ChemicalBook >> CAS DataBase List >>1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione structure

CAS No.: 114262-49-6

Chemical Name:: 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione

Synonyms: Sofosbuvir metabolites GS331007;Sofosbuvir Methylarabinosyl Impurity;Hydroxyuridine/Sofosbuvir Impurity 12;1-β-D-Arabinofuranosyluracil-2-C-methyl;1-beta-D-Arabinofuranosyluracil-2-C-methyl;1-(2'-C-methyl-β-D-arabinofuranosyl)uracil;1-(2'-C-methyl-β-D-arabinofuranosyl)uracil;1-(2-C-Methyl-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-Pyrimidinedione, 1-(2-C-methyl-β-D-arabinofuranosyl)-;1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione

CBNumber:: CB32715875

Molecular Formula:: C10H14N2O6

Molecular Weight:: 258.23

MDL Number:

MOL File:: 114262-49-6.mol

MSDS File:: SDS

Request For Quotation

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Properties

Melting point	132-135 °C
Density	1.572±0.06 g/cm3(Predicted)
pka	9.39±0.10(Predicted)

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	410359	1-β-D-Arabinofuranosyluracil-2-C-methyl	114262-49-6	25mg	$531	2026-06-03	Buy
aablocks	AA008T7G	1-β-D-Arabinofuranosyluracil-2-C-methyl >98%	114262-49-6	1mg	$1044	2026-05-28	Buy
aablocks	AA008T7G	1-β-D-Arabinofuranosyluracil-2-C-methyl 98%	114262-49-6	5mg	$1200	2026-05-28	Buy
ACHEMBLOCK	W169472	1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 98%	114262-49-6	5MG	$2095	2026-05-27	Buy
ACHEMBLOCK	W169472	1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 98%	114262-49-6	10MG	$3500	2026-05-27	Buy

Product number	Packaging	Price	Buy
410359	25mg	$531	Buy
AA008T7G	1mg	$1044	Buy
AA008T7G	5mg	$1200	Buy
W169472	5MG	$2095	Buy
W169472	10MG	$3500	Buy

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Chemical Properties, Uses, Production

Uses

1-β-D-Arabinofuranosyluracil-2-C-methyl is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Preparation Products And Raw materials

Raw materials

Preparation Products

PSI7409

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Suppliers

Global Suppliers ( 29)

Supplier	Tel	Email	Country	ProdList	Advantage
Artis Chemistry (Shanghai) Co. Ltd.	86-21-60936353		China	335	58
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7545	61
Nanjing XiZe Biotechnology CO., Ltd.	025-66023220 15250997978	1511893459@qq.com	China	4777	55
SPIRO PHARMA		eric_feng1954@126.com	China	9239	55
BOC Sciences	16314854226	info@bocsci.com	United States	9909	65
Shanghai Renshi Pharmatech Co., LTD	021-61150625 18521367657	info@renshipharma.com	China	184	55
PI & PI BIOTECH INC.	+86-13602409664 +86-17788709170	Sales@pipitech.com	China	2644	58
Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.	029-88380327 17691182729	1053@dideu.com	China	2001	58
ANHUI WITOP BIOTECH CO., LTD	+8618071025641	eric@witopchemical.com	China	23504	58
Xi'an MC Biotech, Co., Ltd.	029-89275612 +8618991951683	mcbio_sales@163.com	China	2240	58

Supplier	Advantage
Artis Chemistry (Shanghai) Co. Ltd.	58
Haoyuan Chemexpress Co., Ltd.	61
Nanjing XiZe Biotechnology CO., Ltd.	55
SPIRO PHARMA	55
BOC Sciences	65
Shanghai Renshi Pharmatech Co., LTD	55
PI & PI BIOTECH INC.	58
Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Xi'an MC Biotech, Co., Ltd.	58

114262-49-6 (1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione) Related Search:

Sofosbuvir SofosBuvir Impurity 14 SofosBuvir Impurity 52 PSI-7976 2'-deoxy-2'-fluoro-2'-C-methyluridine

SofosBuvir Impurity 50 (S)-methyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Sofosbuvir Impurity23 Sofosbuvir impurity I Sofosbuvir IMpurity C 1337482-15-1

SofosBuvir Impurity 39 1-((2S,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione sofosBuvir impurity 1 Sofosbuvir Impurity25 Sofosbuvir Impurity 5

Sofosbuvir metabolites D-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-Methyl-P-phenyl-5'-uridylyl]-, 1-Methylethyl ester SofosBuvir impurity 44

1of4

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione 1-(2-C-Methyl-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione Sofosbuvir metabolites GS331007 1-(2'-C-methyl-β-D-arabinofuranosyl)uracil Hydroxyuridine/Sofosbuvir Impurity 12 Sofosbuvir Methylarabinosyl Impurity 2,4(1H,3H)-Pyrimidinedione, 1-(2-C-methyl-β-D-arabinofuranosyl)- 1-β-D-Arabinofuranosyluracil-2-C-methyl 1-(2'-C-methyl-β-D-arabinofuranosyl)uracil 1-beta-D-Arabinofuranosyluracil-2-C-methyl 114262-49-6