ChemicalBook >> CAS DataBase List >>5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester

5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester

CAS No.: 831217-40-4

Chemical Name:: 5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester

Synonyms: MAL3-101;benzyl 4-([1,1'-biphenyl]-4-yl)-1-(6-((2-(butylamino) -1-(4-(2-methoxy-2-oxoethoxy)-3-(methoxycarbonyl)phenyl)-2-oxoethyl)(hexyl)amino)-6-oxohexyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate;5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester

CBNumber:: CB32641226

Molecular Formula:: C54H66N4O10

Molecular Weight:: 931.12264

MDL Number:: MFCD20257231

MOL File:: 831217-40-4.mol

MSDS File:: SDS

Last updated:2025-04-18 09:52:09

Request For Quotation

5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester Properties

Boiling point	1037.1±65.0 °C(Predicted)
Density	1.165±0.06 g/cm3(Predicted)
pka	11.16±0.70(Predicted)
form	Solid
color	Off-white to light brown

5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0087755	MAL3-101 98.22%	831217-40-4	1mg	$357	2026-06-04	Buy
ChemScene	CS-0087755	MAL3-101 98.22%	831217-40-4	5mg	$688	2026-06-04	Buy
ChemScene	CS-0087755	MAL3-101 98.22%	831217-40-4	10mg	$1100	2026-06-04	Buy
ChemScene	CS-0087755	MAL3-101 98.22%	831217-40-4	25mg	$2199	2026-06-04	Buy
ChemScene	CS-0087755	MAL3-101 98.22%	831217-40-4	50mg	$3077	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0087755	1mg	$357	Buy
CS-0087755	5mg	$688	Buy
CS-0087755	10mg	$1100	Buy
CS-0087755	25mg	$2199	Buy
CS-0087755	50mg	$3077	Buy

5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester Chemical Properties, Uses, Production

Description

MAL3-101 is a heat shock protein 70 molecular chaperone inhibitor.

Uses

MAL3-101 is a potent HSP70 allosteric inhibitor. MAL3-101 inhibits HSP70 ATPase activity by blocking Hsp40 co-chaperone interaction. MAL3-101 can be used for researching muscle invasive bladder cancer (MIBC)[1].

IC 50

HSP70

References

[1] Prince T, et al. Dual targeting of HSP70 does not induce the heat shock response and synergistically reduces cell viability in muscle invasive bladder cancer. Oncotarget. 2018 Aug 24;9(66):32702-32717. DOI:10.18632/oncotarget.26021

5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester synthesis

Synthesis of 5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester from 4-Biphenylcarboxaldehyde

5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester Preparation Products And Raw materials

Raw materials

6-[(Aminocarbonyl)amino]hexanoic acid 4-Biphenylcarboxaldehyde 1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- N-Butylisocyanide Benzyl Acetoacetate

Hexylamine

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Preparation Products

5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester Suppliers

Global Suppliers ( 5)

Supplier	Tel	Email	Country	ProdList	Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185 18149758185	sales-cpd@caerulumpharma.com	China	3493	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29873	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32997	60

Supplier	Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
ATK CHEMICAL COMPANY LIMITED	60

831217-40-4 (5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester) Related Search:

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Luminespib

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5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester benzyl 4-([1,1'-biphenyl]-4-yl)-1-(6-((2-(butylamino) -1-(4-(2-methoxy-2-oxoethoxy)-3-(methoxycarbonyl)phenyl)-2-oxoethyl)(hexyl)amino)-6-oxohexyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate MAL3-101 831217-40-4 C54H66N4O10