Survivin,VEGFR,Isolinderalactone,Vascular endothelial growth factor receptor,Inhibitor,IAP,Bcl-2 Family,inhibit (3aS,4R,8bR)-4,8-Dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one , Isolinderalactone Isolinderalactone, 10 mM in DMSO Isolinderalactone 957-66-4 Sesquiterpenoids