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2-(Methylthio)oxazolo[4,5-b]pyridine

2-(Methylthio)oxazolo[4,5-b]pyridine structure

CAS No.: 169205-95-2

Chemical Name:: 2-(Methylthio)oxazolo[4,5-b]pyridine

Synonyms: AS0056;5Y-0215;5-b]pyridine;ZINC03884049;BUTTPARK 17\09-03;7-BroMo-3H-iMidazo[4;2-(Methylthio)oxazolo[4;7-broMo-2-Methyl-3H-iMidazo[4;2-(Methylthio)oxazolo[4,5-b]pyridine;2-Methylsulfanyl-oxazolo[5,4-b]pyridine

CBNumber:: CB3306752

Molecular Formula:: C7H6N2OS

Molecular Weight:: 166.2

MDL Number:: MFCD00973738

MOL File:: 169205-95-2.mol

MSDS File:: SDS

Last updated:2026-09-12 18:51:59

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2-(Methylthio)oxazolo[4,5-b]pyridine Properties

Melting point	59-62°
Boiling point	288.5±32.0 °C(Predicted)
Density	1.35±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	-0.41±0.50(Predicted)
Appearance	White to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	Xn
Risk Statements	22-36
Safety Statements	26
HazardClass	IRRITANT
HS Code	2934999090

2-(Methylthio)oxazolo[4,5-b]pyridine price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR904006	2-(Methylthio)oxazolo[4,5-b]pyridine >98%	169205-95-2	250mg	$21	2026-06-04	Buy
Apolloscientific	OR904006	2-(Methylthio)oxazolo[4,5-b]pyridine >98%	169205-95-2	1g	$22	2026-06-04	Buy
Apolloscientific	OR904006	2-(Methylthio)oxazolo[4,5-b]pyridine >98%	169205-95-2	5g	$101	2026-06-04	Buy
Apolloscientific	OR904006	2-(Methylthio)oxazolo[4,5-b]pyridine >98%	169205-95-2	25g	$478	2026-06-04	Buy
Matrix Scientific	044924	2-(Methylsulfanyl)[1,3]oxazolo[4,5-b]pyridine	169205-95-2	500.00mg	$181	2026-05-18	Buy

Product number	Packaging	Price	Buy
OR904006	250mg	$21	Buy
OR904006	1g	$22	Buy
OR904006	5g	$101	Buy
OR904006	25g	$478	Buy
044924	500.00mg	$181	Buy

2-(Methylthio)oxazolo[4,5-b]pyridine Chemical Properties,Uses,Production

Synthesis

53052-06-5

74-88-4

169205-95-2

Step 2: Preparation of 2-(methylthio)oxazolo[4,5-b]pyridine To a stirred solution of oxazolo[4,5-b]pyridine-2(3H)-thione (3.0 g, 19.73 mmol) in ethyl acetate (30 mL) at room temperature was sequentially added potassium carbonate (3.81 g, 27.62 mmol) and iodomethane (3.08 g, 21.71 mmol). The reaction mixture was stirred overnight at room temperature. After completion of the reaction, the mixture was diluted with water (100 mL) and extracted with ethyl acetate (2 x 50 mL). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 2-methylthiooxazolo[4,5-b]pyridine (3.0 g, 93.75% yield). 1H NMR (CDCl3, 300 MHz): δ 8.46-8.44 (d, 1H), 7.71-7.68 (d, 1H), 7.20-7.15 (m, 1H), 2.81 (s, 3H). LCMS: m/z 167.0 [M + H]+.

References

[1] Patent: WO2015/104688, 2015, A1. Location in patent: Page/Page column 36
[2] Patent: US2016/340366, 2016, A1. Location in patent: Paragraph 0207; 0208
[3] Journal of Organic Chemistry, 1995, vol. 60, # 17, p. 5721 - 5725
[4] Ultrasonics Sonochemistry, 2010, vol. 17, # 5, p. 783 - 788
[5] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 5, p. 2075 - 2078

2-(Methylthio)oxazolo[4,5-b]pyridine Preparation Products And Raw materials

Raw materials

Oxazolo[4,5-b]pyridin-2(3H)thione Iodomethane Potassium carbonate Ethyl acetate

Preparation Products

2-(Methylthio)oxazolo[4,5-b]pyridine Suppliers

Global( 92)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Shangchem Co., Ltd.	+86-21-68182121		China	881	52
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
skychemical Co.Ltd	021-20958197 20965099	sales@skychemical.com	China	1182	57
ZhengZhou HuaWen Chemical Co.Ltd	0370-2785118 17550508557	675141927@qq.com	China	3201	55
Bsisun HK Imoprt And Export Company Limited	+86-18068513926		China	1273	55
Xunteng International Trading Co.,Limited			China Hong Kong	876	55
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60

Supplier	Advantage
Wuhan Chemwish Technology Co., Ltd	56
Capot Chemical Co., Ltd	66
Shangchem Co., Ltd.	52
Pure Chemistry Scientific Inc.	62
Adamas Reagent, Ltd.	59
skychemical Co.Ltd	57
ZhengZhou HuaWen Chemical Co.Ltd	55
Bsisun HK Imoprt And Export Company Limited	55
Xunteng International Trading Co.,Limited	55
Bide Pharmatech Ltd.	60

View Lastest Price from 2-(Methylthio)oxazolo[4,5-b]pyridine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-13	2-(METHYLTHIO)OXAZOLO[4,5-B]PYRIDINE 169205-95-2	$9.80	1g	≥99%	100kg	Career Henan Chemical Co

2-(METHYLTHIO)OXAZOLO[4,5-B]PYRIDINE
169205-95-2
$9.80
≥99%
Career Henan Chemical Co

2-(Methylthio)oxazolo[4,5-b]pyridine Spectrum

2-(METHYLTHIO)OXAZOLO[4,5-B]PYRIDINE(169205-95-2)¹HNMR

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2-(METHYLSULFANYL)[1,3]OXAZOLO[4,5-B]PYRIDINE BUTTPARK 17\09-03 2-(Methylthio)[1,3]oxazolo[4,5-b]pyridine 2-Methylsulfanyl-oxazolo[5,4-b]pyridine 2-(Methylthio)oxazolo[4 5-b]pyridine 7-BroMo-3H-iMidazo[4 7-broMo-2-Methyl-3H-iMidazo[4 2-(Methylsulfanyl)oxazolo[4,5-b]pyridine 5Y-0215 AS0056 ZINC03884049 Oxazolo[4,5-b]pyridine, 2-(methylthio)- 2-(METHYLTHIO)OXAZOLO[4,5-B]PYRIDINE 169205-95-2 2-(Methylthio)oxazolo[4,5-b]pyridine 169205-95-2 Heterocycle-Pyridine series CHIRAL CHEMICALS