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Kazinol U

Kazinol U Structure
Kazinol U structure
CAS No.
1238116-48-7
Chemical Name:
Kazinol U
Synonyms
Kazinol U;4-[(2R)-3,4-Dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)-1,2-benzenediol;1,2-Benzenediol, 4-[(2S)-3,4-dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)-
CBNumber:
CB32566677
Molecular Formula:
C20H22O4
Molecular Weight:
326.39
MDL Number:
MOL File:
1238116-48-7.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:07
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Kazinol U Properties

Boiling point 538.8±50.0 °C(Predicted)
Density 1.243±0.06 g/cm3(Predicted)
storage temp. -10 to -25°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 9.72±0.40(Predicted)
form Powder
color white to beige
UNSPSC Code 12352200
NACRES NA.21

Kazinol U price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 9619AF KazinolU 1238116-48-7 10mg $2277 2021-12-16 Buy
Arctom CFN97839 KazinolU ≥98% 1238116-48-7 5mg $643 2021-12-16 Buy
Crysdot CD32002668 KazinolU 95+% 1238116-48-7 5mg $998 2021-12-16 Buy
Product number Packaging Price Buy
9619AF 10mg $2277 Buy
CFN97839 5mg $643 Buy
CD32002668 5mg $998 Buy

Kazinol U Chemical Properties,Uses,Production

Uses

Kazinol U inhibits melanogenesis through the inhibition of tyrosinase-related proteins?via?AMPK activation[1].

Biological Activity

Kazinol U is prenylated flavan isolated from an extract of Broussonetia kazinoki Sieb (paper mulberry) th at exhibits anti-melanogenic activity in mouse and human melanoma cells through the induction of AMPK and MAPK phosphorylation. Kazinol U inhibits tyrosinase activity and melanin synthesis through the reduction of MITF expression. It suppresses melanogenesis in a zebrafish model. Kazinol U displays phytoestrogenic and anti-inflammatory activities. Kazinol U exhibits cytoprotective activities against cytokine-induced apoptotic cell death.

target

Estrogen receptor | NF-kB | IkB | NO | NOS | IFN-γ | IL Receptor | IKK | Progestogen receptor

References

[1] Lim J, et al. Kazinol U inhibits melanogenesis through the inhibition of tyrosinase-related proteins via AMP kinase activation.?Br J Pharmacol. 2019;176(5):737-750. DOI:10.1111/bph.14560

Kazinol U Preparation Products And Raw materials

Raw materials

Preparation Products

Kazinol U Suppliers

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38663 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43340 58
Chembest Research Laboratories Limited +86-21-20908456 sales@BioChemBest.com China 6005 61
BioBioPha Co., Ltd. 0871-65217109 13211707573; y.liu@mail.biobiopha.com China 5653 65
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632 sales@reading-chemicals.com China 15178 58
Shanghai Yongye Biotechnology Co., Ltd. 86-021-61559134 15921386130 3423497944@qq.com China 8144 55
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6905 55
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
BOC Sciences 		58
Labnetwork lnc. 		58
TargetMol Chemicals Inc. 		58
LEAPCHEM CO., LTD. 		58
Chembest Research Laboratories Limited 61
BioBioPha Co., Ltd. 65
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Shanghai Yongye Biotechnology Co., Ltd. 55
Wuhan ChemFaces Biochemical Co., Ltd. 55

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Kazinol U 4-[(2R)-3,4-Dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)-1,2-benzenediol 1,2-Benzenediol, 4-[(2S)-3,4-dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)- 1238116-48-7