ETHYL 4-AMINO-2-(METHYLTHIO)-1,3-THIAZOLE-5-CARBOXYLATE
- CAS No.
- 39736-29-3
- Chemical Name:
- ETHYL 4-AMINO-2-(METHYLTHIO)-1,3-THIAZOLE-5-CARBOXYLATE
- Synonyms
- AKOS 92826;TIMTEC-BB SBB001485;SPECS AA-516/30012021;ETHYL 4-AMINO-2-METHYLTHIOTHIAZOLE-5-CARBOXYLATE;ethyl 4-amino-2-methylsulfanyl-thiazole-5-carboxylate;ETHYL 4-AMINO-2-(METHYLTHIO)-1,3-THIAZOLE-5-CARBOXYLATE;4-amino-2-(methylthio)-5-thiazolecarboxylic acid ethyl ester;5-Thiazolecarboxylic acid, 4-amino-2-(methylthio)-, ethyl ester
- CBNumber:
- CB3330229
- Molecular Formula:
- C7H10N2O2S2
- Molecular Weight:
- 218.3
- MDL Number:
- MFCD01830310
- MOL File:
- 39736-29-3.mol
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Ethyl 4-amino-2-(methylthio)-1,3-thiazole-5-carboxylate Asreported | 275898 | 250mg | $368 |
| Ethyl 4-amino-2-(methylthio)-1,3-thiazole-5-carboxylate Asreported | 275898 | 500mg | $509 |
| Ethyl 4-amino-2-(methylthio)-1,3-thiazole-5-carboxylate Asreported | 275898 | 1g | $902 |
| Ethyl 4-amino-2-(methylthio)-1,3-thiazole-5-carboxylate Asreported | 275898 | 2g | $1281 |
| Ethyl 4-amino-2-(methylthio)-1,3-thiazole-5-carboxylate Asreported | 275898 | 5g | $1845 |
| More product size | |||
| Melting point | 100-102 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 368.6±45.0 °C(Predicted) |
| Density | 1.37±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 1.09±0.10(Predicted) |
| Appearance | Light yellow to light brown Solid |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
ETHYL 4-AMINO-2-(METHYLTHIO)-1,3-THIAZOLE-5-CARBOXYLATE price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 275898 | Ethyl 4-amino-2-(methylthio)-1,3-thiazole-5-carboxylate Asreported | 39736-29-3 | 250mg | $368 | 2026-06-03 | Buy |
| Usbiological | 275898 | Ethyl 4-amino-2-(methylthio)-1,3-thiazole-5-carboxylate Asreported | 39736-29-3 | 500mg | $509 | 2026-06-03 | Buy |
| Usbiological | 275898 | Ethyl 4-amino-2-(methylthio)-1,3-thiazole-5-carboxylate Asreported | 39736-29-3 | 1g | $902 | 2026-06-03 | Buy |
| Usbiological | 275898 | Ethyl 4-amino-2-(methylthio)-1,3-thiazole-5-carboxylate Asreported | 39736-29-3 | 2g | $1281 | 2026-06-03 | Buy |
| Usbiological | 275898 | Ethyl 4-amino-2-(methylthio)-1,3-thiazole-5-carboxylate Asreported | 39736-29-3 | 5g | $1845 | 2026-06-03 | Buy |
ETHYL 4-AMINO-2-(METHYLTHIO)-1,3-THIAZOLE-5-CARBOXYLATE Chemical Properties,Uses,Production
Synthesis Reference(s)
Tetrahedron Letters, 7, p. 1885, 1966 DOI: 10.1016/0005-2760(66)90119-6
Synthesis
623-51-8
10191-60-3
39736-29-3
Synthesis of ethyl 4-amino-2-(methylthio)thiazole-5-carboxylate: ethyl 2-mercaptoacetate (50 g, 0.416 mol) was dissolved in 500 ml of dimethylformamide (DMF), followed by the addition of N-cyanoimino-S,S-dimethyl-dithiocarbonate (67 g, 0.416 mol) and diisopropylamine (112 ml, 0.624 mol). The reaction mixture was heated and stirred at 100 °C for 5 hours. After completion of the reaction, the mixture was poured into 500 ml of saturated ammonium chloride solution and extracted with 500 ml of ethyl acetate. The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The resulting solid was washed with hexane to give ethyl 2-methylthio-4-aminothiazole-5-carboxylate (90 g, 99% yield). The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 5.84 (broad single peak, 2H), 4.26 (quadruple peak, J=7.2 Hz, 2H), 2.63 (single peak, 3H), 1.32 (triple peak, J=7.2 Hz, 3H); LC-MS showed the molecular ion peak m/z 219 (MH+).
References
[1] Patent: US2013/72482, 2013, A1. Location in patent: Paragraph 0315-0317
[2] Patent: WO2015/89327, 2015, A1. Location in patent: Paragraph 0468
[3] Tetrahedron Letters, 1966, # 17, p. 1885 - 1889
[4] Patent: WO2015/193506, 2015, A1. Location in patent: Page/Page column 57-58
ETHYL 4-AMINO-2-(METHYLTHIO)-1,3-THIAZOLE-5-CARBOXYLATE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| ShangHai IKSChem Technology Co.,LTD | +86-18337276608 | zheng@ikschem.com | China | 2746 | 58 |
| Changzhou Exploring Chemical Co., Ltd | 15295164949 | xuf@tsourchem.com | China | 2211 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| ROSEWA HOLDING GROUP CO.,LIMITED | +86-023-62871537 | sales@rosewachem.com | China | 2812 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3544 | 55 |
| Shanghai Run-Biotech Co., Ltd. | 021-57171705 13817537615 | sales@run-biotech.com | China | 2290 | 58 |
View Lastest Price from ETHYL 4-AMINO-2-(METHYLTHIO)-1,3-THIAZOLE-5-CARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-10 | ETHYL 4-AMINO-2-(METHYLTHIO)-1,3-THIAZOLE-5-CARBOXYLATE
39736-29-3
|
$1.00 | 1KG | 98% HPLC | 10 tons/month | Career Henan Chemical Co |
-
- ETHYL 4-AMINO-2-(METHYLTHIO)-1,3-THIAZOLE-5-CARBOXYLATE
39736-29-3
- $1.00
- 98% HPLC
- Career Henan Chemical Co
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