1H-Indene-2-boronic acid pinacol ester
- CAS No.
- 749869-98-5
- Chemical Name:
- 1H-Indene-2-boronic acid pinacol ester
- Synonyms
- 1H-Indene-2-boronic acid picol ester;1H-Indene-2-boronic acid pinacol ester;1H-Indene-2-boronic acid pinacol ester 97%;1H-Indene-2-boronic acid pinacol ester;2-(1H-Inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;1,3,2-Dioxaborolane, 2-(1H-inden-2-yl)-4,4,5,5-tetramethyl-
- CBNumber:
- CB32459409
- Molecular Formula:
- C15H19BO2
- Molecular Weight:
- 242.12
- MDL Number:
- MFCD11506072
- MOL File:
- 749869-98-5.mol
- MSDS File:
- SDS
| Melting point | 72-80°C |
|---|---|
| Boiling point | 293.4±50.0 °C(Predicted) |
| Density | 1.06±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | solid |
| Appearance | White to off-white Solid |
| InChI | 1S/C15H19BO2/c1-14(2)15(3,4)18-16(17-14)13-9-11-7-5-6-8-12(11)10-13/h5-9H,10H2,1-4H3 |
| InChIKey | GHLNFPJNICWOHP-UHFFFAOYSA-N |
| SMILES | CC1(C)OB(OC1(C)C)C2=Cc3ccccc3C2 |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
1H-Indene-2-boronic acid pinacol ester price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 766070 | 1H-Indene-2-boronic acid pinacol ester 97% | 749869-98-5 | 500mg | $307 | 2026-04-30 | Buy |
| Biosynth | ZEB86998 | 1H-Indene-2-boronic acid pinacol ester | 749869-98-5 | 1g | $306.8 | 2026-06-05 | Buy |
| Biosynth | ZEB86998 | 1H-Indene-2-boronic acid pinacol ester | 749869-98-5 | 10g | $1652 | 2026-06-05 | Buy |
| Ambeed | A342414 | 2-(1H-Inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95% | 749869-98-5 | 100mg | $27 | 2026-06-05 | Buy |
| Ambeed | A342414 | 2-(1H-Inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95% | 749869-98-5 | 250mg | $51 | 2026-06-05 | Buy |
1H-Indene-2-boronic acid pinacol ester Chemical Properties, Uses, Production
Synthesis
10485-09-3
25015-63-8
749869-98-5
The general procedure for the synthesis of 2-(1H-inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolanes from 2-bromoindene and pinacolborane was carried out as follows: under nitrogen protection (PPh3)2PdCl2 (0.54 g, 0.77 mmol) and 2-bromoindene (4.98 g, 25.54 mmol) were added to a pre-oven-dried Schlenk flask followed by addition of dioxane (50 mL). Triethylamine (10.7 mL, 76.6 mmol) and pinacolborane (5.56 mL, 38.31 mmol) were added sequentially via syringe at room temperature (25 °C). The reaction mixture was stirred at 80 °C for 5.5 hours. After completion of the reaction, it was cooled to room temperature, the reaction was quenched with water and saturated saline (20 mL) was added. The organic layer was separated and the aqueous layer was extracted with ether (2 x 50 mL). The organic layers were combined, washed with brine, dried over anhydrous Na2SO4 and concentrated. Purification of the residue by Kugelrohr distillation gave the target product 2-(1H-inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane as a white solid (melting point 73-74 °C) in 69% yield. The product is stable in air and can be stored and handled.1H NMR (300 MHz, CDCl3) δ 7.58 (s, 1H), 7.50 (d, J = 7 Hz, 1H), 7.46 (d, J = 7 Hz, 1H), 7.30-7.21 (m, 2H), 3.54 (s, 2H), 1.33 (s, 12H); 13C NMR (75 MHz, CDCl3) δ 147.0, 145.7, 145.0, 126.3, 126.0, 124.0, 122.0, 83.6, 41.7, 25.1.
References
[1] Patent: WO2013/91837, 2013, A1. Location in patent: Page/Page column 20; 21
[2] Patent: WO2013/91836, 2013, A1. Location in patent: Page/Page column 20; 21
1H-Indene-2-boronic acid pinacol ester Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Indene-2-boronic acid pinacol ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
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| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| JW & Y Pharmlab Co., Ltd. | 021-64340559 | xinyu_shi@jwypharmlab.com.cn | China | 11999 | 58 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Shanghai zhigan biotechnology co., LTD | zhiqianbio@126.com | China | 19765 | 58 | |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-025-85560043 17301488900 | info@synzest.com | China | 9274 | 58 |
| Zhengzhou Alpha Chemical Co. LTD | 0371-53732842 13383863444 | 3838551451@qq.com | China | 9997 | 58 |
