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ChemicalBook >> CAS DataBase List >>(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone

(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone

(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone Structure
(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone structure
CAS No.
869490-23-3
Chemical Name:
(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone
Synonyms
Gosogliptin;PF-734200;PF-00734200;(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone;Methanone, (3,3-difluoro-1-pyrrolidinyl)[(2S,4S)-4-[4-(2-pyrimidinyl)-1-piperazinyl]-2-pyrrolidinyl]-
CBNumber:
CB32484726
Molecular Formula:
C17H24F2N6O
Molecular Weight:
366.41
MDL Number:
MOL File:
869490-23-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:04:24
Product description Number Pack Size Price
Gosogliptin ≥98% 33220 1mg $623
Gosogliptin 99.83% CS-6619 5mg $433
Gosogliptin 99.83% CS-6619 10mg $693
Gosogliptin 99.83% CS-6619 25mg $1452
Gosogliptin 99.83% CS-6619 50mg $2329
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(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone Properties

Boiling point 562.3±60.0 °C(Predicted)
Density 1.36
storage temp. Store at -20°C
solubility DMSO: soluble
form A solid
pka 8.95±0.10(Predicted)
color White to yellow
InChI InChI=1S/C17H24F2N6O/c18-17(19)2-5-25(12-17)15(26)14-10-13(11-22-14)23-6-8-24(9-7-23)16-20-3-1-4-21-16/h1,3-4,13-14,22H,2,5-12H2/t13-,14-/m0/s1
InChIKey QWEWGXUTRTXFRF-KBPBESRZSA-N
SMILES C(N1CCC(F)(F)C1)([C@@H]1C[C@H](N2CCN(C3=NC=CC=N3)CC2)CN1)=O
FDA UNII GI718UO477

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 33220 Gosogliptin ≥98% 869490-23-3 1mg $623 2026-04-30 Buy
ChemScene CS-6619 Gosogliptin 99.83% 869490-23-3 5mg $433 2026-06-04 Buy
ChemScene CS-6619 Gosogliptin 99.83% 869490-23-3 10mg $693 2026-06-04 Buy
ChemScene CS-6619 Gosogliptin 99.83% 869490-23-3 25mg $1452 2026-06-04 Buy
ChemScene CS-6619 Gosogliptin 99.83% 869490-23-3 50mg $2329 2026-06-04 Buy
Product number Packaging Price Buy
33220 1mg $623 Buy
CS-6619 5mg $433 Buy
CS-6619 10mg $693 Buy
CS-6619 25mg $1452 Buy
CS-6619 50mg $2329 Buy

(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone Chemical Properties,Uses,Production

Uses

Gosogliptin is used as a treatment for type 2 diabetes.

Definition

ChEBI: Gosogliptin is an amino acid amide.

in vivo

The objectives of the present study are to characterize the metabolism, pharmacokinetics, and excretion of [14C] Gosogliptin in Sprague-Dawley (SD) rats, beagle dogs, and humans. A single dose of [14C] Gosogliptin is administered orally to intact SD rats (5 mg/kg), beagle dogs (5 mg/kg), and humans (20 mg). After a single oral dose of [14C] Gosogliptin to SD rats, an overall mean of 97.1% of the administered radioactivity is recovered in the urine, feces, and cage wash over a period of 168 h postdose. The mean cumulative dose recovered in feces is 66.0%. The mean cumulative excretion in the urine is 30.8%. Approximately 95% of the excreted radioactivity recovery occurred in the first 48 h. Mean total recoveries of dosed radioactivity from bile duct-cannulated rats are 29.5% in urine and 62.0% in bile. No gender-related differences are observed in the excretion pattern of radioactivity[2].

IC 50

DPP-4

(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone Preparation Products And Raw materials

Raw materials

Preparation Products

(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone Suppliers

Global( 40)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21585 55
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39037 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19956 58
Shanghai Fine Biotech Co.，Ltd 18221172427; 18221172427 sale@fine-biotech.com China 225 58
Shanghai Zhuyan Biotechnology Co., Ltd. 17521259211 17521259211@163.com China 136 58
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 6002 61
Shanghai Fuhe Chemistry Technology Co., Ltd. 0086-21-67651709 cfx759@hotmail.com China 410 57
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Supplier Advantage
Henan Tianfu Chemical Co.,Ltd. 		55
CONIER CHEM AND PHARMA LIMITED 		58
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Shanghai Fine Biotech Co.，Ltd 58
Shanghai Zhuyan Biotechnology Co., Ltd. 58
Chembest Research Laboratories Limited 61
Shanghai Fuhe Chemistry Technology Co., Ltd. 57
BOC Sciences 65

View Lastest Price from (3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Gosogliptin pictures 2026-05-11 Gosogliptin
869490-23-3
 $1090.00-2380.00 99.74% 10g TargetMol Chemicals Inc.
Gosogliptin pictures 2025-05-13 Gosogliptin
869490-23-3
 $1160.00-2500.00 10g TargetMol Chemicals Inc.
  • Gosogliptin pictures
  • Gosogliptin
    869490-23-3
  • $1090.00-2380.00
  • 99.74%
  • TargetMol Chemicals Inc.
  • Gosogliptin pictures
  • Gosogliptin
    869490-23-3
  • $1160.00-2500.00
  • TargetMol Chemicals Inc.

(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone Spectrum

(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone(869490-23-3)1HNMR

869490-23-3((3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone)Related Search:

7-Amino-2-(pyrimidin-2-yl)-octahydropyrrolo[1,2-a]piperazin-6-one dihydrochloride (3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone
(3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone PF-00734200 PF-734200 Methanone, (3,3-difluoro-1-pyrrolidinyl)[(2S,4S)-4-[4-(2-pyrimidinyl)-1-piperazinyl]-2-pyrrolidinyl]- Gosogliptin 869490-23-3 C17H24F2N6O