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Prostaglandin F Synthase (human recombinant)

Prostaglandin F Synthase (human recombinant) Structure
Prostaglandin F Synthase (human recombinant) structure
CAS No.
Chemical Name:
Prostaglandin F Synthase (human recombinant)
Synonyms
Prostaglandin F Synthase (human recombinant)
CBNumber:
CB32592234
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2025-08-20 16:56:13
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Prostaglandin F Synthase (human recombinant) price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10007940 Prostaglandin F Synthase (human, recombinant) ≥85%estimatedbySDS-PAGE 100μg $510 2026-04-30 Buy
Product number Packaging Price Buy
10007940 100μg $510 Buy

Prostaglandin F Synthase (human recombinant) Chemical Properties, Uses, Production

Description

Human prostaglandin F synthase (PGFS) is a ~37 kDa monomeric protein with high sequence similarity to aldo-keto reductase family members. It exhibits two related primary activities, catalyzing the isomerization of PGH2 to PGF2α (PGH2 9,11-endoperoxide reductase activity), as well as the formation of 11β-PGF2α from PGD2 (PGD2 11-ketoreductase activity) in the presence of NADPH. The enzyme also exhibits reductase activities toward carbonyl compounds such at nitroacetophenone, nitrobenzaldehyde, and 9,10-phenanthrene quinine (PQ). Cayman’s human recombinant PGFS has been expressed and purified from an E.coli overexpression system. Enzyme activity was determined by monitoring the change in absorbance at 340 nm using PGD2 as the substrate and NADPH as the cofactor (PGD2 11-ketoreductase activity).

References

[1] YOSHIHIRO URADE  Osamu H  Kikuko Watanabe. Prostaglandin D, E, and F synthases[J]. Journal of lipid mediators and cell signalling, 1995, 12 2: Pages 257-273. DOI: 10.1016/0929-7855(95)00032-l
[2] T SUZUKI. cDNA cloning, expression, and mutagenesis study of liver-type prostaglandin F synthase.[J]. The Journal of Biological Chemistry, 1999, 274 1: 241-248. DOI: 10.1074/jbc.274.1.241

Prostaglandin F Synthase (human recombinant) Preparation Products And Raw materials

Raw materials

Preparation Products

Prostaglandin F Synthase (human recombinant) Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Supplier Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58

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Prostaglandin F Synthase (human recombinant)