3-Fluoro-5-Methylanisole
- CAS No.
- 160911-11-5
- Chemical Name:
- 3-Fluoro-5-Methylanisole
- Synonyms
- 1-Fluoro-3-Methoxy-5-Methylbenzene;5-Fluoro-3-methylanisole;3-Fluoro-5-Methylanisole;3-Fluoro-5-methoxytoluene;Benzene, 1-fluoro-3-methoxy-5-methyl-
- CBNumber:
- CB32549809
- Molecular Formula:
- C8H9FO
- Molecular Weight:
- 140.15
- MDL Number:
- MFCD13185608
- MOL File:
- 160911-11-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Fluoro-5-methylanisole 99% | PC7519 | 1g | $39 |
| 3-Fluoro-5-methylanisole 99% | PC7519 | 5g | $98 |
| 1-Fluoro-3-methoxy-5-methylbenzene 98% | AS48085 | 1g | $61 |
| 1-Fluoro-3-methoxy-5-methylbenzene 98% | AS48085 | 5g | $156 |
| 1-Fluoro-3-methoxy-5-methylbenzene 98% | F49465 | 1g | $100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P280-P271 |
| HS Code | 2909309090 |
3-Fluoro-5-Methylanisole price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC7519 | 3-Fluoro-5-methylanisole 99% | 160911-11-5 | 1g | $39 | 2026-06-04 | Buy |
| Apolloscientific | PC7519 | 3-Fluoro-5-methylanisole 99% | 160911-11-5 | 5g | $98 | 2026-06-04 | Buy |
| Activate Scientific | AS48085 | 1-Fluoro-3-methoxy-5-methylbenzene 98% | 160911-11-5 | 1g | $61 | 2026-06-04 | Buy |
| Activate Scientific | AS48085 | 1-Fluoro-3-methoxy-5-methylbenzene 98% | 160911-11-5 | 5g | $156 | 2026-06-04 | Buy |
| Synthonix | F49465 | 1-Fluoro-3-methoxy-5-methylbenzene 98% | 160911-11-5 | 1g | $100 | 2026-05-06 | Buy |
3-Fluoro-5-Methylanisole Chemical Properties,Uses,Production
Uses
3-Fluoro-5-Methylanisole is utilized in various applications, including the production of pharmaceuticals, fragrances, and other fine chemicals.
Synthesis
823-96-1
29578-39-0
160911-11-5
General procedure for the synthesis of 1-fluoro-3-methoxy-5-methylbenzene from trimethylcyclotriboroxane and 3-bromo-5-fluoroanisole (Example 40): (40a) Synthesis of 1-fluoro-3-methoxy-5-methylbenzene 3-Bromo-5-fluoroanisole (2.05 g, 10 mmol), trimethylcyclotriboroxane (50% THF solution, 2.51 g, 20 mmol), PdCl2(dppf) (0.82 g, 1.0 mmol), and cesium carbonate (6.52 g, 20 mmol) were dissolved in a solvent mixture of dioxane (100 mL) and water (50 mL). It was heated and stirred under reflux conditions for 10 hours. Upon completion of the reaction, it was cooled to room temperature and water (100 mL) was added to the reaction solution, which was then extracted twice with ethyl acetate (200 mL). The organic layers were combined, washed twice with water (100 mL) and dried over anhydrous sodium sulfate. After concentration under reduced pressure, the residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate, 6:1) to afford 1-fluoro-3-methoxy-5-methylbenzene (1.40 g, yield: 66%) as a yellow oil. 1H-NMR (CDCl3, 400 MHz) δ: 1.78 (3H, s), 6.44 (1H, dd, J = 2.0, 11.0 Hz), 6.50 (1H, d, J = 11.0 Hz), 6.51 (1H, s).
References
[1] Patent: EP2138484, 2009, A1. Location in patent: Page/Page column 44
3-Fluoro-5-Methylanisole Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
3-Fluoro-5-Methylanisole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CR Corporation Limited | fred.wen@crcorporation.cn | China | 8642 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25333 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +86-13336024896 | CB@aromsyn.com | China | 19176 | 58 |
| Golden Pharma Co., Limited | +86-18958062155 | sales@zjgoldpharm.com | China | 5893 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19621 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57473 | 58 | |
| Allfluoro pharmaceutical co. ltd. | +86-400-0216110 +86-15958047586 | sales@allfluoro.com | China | 11380 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
