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(+/-)-LY367385

(+/-)-LY367385 Structure
(+/-)-LY367385 structure
CAS No.
198419-90-8
Chemical Name:
(+/-)-LY367385
Synonyms
(+/-)-LY367385;LY 367385, (±)-;4-(AMINO-CARBOXY-METHYL)-3-METHYL-BENZOIC ACID;Benzeneacetic acid, α-amino-4-carboxy-2-methyl-;BENZENEACETIC ACID, A-AMINO-4-CARBOXY-2-METHYL-
CBNumber:
CB32454095
Molecular Formula:
C10H11NO4
Molecular Weight:
209.2
MDL Number:
MFCD10565942
MOL File:
198419-90-8.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24
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(+/-)-LY367385 Properties

Boiling point 434.0±45.0 °C(Predicted)
Density 1.393±0.06 g/cm3(Predicted)
solubility Water: 20 mg/ml
form A solid
pka 1.72±0.10(Predicted)
color White to off-white

(+/-)-LY367385 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 33158 (±)-LY367385 ≥98% 198419-90-8 1mg $69 2026-04-30 Buy
Cayman Chemical 33158 (±)-LY367385 ≥98% 198419-90-8 5mg $214 2026-04-30 Buy
Cayman Chemical 33158 (±)-LY367385 ≥98% 198419-90-8 10mg $393 2026-04-30 Buy
Cayman Chemical 33158 (±)-LY367385 ≥98% 198419-90-8 25mg $901 2026-04-30 Buy
ChemScene CS-0112978 (±)-LY367385 98.0% 198419-90-8 1mg $76 2026-06-04 Buy
Product number Packaging Price Buy
33158 1mg $69 Buy
33158 5mg $214 Buy
33158 10mg $393 Buy
33158 25mg $901 Buy
CS-0112978 1mg $76 Buy

(+/-)-LY367385 Chemical Properties,Uses,Production

Description

(±)-LY367385 is an antagonist of metabotropic glutamate receptor 1α (mGluR1α).1 It inhibits phosphoinositide (PI) hydrolysis selectively in AV-12 cells expressing mGluR1α over those expressing mGluR5a (IC50s = 19 and >300 μM, respectively).

Uses

(±)-LY367385 is the racemate of LY367385. LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis，compared with > 100 μM for mGlu5a[1][2].

References

1. Salt, T.E., Jones, H.E., Copeland, C.S., et al. Function of mGlu1 receptors in the modulation of nociceptive processing in the thalamus Neuropharmacology 79(100),405-411(2014).

(+/-)-LY367385 Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)-LY367385 Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
BOC Sciences +1-631-485-4226 inquiry@bocsci.com United States 19935 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
ChemeGen 18818260767 2625930290@qq.com China 6966 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1246 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
BOC Sciences 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
ChemeGen 58
Beijing Biocreative Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58

198419-90-8((+/-)-LY367385)Related Search:

(+/-)-LY367385 LY 367385 AIDA (1S)-1-Amino-1,2,3,4-tetrahydronaphthalene-1,6-dicarboxylic acid (1R)-1-Amino-1,2,3,4-tetrahydronaphthalene-1,6-dicarboxylic acid
ATENOLOL-D7

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4-(AMINO-CARBOXY-METHYL)-3-METHYL-BENZOIC ACID BENZENEACETIC ACID, A-AMINO-4-CARBOXY-2-METHYL- LY 367385, (±)- Benzeneacetic acid, α-amino-4-carboxy-2-methyl- (+/-)-LY367385 198419-90-8