t-Boc-N-amido-PEG2-acid
- CAS No.
- 1365655-91-9
- Chemical Name:
- t-Boc-N-amido-PEG2-acid
- Synonyms
- 2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oic acid;Boc-NH-PEG2-COOH;t-boc-N-amido-PEG2-propionic acid;3-[2-(2-([(tert-Butoxy)carbonyl]amino)ethoxy)ethoxy]propanoic acid;Boc-NH-PEG2-acid;BocNH-PEG2-C2-COOH;bz-N-amido-PEG3-acid;N-Boc-amino-PEG3-acid;Boc-N-amido-PEG2-acid;t-Boc-N-amido-PEG2-PA
- CBNumber:
- CB33062664
- Molecular Formula:
- C12H23NO6
- Molecular Weight:
- 277.31
- MDL Number:
- MFCD22056304
- MOL File:
- 1365655-91-9.mol
- MSDS File:
- SDS
| Boiling point | 429.9±35.0 °C(Predicted) |
|---|---|
| Density | 1.125±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | Liquid |
| pka | 4.28±0.10(Predicted) |
| color | Colorless to light yellow |
| InChI | InChI=1S/C12H23NO6/c1-12(2,3)19-11(16)13-5-7-18-9-8-17-6-4-10(14)15/h4-9H2,1-3H3,(H,13,16)(H,14,15) |
| InChIKey | OZMXZVCAXAQCHJ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CCOCCOCCNC(=O)OC(C)(C)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P271-P261-P280 |
| HS Code | 2942000090 |
t-Boc-N-amido-PEG2-acid price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5825 | Boc-NH-PEG2-acid | 1365655-91-9 | 250MG | $141 | 2026-04-30 | Buy |
| Biosynth | FT111936 | 4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo- | 1365655-91-9 | 5g | $900 | 2026-06-04 | Buy |
| Biosynth | FT111936 | 4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo- | 1365655-91-9 | 50g | $900 | 2026-06-04 | Buy |
| Biosynth | FT111936 | 4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo- | 1365655-91-9 | 2g | $900 | 2026-06-04 | Buy |
| Biosynth | FT111936 | 4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo- | 1365655-91-9 | 25g | $900 | 2026-06-04 | Buy |
t-Boc-N-amido-PEG2-acid Chemical Properties, Uses, Production
Description
t-Boc-N-amido-PEG2-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
Boc-NH-PEG2-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].
IC 50
PEGs; Alkyl/ether
References
[1] Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis TargetingChimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable TumorRegression. J Med Chem. 2019 Jan 24;62(2):448-466. DOI:10.1021/acs.jmedchem.8b00909
t-Boc-N-amido-PEG2-acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd | 50929289 18616309303 | sales@ypptech.com.cn | China | 383 | 58 |
| CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD | 17882285575 | 1276966012@qq.com | China | 399 | 58 |
| Affinity Linkers Ltd. | 15841022315 15841022315 | sales@affinitytech.cn | China | 7039 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Chengdu Pukang Biotechnology Co., Ltd | 18217049878 | cassie.gao@pu-kang.com | China | 480 | 58 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Hygeia (Chengdu) pharmaceutical technique Co., Ltd | 028-84502008 13568869383 | sales@hygeiapharm.com | China | 291 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
View Latest Price from t-Boc-N-amido-PEG2-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-13 | t-Boc-N-amido-PEG2-acid
1365655-91-9
|
1KG | 98% | 1000 KG | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-07-24 | 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oic acid
1365655-91-9
|
1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. | ||
 |
2026-07-17 | Boc-NH-PEG2-CH2CH2COOH
1365655-91-9
|
$29.00 | 99.81% | 10g | TargetMol Chemicals Inc. |
-
- t-Boc-N-amido-PEG2-acid
1365655-91-9
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oic acid
1365655-91-9
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
-
- Boc-NH-PEG2-CH2CH2COOH
1365655-91-9
- $29.00
- 99.81%
- TargetMol Chemicals Inc.
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