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ChemicalBook >> CAS DataBase List >>5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy-

5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy-

5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- Structure
5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- structure
CAS No.
1256448-47-1
Chemical Name:
5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy-
Synonyms
VRx-3996;Nanatinostat;Tractinostat);Nanatinostat TFA;CHR-3996 (Nanatinostat;NANATINOSTAT (CHR-3996);5-Pyrimidinecarboxamide, 2-[(1α,5α,6α)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy-;5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy-
CBNumber:
CB33060862
Molecular Formula:
C20H19FN6O2
Molecular Weight:
394.4
MDL Number:
MFCD28986223
MOL File:
1256448-47-1.mol
Last updated:2025-09-17 10:44:43
Product description Number Pack Size Price
Nanatinostat 98.02% CS-0006885 10mg $800
Nanatinostat 98.02% CS-0006885 25mg $1550
Nanatinostat 98.02% CS-0006885 50mg $2400
Nanatinostat 98.02% CS-0006885 100mg $3600
Nanatinostat 98.02% CS-0006885 5mg $480
Request For Quotation

5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- Properties

Density 1.51±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 8.12±0.10(Predicted)
color White to off-white
FDA UNII YTL7A418KQ

5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0006885 Nanatinostat 98.02% 1256448-47-1 10mg $800 2021-12-16 Buy
ChemScene CS-0006885 Nanatinostat 98.02% 1256448-47-1 25mg $1550 2021-12-16 Buy
ChemScene CS-0006885 Nanatinostat 98.02% 1256448-47-1 50mg $2400 2021-12-16 Buy
ChemScene CS-0006885 Nanatinostat 98.02% 1256448-47-1 100mg $3600 2021-12-16 Buy
ChemScene CS-0006885 Nanatinostat 98.02% 1256448-47-1 5mg $480 2021-12-16 Buy
Product number Packaging Price Buy
CS-0006885 10mg $800 Buy
CS-0006885 25mg $1550 Buy
CS-0006885 50mg $2400 Buy
CS-0006885 100mg $3600 Buy
CS-0006885 5mg $480 Buy

5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- Chemical Properties,Uses,Production

Uses

Nanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM[1].

References

[1] Moffat D, et al. Discovery of 2-(6-{[(6-fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-N-hydroxypyrimidine-5-carboxamide (CHR-3996), a class I selective orally active histone deacetylase inhibitor. J Med Chem. 2010 Dec 23;53(24):8663-78. DOI:10.1021/jm101177s

5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- Preparation Products And Raw materials

Raw materials

Preparation Products

5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- Suppliers

Global( 24)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32434 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19961 58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 18971495150; sales@sun-shinechem.com China 1057 64
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9729 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946 1461866103@qq.com China 16111 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988968278 YN_research@163.com China 3003 58
Suzhou Chenrui Biotechnology Co. LTD 17625585511 1580084073@qq.com China 921 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Aladdin Scientific 		58
TargetMol Chemicals Inc. 		58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
Fan De(Beijing) Biotechnology Co., Ltd. 58
Beijing xinyanhui pharmaceutical research and development co., LTD 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Guangzhou Younan Technology Co., Ltd 58
Suzhou Chenrui Biotechnology Co. LTD 58

View Lastest Price from 5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Nanatinostat pictures 2025-09-17 Nanatinostat
1256448-47-1
 US $328.00-1570.00 / mg 99.03% 10g TargetMol Chemicals Inc.
  • Nanatinostat pictures
  • Nanatinostat
    1256448-47-1
  • US $328.00-1570.00 / mg
  • 99.03%
  • TargetMol Chemicals Inc.
5-Pyrimidinecarboxamide, 2-[(1a,5a,6a)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- NANATINOSTAT (CHR-3996) Nanatinostat CHR-3996 (Nanatinostat Tractinostat) VRx-3996 5-Pyrimidinecarboxamide, 2-[(1α,5α,6α)-6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- Nanatinostat TFA 1256448-47-1