1-Acetyl-4-bocamino-piperidine
- CAS No.
- 283167-28-2
- Chemical Name:
- 1-Acetyl-4-bocamino-piperidine
- Synonyms
- 1-Acetyl-4-bocamino-piperidine;1-Acetyl-4-Boc-amino-piperidine, 97.5%;tert-butyl 1-acetylpiperidin-4-ylcarbamate;tert-butyl N-(1-acetyl-4-piperidyl)carbamate;tert-butyl N-(1-acetylpiperidin-4-yl)carbaMate;(1-Acetyl-4-piperidinyl)carbamic acid 1,1-dimethylethyl ester;Carbamic acid, N-(1-acetyl-4-piperidinyl)-, 1,1-dimethylethyl ester
- CBNumber:
- CB32466476
- Molecular Formula:
- C12H22N2O3
- Molecular Weight:
- 242.31
- MDL Number:
- MFCD11844779
- MOL File:
- 283167-28-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Risk Statements | 20/21/22 |
| Safety Statements | 23-24/25 |
| HS Code | 29333990 |
1-Acetyl-4-bocamino-piperidine price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | B56301 | tert-Butyl (1-acetylpiperidin-4-yl)carbamate 97% | 283167-28-2 | 250mg | $90 | 2026-05-06 | Buy |
| Synthonix | B56301 | tert-Butyl (1-acetylpiperidin-4-yl)carbamate 97% | 283167-28-2 | 1g | $104 | 2026-05-06 | Buy |
| Synthonix | B56301 | tert-Butyl (1-acetylpiperidin-4-yl)carbamate 97% | 283167-28-2 | 5g | $187 | 2026-05-06 | Buy |
| Synthonix | B56301 | tert-Butyl (1-acetylpiperidin-4-yl)carbamate 97% | 283167-28-2 | 10g | $190 | 2026-05-06 | Buy |
| Synthonix | B56301 | tert-Butyl (1-acetylpiperidin-4-yl)carbamate 97% | 283167-28-2 | 25g | $270 | 2026-05-06 | Buy |
1-Acetyl-4-bocamino-piperidine Chemical Properties,Uses,Production
Synthesis
108-24-7
73874-95-0
283167-28-2
4-tert-butoxycarbonylaminopiperidine (5.0 g, 25 mmol) was dissolved in dichloromethane (80 mL) at 0 °C and triethylamine (3.8 g, 38 mmol) and acetic anhydride (2.6 g, 25 mmol) were added sequentially. The reaction mixture was stirred continuously at 0 °C for 2 hours. Upon completion of the reaction, the reaction was quenched by the addition of water (30 mL) and the organic phase was separated and washed with saturated sodium bicarbonate solution (30 mL). The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give tert-butyl (1-methylpiperidin-4-yl)carbamate (5.6 g, 93% yield) as a light yellow solid.LC-MS analysis: retention time 1.88 min; mass-to-charge ratio 265.1 [M+Na]+.
References
[1] Patent: WO2016/34673, 2016, A1. Location in patent: Page/Page column 91
[2] Patent: WO2016/34675, 2016, A1. Location in patent: Page/Page column 68
[3] Patent: WO2017/153520, 2017, A1. Location in patent: Page/Page column 64
[4] Patent: US2008/227780, 2008, A1. Location in patent: Page/Page column 53-54
[5] Patent: WO2015/198229, 2015, A1. Location in patent: Page/Page column 21
1-Acetyl-4-bocamino-piperidine Preparation Products And Raw materials
Raw materials
Preparation Products
1-Acetyl-4-bocamino-piperidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9336 | 55 |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9985 | 58 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
| Lanzhou HuaHao Pharmaceutical Co., Ltd. | 18189674620 | 761137152@qq.com | China | 490 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Dezhou LonWel Pharmaceutical Technology Co., Ltd. | 13761310616 | 39324283@qq.com | China | 1360 | 58 |
| Aikon International Limited | 025-66113011 19370895928 | qzhang@aikonchem.com | China | 15390 | 58 |
