Benzoic acid, 5-methoxy-2-methyl-, ethyl ester
- CAS No.
- 855949-35-8
- Chemical Name:
- Benzoic acid, 5-methoxy-2-methyl-, ethyl ester
- Synonyms
- ethyl 5-Methoxy-2-Methylbenzoate;Benzoic acid, 5-methoxy-2-methyl-, ethyl ester
- CBNumber:
- CB32459010
- Molecular Formula:
- C11H14O3
- Molecular Weight:
- 194.23
- MDL Number:
- MFCD11226201
- MOL File:
- 855949-35-8.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
Benzoic acid, 5-methoxy-2-methyl-, ethyl ester price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS110706 | Ethyl 5-methoxy-2-methylbenzoate 97% | 855949-35-8 | 5g | $34 | 2026-06-04 | Buy |
| Activate Scientific | AS110706 | Ethyl 5-methoxy-2-methylbenzoate 97% | 855949-35-8 | 25g | $106 | 2026-06-04 | Buy |
| Activate Scientific | AS110706 | Ethyl 5-methoxy-2-methylbenzoate 97% | 855949-35-8 | 100g | $307 | 2026-06-04 | Buy |
| aablocks | AA00G5J0 | Ethyl 5-methoxy-2-methylbenzoate 99+% | 855949-35-8 | 1g | $8 | 2026-05-28 | Buy |
| aablocks | AA00G5J0 | Ethyl 5-methoxy-2-methylbenzoate 99+% | 855949-35-8 | 5g | $16 | 2026-05-28 | Buy |
Benzoic acid, 5-methoxy-2-methyl-, ethyl ester Chemical Properties, Uses, Production
Synthesis
34265-55-9
74-88-4
855949-35-8
Step D: Synthesis of ethyl 5-methoxy-2-methylbenzoate as an intermediate; sodium hydride (60% dispersed in mineral oil, 1.50 g, 37.4 mmol) was suspended in N,N-dimethylformamide (50 mL) under nitrogen protection and stirred for 10 min. Subsequently, a solution of ethyl 5-hydroxy-2-methylbenzoate (5.18 g, 28.7 mmol) in N,N-dimethylformamide (100 mL) was slowly added dropwise. After the dropwise addition was completed, stirring of the reaction mixture was continued for 3 hours at room temperature. Next, iodomethane (2.69 mL, 43.1 mmol) was added and the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was poured into water (200 mL) and extracted with ethyl acetate (200 mL). The organic phase was washed sequentially with 5% aqueous lithium chloride (200 mL), water (200 mL) and brine (100 mL), dried over anhydrous magnesium sulfate and concentrated under reduced pressure. Purification by fast column chromatography (silica gel, ethyl acetate/hexane=1:19) afforded ethyl 5-methoxy-2-methylbenzoate (4.18 g, 75% yield) as a colorless oily liquid.1H NMR (300 MHz, CDCl3) δ 7.44 (d, J=2.7 Hz, 1H), 7.14 (d, J=8.4 Hz, 1H), 6.95 ( dd, J=2.7,8.4Hz, 1H), 4.35 (q, J=7.2Hz, 2H), 3.82 (s, 3H), 2.51 (s, 3H), 1.39 (t, J=7.2Hz, 3H).
References
[1] Patent: WO2009/42907, 2009, A1. Location in patent: Page/Page column 35
Benzoic acid, 5-methoxy-2-methyl-, ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Benzoic acid, 5-methoxy-2-methyl-, ethyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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