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2-Amino-1H-benzimidazole-5-carboxylic acid

CAS No.
76391-97-4
Chemical Name:
2-Amino-1H-benzimidazole-5-carboxylic acid
Synonyms
2-AMINO-BENZIMIDAZOLE-5-CARBOXYLIC ACID;2-amino-3h-benzimidazole-5-carboxylic Acid;2-amino-1H-Benzimidazole-6-carboxylic acid;2-Amino-1H-benzimidazole-5-carboxylic acid;1H-Benzimidazole-6-carboxylicacid, 2-amino-;2-AMINO-1H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID;2-amino-1H-benzo[d]imidazole-5-carboxylic acid;1H-Benzimidazole-5-carboxylicacid,2-amino-(9CI);2-Amino-1H-benzimidazole-5-carboxylic acid, CAS 76391-97-4
CBNumber:
CB3322932
Molecular Formula:
C8H7N3O2
Molecular Weight:
177.16
MDL Number:
MFCD03840776
MOL File:
76391-97-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:51:59

2-Amino-1H-benzimidazole-5-carboxylic acid Properties

Boiling point 540.4±42.0 °C(Predicted)
Density 1.611±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 3.17±0.30(Predicted)
Appearance Light brown to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H335-H315-H302
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26

2-Amino-1H-benzimidazole-5-carboxylic acid price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 300687 2-Amino-1H-benzo[d]imidazole-5-carboxylic acid 76391-97-4 250.00mg $45 2026-05-19 Buy
Matrix Scientific 300687 2-Amino-1H-benzo[d]imidazole-5-carboxylic acid 76391-97-4 1.00g $150 2026-05-19 Buy
Matrix Scientific 300687 2-Amino-1H-benzo[d]imidazole-5-carboxylic acid 76391-97-4 5.00g $670 2026-05-19 Buy
Synthonix A48412 2-Amino-1H-benzo[d]imidazole-5-carboxylic acid 97% 76391-97-4 100mg $39 2026-05-06 Buy
Synthonix A48412 2-Amino-1H-benzo[d]imidazole-5-carboxylic acid 97% 76391-97-4 250mg $45 2026-05-06 Buy
Product number Packaging Price Buy
300687 250.00mg $45 Buy
300687 1.00g $150 Buy
300687 5.00g $670 Buy
A48412 100mg $39 Buy
A48412 250mg $45 Buy

2-Amino-1H-benzimidazole-5-carboxylic acid Chemical Properties, Uses, Production

Synthesis

Cyanogen bromide

506-68-3

Methyl 3,4-diaminobenzoate

36692-49-6

2-AMINO-1H-BENZIMIDAZOLE-5-CARBOXYLIC ACID

76391-97-4

1. Cyanogen bromide solution (5.0 mL, 5 M in acetonitrile, 25 mmol) was slowly added to a suspension in water (50 mL) containing methyl 3,4-diaminobenzoate (3.0 g, 18 mmol). 2. The reaction mixture was stirred overnight at room temperature. 3. Upon completion of the reaction, ammonia (20 mL) and ethyl acetate (100 mL) were added to the mixture and mixed thoroughly to separate the organic and aqueous layers. 4. The organic layer was dried with anhydrous sodium sulfate, filtered to remove the desiccant, and the organic phase was subsequently concentrated under reduced pressure. 5. 2 N aqueous hydrochloric acid (18 mL, 36.0 mmol) was added to the concentrated crude product and the mixture was heated to reflux and the reaction continued overnight. 6. At the end of the reaction, the reaction mixture was concentrated under reduced pressure to afford 2-amino-1H-benzo[d]imidazole-5-carboxylic acid (2.90 g, 97% yield). 7. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.75 (s, 2H), 7.84 (s, 1H), 7.77 (dd, J = 1.2, 8.4 Hz, 1H), 7.38 (d, J = 8.4 Hz, 1H).

References

[1] Patent: US2012/108619, 2012, A1. Location in patent: Page/Page column 39
[2] Patent: US2012/270893, 2012, A1. Location in patent: Page/Page column 27

2-Amino-1H-benzimidazole-5-carboxylic acid Preparation Products And Raw materials

2-Amino-1H-benzimidazole-5-carboxylic acid Suppliers

Global Suppliers ( 69)
Supplier Tel Email Country ProdList Advantage
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd. 0515-89701588 13770166955 orgunion@orgunion.com China 620 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 546919421@qq.com China 3770 55
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
Yancheng KangdiSen Pharmaceutical Co., Ltd. 13812573443;18052965989 tongbenwan22@163.com China 1975 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 7964 55

View Latest Price from 2-Amino-1H-benzimidazole-5-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-AMINO-1H-BENZIMIDAZOLE-5-CARBOXYLIC ACID pictures 2020-03-27 2-AMINO-1H-BENZIMIDAZOLE-5-CARBOXYLIC ACID
76391-97-4
$3.00 1KG 98% 200KG Career Henan Chemical Co

2-Amino-1H-benzimidazole-5-carboxylic acid Spectrum

1H-Benzimidazole-5-carboxylicacid,2-amino-(9CI) 2-AMINO-1H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID 2-amino-1H-benzo[d]imidazole-5-carboxylic acid 2-amino-1H-Benzimidazole-6-carboxylic acid 1H-Benzimidazole-6-carboxylicacid, 2-amino- 2-AMINO-BENZIMIDAZOLE-5-CARBOXYLIC ACID 2-amino-3h-benzimidazole-5-carboxylic Acid 2-Amino-1H-benzimidazole-5-carboxylic acid, CAS 76391-97-4 2-Amino-1H-benzimidazole-5-carboxylic acid 76391-97-4 BENZIMIDAZOLE