TAMARIXETIN
- CAS No.
- 603-61-2
- Chemical Name:
- TAMARIXETIN
- Synonyms
- Aids098167;amarixetin;Chiosmethin;TAMARIXETIN;Aids-098167;tamaraxetin;TAMARIEXETIN;4’-methylquercetin;4'-Methylquercetin;4’-methoxyquercetin
- CBNumber:
- CB3328499
- Molecular Formula:
- C16H12O7
- Molecular Weight:
- 316.26
- MDL Number:
- MFCD00017308
- MOL File:
- 603-61-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Tamarixetin phyproof? Reference Substance | PHL85778 | 10MG | $734 |
| 4'-O-methyl Quercetin ≥98% | 22406 | 500μg | $49 |
| 4'-O-methyl Quercetin ≥98% | 22406 | 1mg | $93 |
| 4'-O-methyl Quercetin ≥98% | 22406 | 5mg | $294 |
| 4'-O-methyl Quercetin ≥98% | 22406 | 10mg | $539 |
| More product size | |||
| Melting point | 265-268°C |
|---|---|
| Boiling point | 601.8±55.0 °C(Predicted) |
| Density | 1.634±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: Slightly Soluble; Methanol: Slightly Soluble |
| pka | 6.31±0.40(Predicted) |
| form | A solid |
| color | Yellow to brown |
| InChI | 1S/C16H12O7/c1-22-11-3-2-7(4-9(11)18)16-15(21)14(20)13-10(19)5-8(17)6-12(13)23-16/h2-6,17-19,21H,1H3 |
| InChIKey | FPLMIPQZHHQWHN-UHFFFAOYSA-N |
| SMILES | [o]1c2c([c](c(c1c3cc(c(cc3)OC)O)O)=O)c(cc(c2)O)O |
| LogP | 2.420 (est) |
| FDA UNII | 73WRA8Z8M8 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-45 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
TAMARIXETIN price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL85778 | Tamarixetin phyproof? Reference Substance | 603-61-2 | 10MG | $734 | 2025-07-31 | Buy |
| Cayman Chemical | 22406 | 4'-O-methyl Quercetin ≥98% | 603-61-2 | 500μg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 22406 | 4'-O-methyl Quercetin ≥98% | 603-61-2 | 1mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 22406 | 4'-O-methyl Quercetin ≥98% | 603-61-2 | 5mg | $294 | 2024-03-01 | Buy |
| Cayman Chemical | 22406 | 4'-O-methyl Quercetin ≥98% | 603-61-2 | 10mg | $539 | 2024-03-01 | Buy |
TAMARIXETIN Chemical Properties,Uses,Production
Description
4''-O-methyl Quercetin is a flavonoid isolated from C. ordata with anticancer and antiplasmodial activity. 4''-O-methyl Quercetin is a major metabolite of quercetin (Item No. 10005169) that inhibits the viability of HL-60, U937, MOLT-3, Raji, K562, MCF-7, SK-MEL-1, and A549 human tumor cell lines with IC50 values ranging from 5.5-24.1 μM. It induces G2-M arrest and inhibits tubulin polymerization in vitro in a dose-dependent manner. 4''-O-methyl Quercetin inhibits breast cancer resistance protein (BCRP/ABCG2; IC50 = 40 nM in a vesicular transport assay) with no cellular toxicity indicating potential for use in overcoming multidrug resistance in chemotherapy. 4''-O-methyl Quercetin also reduces in vitro proliferation of chloroquine-resistant P. falciparum (IC50 = 4.8 μM) and suppresses infection in mice (65-81% suppression at 2.5-5 mg/kg dose).
Uses
A major metabolite of the flavanoid Quercetin (Q509500) with antioxidant properties. It helps to protect H9c2 cardiomyoblasts against H2O2-induced oxidative stress via the modulation of PI3K/Akt and ERK1/2 signaling pathways.
Definition
ChEBI: A monomethoxyflavone that is quercetin methylated at position O-4'. Isolated from Cyperus teneriffae.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
in vivo
Tamarixetin (0.2% feed management; 6 weeks) improves the myocardial hypertrophy model [2].
Tamarixetin (intraperitoneal injection; 1 mg/kg; single dose) has better anti-inflammatory properties, which is related to the increase of the immune cell population secreting IL-10 in mouse models of bacterial septicemia[3].
| Animal Model: | Transverse aortic constriction (TAC) mouse model[2] |
| Dosage: | 0.2% |
| Administration: | Feed management; 6 weeks |
| Result: | Alleviated pressureoverloadinduced cardiac hypertrophy in mice. Attenuated cardiac fibrosis and apoptosis in pressureoverloaded hearts. Suppressed oxidative stress. Negatively regulated NFAT nuclear translocation level. Was able to the down-regulate the activation of PI3K/AKT signaling pathway in the heart after pressure overload. |
References
[1] FABIO NICOLINI. Induction of G2/M phase arrest and apoptosis by the flavonoid tamarixetin on human leukemia cells.[J]. Molecular Carcinogenesis, 2014, 53 12: 939-950. DOI: 10.1002/mc.22055
[2] KEE W. TAN . Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2)[J]. Food Chemistry, 2013, 138 4: Pages 2267-2274. DOI: 10.1016/j.foodchem.2012.12.021
[3] I C EZENYI. Antiplasmodial activity-aided isolation and identification of quercetin-4’-methyl ether in Chromolaena odorata leaf fraction with high activity against chloroquine-resistant Plasmodium falciparum.[J]. Parasitology Research, 2014, 113 12: 4415-4422. DOI: 10.1007/s00436-014-4119-y
TAMARIXETIN Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29830 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32469 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9629 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 | sale03@alfachem.cn | China | 9252 | 58 |
View Lastest Price from TAMARIXETIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-02-27 | Tamarixetin
603-61-2
|
US $83.00-289.00 / mg | 98.52% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2023-02-24 | Tamarixetin
603-61-2
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
![]() |
2019-07-06 | TAMARIXETIN
603-61-2
|
US $1.00 / KG | 1g | 99% | 100KG | Career Henan Chemical Co |
-

- Tamarixetin
603-61-2
- US $83.00-289.00 / mg
- 98.52%
- TargetMol Chemicals Inc.
-

- Tamarixetin
603-61-2
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-

- TAMARIXETIN
603-61-2
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
603-61-2(TAMARIXETIN)Related Search:
1of4





