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VRT-1353385

VRT-1353385 Structure
VRT-1353385 structure
CAS No.
1616113-45-1
Chemical Name:
VRT-1353385
Synonyms
Sibofimloc;EB8018;CS-1707;VRT-1353385;Antibiotic-202;VRT 1353385;VRT1353385;Sibofimloc, 10 mM in DMSO;Antibiotic 202, Sibofimloc;Antibiotic-202, VRT-1353385;Sibofimloc (VRT-1353385, Antibiotic-202)
CBNumber:
CB32741568
Molecular Formula:
C35H39NO11
Molecular Weight:
649.68
MDL Number:
MOL File:
1616113-45-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:11:47
Product description Number Pack Size Price
Sibofimloc RPC11345 50mg $828.5
Sibofimloc RPC11345 100mg $1325
Sibofimloc 99.70% CS-5487 5mg $108
Sibofimloc 99.70% CS-5487 10mg $171
Sibofimloc 99.70% CS-5487 25mg $311
Request For Quotation

VRT-1353385 Properties

storage temp. Store at -20°C
solubility ≥ 20.2mg/mL in DMSO
form Solid
color White to off-white
FDA UNII 00OF00QZC4

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

VRT-1353385 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth RPC11345 Sibofimloc 1616113-45-1 50mg $828.5 2026-06-05 Buy
Biosynth RPC11345 Sibofimloc 1616113-45-1 100mg $1325 2026-06-05 Buy
ChemScene CS-5487 Sibofimloc 99.70% 1616113-45-1 5mg $108 2026-06-04 Buy
ChemScene CS-5487 Sibofimloc 99.70% 1616113-45-1 10mg $171 2026-06-04 Buy
ChemScene CS-5487 Sibofimloc 99.70% 1616113-45-1 25mg $311 2026-06-04 Buy
Product number Packaging Price Buy
RPC11345 50mg $828.5 Buy
RPC11345 100mg $1325 Buy
CS-5487 5mg $108 Buy
CS-5487 10mg $171 Buy
CS-5487 25mg $311 Buy

VRT-1353385 Chemical Properties,Uses,Production

Uses

Sibofimloc (Antibiotic-202) is a first-in-class, gut-restricted, orally active FimH adhesion inhibitor extracted from patent WO2014100158A1, Compound Example 202. Sibofimloc has anti-bacterial infective activity. Sibofimloc is developed for inflammatory bowel disease (IBD)[1][2].

References

[1] Ramtohul, Yeeman K, et al. Preparation of mannose derivatives via coupling and click cycloaddition reactions for treating bacterial infections. From PCT Int. Appl. (2014), WO 2014100158 A1 20140626.
[2] W Reinisch, et al. P568 An open-label, multicenter, phase ib, pharmacokinetic (pk) and safety study of a fimh blocker, Sibofimloc (TAK-018/EB8018), in patients with Crohn’s disease (CD), Journal of Crohn's and Colitis, Volume 14, Issue Supplement_1, January 2020: S479–S480.

VRT-1353385 Preparation Products And Raw materials

Raw materials

Preparation Products

VRT-1353385 Suppliers

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Career Henan Chemica Co 		+86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6290 58
BOC Sciences 		16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 sales@sarms4muscle.com China 10378 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 38999 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +86-15965530500 nickzhang@hangyubiotech.com China 9935 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
Supplier Advantage
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
BOC Sciences 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Amadis Chemical Company Limited 		58
Shanghai Boyle Chemical Co., Ltd. 55

View Lastest Price from VRT-1353385 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sibofimloc pictures 2026-04-20 Sibofimloc
1616113-45-1
 $33.00-129.00 99.11% 10g TargetMol Chemicals Inc.
  • Sibofimloc pictures
  • Sibofimloc
    1616113-45-1
  • $33.00-129.00
  • 99.11%
  • TargetMol Chemicals Inc.

VRT-1353385 Spectrum

VRT-1353385(1616113-45-1)1HNMR

1616113-45-1(VRT-1353385)Related Search:

Anti-infection Compound Library Clinical Compound Library
1-[2,7-bis[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]ethynyl]spiro[fluorene-9,4'-piperidine]-1'-yl]ethanone VRT 1353385;VRT1353385 1-(2,7-bis(((2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)ethynyl)-1'l4-spiro[fluorene-9,4'-piperidin]-1'-yl)ethan-1-one Antibiotic-202, VRT-1353385 CS-1707 VRT-1353385 Antibiotic-202 8,8'-(1'-Acetylspiro[9H-fluorene-9,4'-piperidine]-2,7-diyl)bis[2,6-anhydro-7,8-dideoxy-D-glycero-D-manno-oct-7-ynitol] 1-[2,7-bis[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]ethynyl]spiro[fluorene-9,4'-piperidine]-1'-yl]ethanone Antibiotic 202, Sibofimloc D-glycero-D-manno-Oct-7-ynitol, 8,8'-(1'-acetylspiro[9H-fluorene-9,4'-piperidine]-2,7-diyl)bis[2,6-anhydro-7,8-dideoxy- EB8018 disease,Sibofimloc,Crohn's,bowel,Antibiotic202,Bacterial,IBD,inhibit,colitis,inflammatory,Antibiotic,Inhibitor,ulcerative 1-(2,7-Bis(((2R,3S,4R,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)ethynyl)spiro[fluorene-9,4'-piperidin]-1'-yl)ethan-1-one Sibofimloc, 10 mM in DMSO Sibofimloc (VRT-1353385, Antibiotic-202) 1-(2,7-Bis(((2R,3S,4R,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)ethynyl)spiro[fluorene-9,4'-piperidin]-1'-yl)ethan-1-one Sibofimloc 1616113-45-1 C35H39NO11