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2-(pyridin-4-ylmethylamino)nicotinic acid

2-(pyridin-4-ylmethylamino)nicotinic acid Structure
2-(pyridin-4-ylmethylamino)nicotinic acid structure
CAS No.
854382-06-2
Chemical Name:
2-(pyridin-4-ylmethylamino)nicotinic acid
Synonyms
Nicotinamide Impurity 274;2-(pyridin-4-ylmethylamino)nicotinic acid;2-(4-pyridylmethylamino)pyridine-3-carboxylic acid;2-[(4-Pyridinylmethyl)amino]-3-pyridinecarboxylic acid;3-Pyridinecarboxylic acid, 2-[(4-pyridinylmethyl)amino]-;2-((pyridin-4-ylmethyl)amino)nicotinic acid hydrochloride
CBNumber:
CB32489756
Molecular Formula:
C12H11N3O2
Molecular Weight:
229.23
MDL Number:
MFCD11118784
MOL File:
854382-06-2.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:53
Product description Number Pack Size Price
2-((Pyridin-4-ylmethyl)amino)nicotinicAcid P854260 10mg $45
2-[(4-Pyridinylmethyl)amino]nicotinic acid 053464 500mg $237
2-[(4-Pyridinylmethyl)amino]nicotinic acid 053464 2.500g $720
2-[(4-PYRIDINYLMETHYL)AMINO]NICOTINIC ACID 95.00% CHM0089294 500MG $837.38
2-((Pyridin-4-ylmethyl)amino)nicotinicacid Z5193 5g $1324
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2-(pyridin-4-ylmethylamino)nicotinic acid Properties

Boiling point 461.7±40.0 °C(Predicted)
Density 1.359
storage temp. 2-8°C
pka 1.71±0.36(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT

2-(pyridin-4-ylmethylamino)nicotinic acid price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P854260 2-((Pyridin-4-ylmethyl)amino)nicotinicAcid 854382-06-2 10mg $45 2021-12-16 Buy
Matrix Scientific 053464 2-[(4-Pyridinylmethyl)amino]nicotinic acid 854382-06-2 500mg $237 2021-12-16 Buy
Matrix Scientific 053464 2-[(4-Pyridinylmethyl)amino]nicotinic acid 854382-06-2 2.500g $720 2021-12-16 Buy
American Custom Chemicals Corporation CHM0089294 2-[(4-PYRIDINYLMETHYL)AMINO]NICOTINIC ACID 95.00% 854382-06-2 500MG $837.38 2021-12-16 Buy
AK Scientific Z5193 2-((Pyridin-4-ylmethyl)amino)nicotinicacid 854382-06-2 5g $1324 2021-12-16 Buy
Product number Packaging Price Buy
P854260 10mg $45 Buy
053464 500mg $237 Buy
053464 2.500g $720 Buy
CHM0089294 500MG $837.38 Buy
Z5193 5g $1324 Buy

2-(pyridin-4-ylmethylamino)nicotinic acid Chemical Properties,Uses,Production

Synthesis

4-Pyridinemethaneamine

3731-53-1

2-Chloronicotinic acid

2942-59-8

2-(pyridin-4-ylmethylamino)nicotinic acid

854382-06-2

General procedure for the synthesis of 2-[(4-pyridinylmethyl)amino]nicotinic acid from 4-methylaminopyridine and 2-chloronicotinic acid: 2-chloronicotinic acid (25.3 mmol), a catalytic amount of copper oxide, and potassium carbonate (25.3 mmol) were added to a 100 mL round-bottomed flask, which was stirred at room temperature for 20 minutes. Subsequently, 4-dimethylaminopyridine (50.6 mmol) was added and the reaction mixture was heated to 110°C and maintained for 2 hours. After completion of the reaction, ethyl acetate was added, stirred to room temperature and then filtered. The filter cake was first washed twice with ethyl acetate and then dissolved in 20 mL of water. The pH of the solution was adjusted to 5-6 with 4N hydrochloric acid, left to stand and then filtered. The resulting filter cake was dried to obtain the crude product. The product was further purified by hot pulping with ethanol, and 5.16 g of off-white solid was obtained after filtration in 89% yield.

References

[1] Journal of Medicinal Chemistry, 2017, vol. 60, # 7, p. 2930 - 2943
[2] Patent: CN106565599, 2017, A. Location in patent: Paragraph 0082-0086
[3] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 21, p. 6003 - 6008

2-(pyridin-4-ylmethylamino)nicotinic acid Preparation Products And Raw materials

Raw materials

4-Pyridinemethaneamine 2-Chloronicotinic acid

Preparation Products

2-(pyridin-4-ylmethylamino)nicotinic acid Suppliers

Global( 33)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Baoji Guokang Healthchem Co., Ltd. 		+86-0917-3909592 +86-13892490616 gksales1@gk-bio.com China 9081 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
Shanghai Paulshine Chemical Co., Ltd. +86-021-37788663 China 186 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8667 57
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189 mychess007@163.com China 1994 55
Zhengzhou Guancheng Laboratory equipment Sales 0371-88888888 272369594 2723695949@qq.com China 4998 50
Shanghai Brain Biotechnology Co., Ltd. 13564638271 shhjiang1977@163.com China 2989 55
Supplier Advantage
Alchem Pharmtech,Inc. 		58
Baoji Guokang Healthchem Co., Ltd. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76
Shanghai Paulshine Chemical Co., Ltd. 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
ShangHai KenEn Chemical Technology Co., Ltd. 55
Zhengzhou Guancheng Laboratory equipment Sales 50
Shanghai Brain Biotechnology Co., Ltd. 55

View Lastest Price from 2-(pyridin-4-ylmethylamino)nicotinic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(pyridin-4-ylmethylamino)nicotinic acid pictures 2021-07-13 2-(pyridin-4-ylmethylamino)nicotinic acid
854382-06-2
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2-((pyridin-4-ylmethyl)amino)nicotinic acid hydrochloride 2-(pyridin-4-ylmethylamino)nicotinic acid 2-[(4-Pyridinylmethyl)amino]-3-pyridinecarboxylic acid 2-(4-pyridylmethylamino)pyridine-3-carboxylic acid 3-Pyridinecarboxylic acid, 2-[(4-pyridinylmethyl)amino]- Nicotinamide Impurity 274 854382-06-2